Gene/Proteome Database (LMPD)

LMPD ID
LMP007341
Gene ID
854352
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
putative dodecenoyl-CoA isomerase DCI1
Gene Symbol
DCI1
Synonyms
ECI2
Alternate Names
putative dodecenoyl-CoA isomerase DCI1
Chromosome
XV
EC Number
5.3.3.-

Proteins

putative dodecenoyl-CoA isomerase DCI1
Refseq ID NP_014823
Protein GI 398365593
UniProt ID Q08558
mRNA ID NM_001183599
Length 271
RefSeq Status PROVISIONAL
MSSRVCYHINGPFFIIKLIDPKHLNSLTFEDFVYIALLLHKANDIDSVLFTVLQSSGKYFSSGGKFSAVNKLNDGDVTSEVEKVSKLVSAISSPNIFVANAFAIHKKVLVCCLNGPAIGLSASLVALCDIVYSQNDSVFLLFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPVLFKELIGTIITKNYQLTNTETFNEKVLQDIKQNLEGLYPKSVLGMKELLHSEMKQKLIKAQAMETNGTLPFWASGEPFKRFKQLQEGNRRHKL

Gene Information

Entrez Gene ID
854352
Gene Name
putative dodecenoyl-CoA isomerase DCI1
Gene Symbol
DCI1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005782 IDA:SGD C peroxisomal matrix
GO:0004165 IDA:SGD F dodecenoyl-CoA delta-isomerase activity
GO:0006635 IMP:SGD P fatty acid beta-oxidation

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6837 fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)
PWY-7307 oleate beta-oxidation (reductase-dependent)
PWY-7307 oleate beta-oxidation (reductase-dependent, yeast)

Domain Information

InterPro Annotations

Accession Description
IPR029045 ClpP/crotonase-like domain
IPR001753 Crotonase_core_superfam

UniProt Annotations

Entry Information

Gene Name
putative dodecenoyl-CoA isomerase DCI1
Protein Entry
DCI1_YEAST
UniProt ID
Q08558
Species
Yeast (S288c)

Comments

Comment Type Description
Function Converts 3,5-dienoyl-CoAs to the corresponding 2,4- dienoyl-CoAs. Involved in fatty acid metabolism. Required for ECI1 to be peroxisomal located. {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:10455114, ECO:0000269|PubMed:11302517}.
Induction By oleate, through the binding of the OAF1-PIP2 transcriptional activator complex to its promoter ORE element. Expression is also induced during ammonia pulses in yeast colonies, at the beginning of detectable ammonia production. {ECO:0000269|PubMed:10455114, ECO:0000269|PubMed:10639339, ECO:0000269|PubMed:12429834, ECO:0000269|PubMed:9774671}.
Pathway Lipid metabolism; fatty acid beta-oxidation.
Similarity Belongs to the enoyl-CoA hydratase/isomerase family. {ECO:0000305}.
Subcellular Location Peroxisome {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:10455114, ECO:0000269|PubMed:10639339}.
Subunit Interacts with ECI1. {ECO:0000269|PubMed:10381339}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007341 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398365593 RefSeq NP_014823 271 putative dodecenoyl-CoA isomerase DCI1

Identical Sequences to LMP007341 proteins

Reference Database Accession Length Protein Name
GI:398365593 DBBJ GAA26496.1 271 K7_Dci1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:398365593 EMBL CAY86470.1 271 Dci1p [Saccharomyces cerevisiae EC1118]
GI:398365593 GenBank EIW07611.1 271 Dci1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:398365593 GenBank EWG83273.1 271 Dci1p [Saccharomyces cerevisiae R008]
GI:398365593 GenBank EWH16001.1 271 Dci1p [Saccharomyces cerevisiae P283]
GI:398365593 Third Party Genbank DAA10952.1 271 TPA: putative dodecenoyl-CoA isomerase DCI1 [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007341 proteins

Reference Database Accession Length Protein Name
GI:398365593 GenBank EDV10764.1 271 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase [Saccharomyces cerevisiae RM11-1a]
GI:398365593 GenBank EGA56729.1 271 Dci1p [Saccharomyces cerevisiae FostersB]
GI:398365593 GenBank EGA84664.1 271 Dci1p [Saccharomyces cerevisiae VL3]
GI:398365593 GenBank EHN04397.1 271 Dci1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:398365593 GenBank EWG88483.1 271 Dci1p [Saccharomyces cerevisiae P301]
GI:398365593 GenBank EWG93148.1 271 Dci1p [Saccharomyces cerevisiae R103]