LIPID MAPS

LMPD ID

LMP007246

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Mrs6p

Gene Symbol

MRS6

Synonyms

MSI4

Chromosome

XV

Mrs6p
Refseq ID	NP_015015
Protein GI	6324946
UniProt ID	P32864
mRNA ID	NM_001183790
Length	603
MLSPERRPSMAERRPSFFSFTQNPSPLVVPHLAGIEDPLPATTPDKVDVLIAGTGMVESVLAAALAWQGSNVLHIDKNDYYGDTSATLTVDQIKRWVNEVNEGSVSCYKNAKLYVSTLIGSGKYSSRDFGIDLSPKILFAKSDLLSILIKSRVHQYLEFQSLSNFHTYENDCFEKLTNTKQEIFTDQNLPLMTKRNLMKFIKFVLNWEAQTEIWQPYAERTMSDFLGEKFKLEKPQVFELIFSIGLCYDLNVKVPEALQRIRRYLTSFDVYGPFPALCSKYGGPGELSQGFCRSAAVGGATYKLNEKLVSFNPTTKVATFQDGSKVEVSEKVIISPTQAPKDSKHVPQQQYQVHRLTCIVENPCTEWFNEGESAAMVVFPPGSLKSGNKEVVQAFILGAGSEICPEGTIVWYLSTTEQGPRAEMDIDAALEAMEMALLRESSSGLENDEEIVQLTGNGHTIVNSVKLGQSFKEYVPRERLQFLFKLYYTQYTSTPPFGVVNSSFFDVNQDLEKKYIPGASDNGVIYTTMPSAEISYDEVVTAAKVLYEKIVGSDDDFFDLDFEDEDEIQASGVANAEQFENAIDDDDDVNMEGSGEFVGEMEI

Entrez Gene ID

Gene Name

Mrs6p

Gene Symbol

MRS6

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005968	IDA:SGD	C	Rab-protein geranylgeranyltransferase complex
GO:0005737	IDA:SGD	C	cytoplasm
GO:0016020	IDA:SGD	C	membrane
GO:0005096	IEA:UniProtKB-KW	F	GTPase activator activity
GO:0017137	IMP:SGD	F	Rab GTPase binding
GO:0006888	IMP:SGD	P	ER to Golgi vesicle-mediated transport
GO:0032858	IMP:SGD	P	activation of Rab GTPase activity
GO:0018344	IMP:SGD	P	protein geranylgeranylation
GO:0006612	IMP:SGD	P	protein targeting to membrane

Gene Name

Mrs6p

Protein Entry

RAEP_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
Interaction	P32432:SFP1; NbExp=4; IntAct=EBI-14799, EBI-17035; P36018:YPT52; NbExp=3; IntAct=EBI-14799, EBI-29407;
Miscellaneous	Present with 23800 molecules/cell in log phase SD medium
Miscellaneous	Present with 23800 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Sequence Caution	Sequence=CAA49805.1; Type=Erroneous initiation; Evidence= ;
Sequence Caution	Sequence=CAA49805.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity	Belongs to the Rab GDI family
Similarity	Belongs to the Rab GDI family. {ECO:0000305}.