Gene/Proteome Database (LMPD)

LMPD ID
LMP007297
Gene ID
851910
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
inositol pentakisphosphate 2-kinase
Gene Symbol
IPK1
Synonyms
GSL1
Alternate Names
inositol pentakisphosphate 2-kinase
Chromosome
IV
EC Number
2.7.1.158

Proteins

inositol pentakisphosphate 2-kinase
Refseq ID NP_010601
Protein GI 398366475
UniProt ID Q06667
mRNA ID NM_001180623
Length 281
RefSeq Status PROVISIONAL
MQVIGRGGANILIDYGDPTWLWRCCIRWPDLLSSNNSYTIKNISYIKDYVEPLLHGLLCPMYLIDVDIEAIRPILSDFILNLDDKVVKVIKIKNLTNNTSNLILNNHFLKSYCSQNLQTVILELKPKWLYYDTDYCRNCTHNAFKGRGTKYCYNQLLMNPAHLELIFGECNIFPVKFKDAMHEYLRNDNNIFKILYDLQKKLTKNTTPISDIKSINDVNDEHLLLMTLRDVTCFIEWNSAENALHVNIIDVDLKPKEKWTHWTKTYSQLTSSQKIYHTSNK

Gene Information

Entrez Gene ID
851910
Gene Name
inositol pentakisphosphate 2-kinase
Gene Symbol
IPK1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IDA:SGD C nucleus
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0035299 IDA:SGD F inositol pentakisphosphate 2-kinase activity
GO:0032958 IDA:SGD P inositol phosphate biosynthetic process
GO:0070481 IMP:SGD P nuclear-transcribed mRNA catabolic process, non-stop decay

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6361 1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)
PWY3O-402 inositol phosphate biosynthesis
PWY-6369 inositol pyrophosphates biosynthesis
PWY-6369 inositol pyrophosphates biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR009286 Inositol-pentakisphosphate 2-kinase

UniProt Annotations

Entry Information

Gene Name
inositol pentakisphosphate 2-kinase
Protein Entry
IPK1_YEAST
UniProt ID
Q06667
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity ATP + 1D-myo-inositol 1,3,4,5,6- pentakisphosphate = ADP + 1D-myo-inositol hexakisphosphate.
Domain The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.
Function Has kinase activity and phosphorylates inositol- 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate. {ECO:0000269|PubMed:10960485}.
Similarity Belongs to the IPK1 type 1 family. {ECO:0000305}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10390371}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007297 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398366475 RefSeq NP_010601 281 inositol pentakisphosphate 2-kinase

Identical Sequences to LMP007297 proteins

Reference Database Accession Length Protein Name
GI:398366475 GenBank EGA75539.1 281 Ipk1p [Saccharomyces cerevisiae AWRI796]
GI:398366475 GenBank EIW11522.1 281 Ipk1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:398366475 GenBank EWG87329.1 281 Ipk1p [Saccharomyces cerevisiae R008]
GI:398366475 GenBank EWG96611.1 281 Ipk1p [Saccharomyces cerevisiae R103]
GI:398366475 GenBank EWH19020.1 281 Ipk1p [Saccharomyces cerevisiae P283]
GI:398366475 gnl McCuskerlabDuke 281 Ipk1p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP007297 proteins

Reference Database Accession Length Protein Name
GI:398366475 DBBJ GAA22535.1 281 K7_Ipk1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:398366475 EMBL CAY78815.1 281 Ipk1p [Saccharomyces cerevisiae EC1118]
GI:398366475 GenBank EEU04803.1 281 Ipk1p [Saccharomyces cerevisiae JAY291]
GI:398366475 GenBank EGA59162.1 314 Ipk1p [Saccharomyces cerevisiae FostersB]
GI:398366475 GenBank EGA79466.1 281 Ipk1p [Saccharomyces cerevisiae Vin13]
GI:398366475 GenBank EHN07884.1 281 Ipk1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]