Gene/Proteome Database (LMPD)

LMPD ID
LMP007357
Gene ID
850376
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Cwh43p
Gene Symbol
CWH43
Synonyms
-
Alternate Names
Cwh43p
Chromosome
III

Proteins

Cwh43p
Refseq ID NP_009943
Protein GI 10383785
UniProt ID P25618
mRNA ID NM_001178730
Length 953
RefSeq Status PROVISIONAL
MLIINGKIIPIAHTICAFSAFFAALVTGYSLHFHKIVTNAHYTYPDEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHYYLNQSKVCFLVGVLRTVSCGGWVYITSTDDHDIHDIFMITYIVLTLPWDIMITRYSSPLTSKNKGLTATIFFGTLFPMIYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKKIDIVLAFNEKPGNTSFFQIRDSSPINYGEEKSSELQKSGEKKVEKEKPVARSATGSYFRFDSFFYLLTNIFNGFLFWSNVTSLLCSIWHFPLWYMGISGYEAAILGYLGPIFLYLPFVSEAFTQYGVLLGGIIAIGAYIVQMPELRLISVAVGTSITVATFVQNLRYITNAETSFSFALTWLLGLVASVILKMGFYTNNPTWVILDERNGGYNKTALVLTVLFGMLSPYVNSINFEGKRNAQAKSASLIGKLFLAVGFGSLLFGIHQLLTDSSTTIYWAWEGYNESHGPLPWPWGALTCTVMLFASLSSVKFMGKPLVPCLLLLISTAVLSARSITQWPKYIFGGLLYAIAMLWLVPSYFSALGQVQNIWVYVLSFSVYIIFVLAHVWVVAYAFVPMGWVLREKIETVLAFSSTFIIIGALTCKNLNIQLVTMGKKFFIYVFFFAVALLSLTARFVYDIRPTGIPQPYHPDSQLITAGIWTIHFGLDNDMWASEDRMINLIKDMELDVVGLLETDTQRITMGNRDLTSKLAHDLNMYADFGPGPNKHTWGCVLLSKFPIVNSTHHLLPSPVGELAPAIHATLQTYNDTLVDVFVFHSGQEEDEEDRRLQSNYMAKLMGNTTRPAILLSYLVVDPGEGNYNTYVSETSGMHDIDPSDDDRWCEYILYRGLRRTGYARVARGTITDTELQVGKFQVLSEQALVEHSDSMYEYGHMSEPEYEDMKFPDKFLGEGERGHFYHVFDEPRYYL

Gene Information

Entrez Gene ID
850376
Gene Name
Cwh43p
Gene Symbol
CWH43
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005935 IDA:UniProtKB C cellular bud neck
GO:0005934 IDA:UniProtKB C cellular bud tip
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0005887 IDA:UniProtKB C integral component of plasma membrane
GO:0006506 IMP:SGD P GPI anchor biosynthetic process
GO:0071555 IGI:UniProtKB P cell wall organization
GO:0031505 IGI:SGD P fungal-type cell wall organization

Domain Information

InterPro Annotations

Accession Description
IPR005135 Endonuclease/exonuclease/phosphatase
IPR019402 Frag1/DRAM/Sfk1
IPR027317 PGAP2-interacting protein

UniProt Annotations

Entry Information

Gene Name
Cwh43p
Protein Entry
CWH43_YEAST
UniProt ID
P25618
Species
Yeast (S288c)

Comments

Comment Type Description
Domain The PGAP2-like region interacts with the PGAP2IP-like region. {ECO:0000269|PubMed:17761529}.
Function Involved in the maintenance of cell wall integrity. Required for the replacement of the diacylglycerol moiety by ceramides during GPI-anchor maturation. {ECO:0000269|PubMed:11427965, ECO:0000269|PubMed:17714445, ECO:0000269|PubMed:17761529}.
Similarity In the C-terminal section; belongs to the PGAP2IP family. {ECO:0000305}.
Similarity In the N-terminal section; belongs to the PGAP2 family. {ECO:0000305}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Concentrates to the bud tip of small budded cells and to the neck of dividing cells.

Identical and Related Proteins

Unique RefSeq proteins for LMP007357 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
10383785 RefSeq NP_009943 953 Cwh43p

Identical Sequences to LMP007357 proteins

Reference Database Accession Length Protein Name
GI:10383785 EMBL CAC42972.1 953 hypothetical protein [Saccharomyces cerevisiae]
GI:10383785 GenBank EIW11884.1 953 Cwh43p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:10383785 GenBank AHN96073.1 953 CWH43 [synthetic construct]
GI:10383785 GenBank AHV79276.1 953 CWH43 [synthetic construct]
GI:10383785 SwissProt P25618.2 953 RecName: Full=Protein CWH43; AltName: Full=Calcofluor white hypersensitive protein [Saccharomyces cerevisiae S288c]
GI:10383785 Third Party Genbank DAA07494.1 953 TPA: Cwh43p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007357 proteins

Reference Database Accession Length Protein Name
GI:10383785 EMBL CAY78220.2 953 Cwh43p [Saccharomyces cerevisiae EC1118]
GI:10383785 GenBank EDN62136.1 953 calcofluor white hypersensitive protein [Saccharomyces cerevisiae YJM789]
GI:10383785 GenBank EDV09718.1 953 calcofluor white hypersensitive protein precursor [Saccharomyces cerevisiae RM11-1a]
GI:10383785 GenBank EEU06027.1 953 Cwh43p [Saccharomyces cerevisiae JAY291]
GI:10383785 GenBank EWG97263.1 953 Cwh43p [Saccharomyces cerevisiae R103]
GI:10383785 GenBank EWH19268.1 953 Cwh43p [Saccharomyces cerevisiae P283]