LIPID MAPS

LMPD ID

LMP007227

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Nsg2p

Gene Symbol

NSG2

Synonyms

-

Chromosome

XIV

Nsg2p
Refseq ID	NP_014243
Protein GI	398364569
UniProt ID	P53898
mRNA ID	NM_001182994
Length	299
MANRGEPDPKKSTESICSLTKPQLYSLYDDDVVRSEDNEIYEELKRSVSIDSTKYSRDQTIDSTFYLAHKVGGSLPRNTVSSNNLERILSASSIHENFPSRTRQTRQNILHYLQAVLILSLSGFAYHELSRNLHDNHLLHPDFASRPLLLGVKLCNWLSNGVLPNWLGYGVEGLLFGSVVPILDNIFQTEVVKSSVHHDSLTSVIRSINAMLGVTFGIRKIQWNSSLQAAGAWGLLNIILWLFFDGSISMLMSCICIGVGCCISCYKDIIDGSQFLYFMDFYFLGSLMFGKLGRYLYSH

Entrez Gene ID

Gene Name

Nsg2p

Gene Symbol

NSG2

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005783	IEA:UniProtKB-KW	C	endoplasmic reticulum
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0051082	IMP:SGD	F	unfolded protein binding
GO:0016126	IGI:SGD	P	sterol biosynthetic process

Accession	Description
IPR025929	Insulin-induced protein family

Gene Name

Nsg2p

Protein Entry

NSG2_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Stabilizes the HMG-CoA reductase HMG2 by preventing its HRD1-dependent degradation. Binds directly to the sterol-sensing domain (SSD)-containing transmembrane region of HMG2, promoting its folding to protect it from degradation
Function	Stabilizes the HMG-CoA reductase HMG2 by preventing its HRD1-dependent degradation. Binds directly to the sterol-sensing domain (SSD)-containing transmembrane region of HMG2, promoting its folding to protect it from degradation. {ECO:0000269\|PubMed:16270032}.
Miscellaneous	Present with 3390 molecules/cell in log phase SD medium
Miscellaneous	Present with 3390 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	To yeast YHR133c
Similarity	To yeast YHR133c. {ECO:0000305}.
Subcellular Location	Endoplasmic reticulum membrane ; Multi- pass membrane protein {ECO:0000269\|PubMed:14562095, ECO:0000269\|PubMed:16270032}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269\|PubMed:14562095, ECO:0000269\|PubMed:16270032}; Multi- pass membrane protein {ECO:0000269\|PubMed:14562095, ECO:0000269\|PubMed:16270032}.