Gene/Proteome Database (LMPD)

LMPD ID
LMP007205
Gene ID
851789
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
1-phosphatidylinositol-4-phosphate 5-kinase
Gene Symbol
MSS4
Synonyms
-
Alternate Names
1-phosphatidylinositol-4-phosphate 5-kinase
Chromosome
IV
EC Number
2.7.1.68

Proteins

1-phosphatidylinositol-4-phosphate 5-kinase
Refseq ID NP_010494
Protein GI 6320414
UniProt ID P38994
mRNA ID NM_001180516
Length 779
RefSeq Status PROVISIONAL
MSVLRSQPPSVVPLHLTTSTSRKTEQEPSLLHSAIIERHQDRSVPNSNSNPDSNHRIKKDRNNHTSYHSSSNSESNMESPRLSDGESSTPTSIEELNPTINNSRLVKRNYSISIDPLHDNSNNNTDDDHPNTITSPRPNSTSNKEMQKYSFPEGKESKKITTPSLNSNNCLDLDNSSLVHTDSYIQDLNDDHILLNKRVSRRSSRISAVTATSTTIKQRRNTQDSNLPNIPFHASKHSQILPMDDSDVIKLANGDTSMKPNSATKISHSMTSLPLHPLPQPSQKSKQYHMISKSTTSLPPENDHYYQHSRGTNHNHAANAAAVNNNTTTTTAATGLKRSESATAEIKKMRQSLLHKREMKRKRKTFLVDDDRVLIGNKVSEGHVNFIIAYNMLTGIRVAVSRCSGIMKPLTPADFRFTKKLAFDYHGNELTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYNHVRDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLKKDVELLAKLNTMDYSLLIGIHDINKAKEDDLQLADTASIEEQPQTQGPIRTGTGTVVRHFFREFEGGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLETFWRSLRHDTKLVSAIPPRDYANRFYEFIEDSVDPLPQKKTQSSYRDDPNQKNYKD

Gene Information

Entrez Gene ID
851789
Gene Name
1-phosphatidylinositol-4-phosphate 5-kinase
Gene Symbol
MSS4
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IDA:SGD C nucleus
GO:0005886 IDA:SGD C plasma membrane
GO:0016308 IDA:SGD F 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0031321 IGI:SGD P ascospore-type prospore assembly
GO:0046854 IDA:SGD P phosphatidylinositol phosphorylation

KEGG Pathway Links

KEGG Pathway ID Description
sce04144 Endocytosis
sce00562 Inositol phosphate metabolism

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY3O-242 phosphatidylinositol phosphate biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5618610 Synthesis of PIPs at the plasma membrane

Domain Information

InterPro Annotations

Accession Description
IPR023610 Phosphatidylinositol-4-phosphate 5-kinase
IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain
IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup

UniProt Annotations

Entry Information

Gene Name
1-phosphatidylinositol-4-phosphate 5-kinase
Protein Entry
MSS4_YEAST
UniProt ID
P38994
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity ATP + 1-phosphatidyl-1D-myo-inositol 4- phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
Function Catalyzes the phosphorylation of phosphatidylinositol 4- phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate. Acts downstream of STT4, but in a pathway that does not involve PKC1. May be involved in the organization of the actin cytoskeleton.
Similarity Contains 1 PIPK domain. {ECO:0000255|PROSITE- ProRule:PRU00781}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007205 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6320414 RefSeq NP_010494 779 1-phosphatidylinositol-4-phosphate 5-kinase

Identical Sequences to LMP007205 proteins

Reference Database Accession Length Protein Name
GI:6320414 EMBL CAA92347.1 779 Mss4p [Saccharomyces cerevisiae]
GI:6320414 GenBank EIW11415.1 779 Mss4p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6320414 SwissProt P38994.2 779 RecName: Full=Probable phosphatidylinositol 4-phosphate 5-kinase MSS4; AltName: Full=1-phosphatidylinositol 4-phosphate kinase; AltName: Full=Diphosphoinositide kinase; AltName: Full=PIP5K [Saccharomyces cerevisiae S288c]
GI:6320414 Third Party Genbank DAA12049.1 779 TPA: 1-phosphatidylinositol-4-phosphate 5-kinase [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007205 proteins

Reference Database Accession Length Protein Name
GI:6320414 DBBJ BAA02869.1 779 multicopy suppressor of stt4 mutation [Saccharomyces cerevisiae]
GI:6320414 EMBL CAY78710.1 779 Mss4p [Saccharomyces cerevisiae EC1118]
GI:6320414 GenBank EDV08106.1 779 phosphatidylinositol 4-phosphate kinase [Saccharomyces cerevisiae RM11-1a]
GI:6320414 GenBank EDZ73045.1 779 YDR208Wp-like protein [Saccharomyces cerevisiae AWRI1631]
GI:6320414 GenBank EHN07911.1 779 Mss4p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6320414 gnl McCuskerlabDuke 779 Mss4p [Saccharomyces cerevisiae YJM993]