LIPID MAPS

LMPD ID

LMP007355

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Msg5p

Gene Symbol

MSG5

Synonyms

-

Chromosome

XIV

EC Number

3.1.3.48;

Msg5p
Refseq ID	NP_014345
Protein GI	398365219
UniProt ID	P38590
mRNA ID	NM_001182892
Length	489
MQFHSDKQHLDSKTDIDFKPNSPRSLQNRNTKNLSLDIAALHPLMEFSSPSQDVPGSVKFPSPTPLNLFMKPKPIVLEKCPPKVSPRPTPPSLSMRRSEASIYTLPTSLKNRTVSPSVYTKSSTVSSISKLSSSSPLSSFSEKPHLNRVHSLSVKTKDLKLKGIRGRSQTISGLETSTPISSTREGTLDSTDVNRFSNQKNMQTTLIFPEEDSDLNIDMVHAEIYQRTVYLDGPLLVLPPNLYLYSEPKLEDILSFDLVINVAKEIPNLEFLIPPEMAHKIKYYHIEWTHTSKIVKDLSRLTRIIHTAHSQGKKILVHCQCGVSRSASLIVAYIMRYYGLSLNDAYNKLKGVAKDISPNMGLIFQLMEWGTMLSKNSPGEEGETVHMPEEDDIGNNEVSSTTKSYSSASFRSFPMVTNLSSSPNDSSVNSSEVTPRTPATLTGARTALATERGEDDEHCKSLSQPADSLEASVDNESISTAPEQMMFLP

Entrez Gene ID

Gene Name

Msg5p

Gene Symbol

MSG5

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005737	IDA:SGD	C	cytoplasm
GO:0005634	IDA:SGD	C	nucleus
GO:0004725	IEA:UniProtKB-EC	F	protein tyrosine phosphatase activity
GO:0008138	IDA:SGD	F	protein tyrosine/serine/threonine phosphatase activity
GO:0000754	IMP:SGD	P	adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
GO:0007049	IEA:UniProtKB-KW	P	cell cycle
GO:0000200	IDA:SGD	P	inactivation of MAPK activity involved in cell wall organization or biogenesis
GO:0071511	IDA:SGD	P	inactivation of MAPK activity involved in conjugation with cellular fusion
GO:0006470	IDA:SGD	P	protein dephosphorylation
GO:0071701	IMP:SGD	P	regulation of MAPK export from nucleus
GO:0060237	IMP:SGD	P	regulation of fungal-type cell wall organization

KEGG Pathway ID	Description
ko04011	MAPK signaling pathway - yeast
sce04011	MAPK signaling pathway - yeast

Accession	Description
IPR024950	Dual specificity phosphatase
IPR000340	Dual specificity phosphatase, catalytic domain
IPR020422	Dual specificity phosphatase, subgroup, catalytic domain
IPR016130	Protein-tyrosine phosphatase, active site
IPR029021	Protein-tyrosine phosphatase-like
IPR000387	Protein-tyrosine/Dual specificity phosphatase

Gene Name

Msg5p

Protein Entry

MSG5_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Catalytic Activity	Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Catalytic Activity	Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. {ECO:0000255\|PROSITE-ProRule:PRU10044}.
Function	Dual specificity phosphatase that dephosphorylates MAP kinase FUS3 on both a Tyr and a Ser or Thr. Has a role in adaptation to pheromone.
Induction	By pheromone.
Miscellaneous	Present with 538 molecules/cell in log phase SD medium
Miscellaneous	Present with 538 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily
Similarity	Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. {ECO:0000305}.