Gene/Proteome Database (LMPD)

LMPD ID
LMP007173
Gene ID
850777
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Gaa1p
Gene Symbol
GAA1
Synonyms
END2
Alternate Names
Gaa1p
Chromosome
XII

Proteins

Gaa1p
Refseq ID NP_013189
Protein GI 6323117
UniProt ID P39012
mRNA ID NM_001181975
Length 614
RefSeq Status PROVISIONAL
MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQYGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSENPRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVISFVVSQAFLLIPSSGLLMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAFPMTFVKTIVESSSEHEVTTQSSNPIKTEPKDEIELVENHMDTTPATPQQQKQKLKNLVLLILTNPFISITLFGLFFDDEFHGFDIINKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSFESKSVVVRSKEKQS

Gene Information

Entrez Gene ID
850777
Gene Name
Gaa1p
Gene Symbol
GAA1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0042765 IDA:SGD C GPI-anchor transamidase complex
GO:0016255 IMP:SGD P attachment of GPI anchor to protein

KEGG Pathway Links

KEGG Pathway ID Description
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR007246 Gaa1-like, GPI transamidase component
IPR017063 Glycosylphosphatidylinositol:protein transamidase complex, GAA1 component

UniProt Annotations

Entry Information

Gene Name
Gaa1p
Protein Entry
GAA1_YEAST
UniProt ID
P39012
Species
Yeast (S288c)

Comments

Comment Type Description
Function Component of the GPI transamidase complex. Required for a terminal step of GPI anchor attachment onto proteins. Affects endocytosis.
Interaction P38875:GPI16; NbExp=3; IntAct=EBI-7252, EBI-24869; P49018:GPI8; NbExp=3; IntAct=EBI-7252, EBI-7822;
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Subunit Forms a complex with CDC91, GPI17, GPI16 and GPI8. {ECO:0000269|PubMed:11598210}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007173 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323117 RefSeq NP_013189 614 Gaa1p

Identical Sequences to LMP007173 proteins

Reference Database Accession Length Protein Name
GI:6323117 DBBJ GAA24973.1 614 K7_Gaa1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6323117 EMBL CAA97649.1 614 GAA1 [Saccharomyces cerevisiae]
GI:6323117 GenBank AAB67592.1 614 Gaa1p [Saccharomyces cerevisiae]
GI:6323117 GenBank EDN59633.1 614 GPI anchor attachment-related protein [Saccharomyces cerevisiae YJM789]
GI:6323117 GenBank EIW08705.1 614 Gaa1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6323117 Third Party Genbank DAA09404.1 614 TPA: Gaa1p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007173 proteins

Reference Database Accession Length Protein Name
GI:6323117 EMBL CAY81324.1 614 Gaa1p [Saccharomyces cerevisiae EC1118]
GI:6323117 GenBank EEU06863.1 614 Gaa1p [Saccharomyces cerevisiae JAY291]
GI:6323117 GenBank EGA77891.1 614 Gaa1p [Saccharomyces cerevisiae Vin13]
GI:6323117 GenBank EHN05891.1 614 Gaa1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6323117 GenBank EWG94698.1 614 Gaa1p [Saccharomyces cerevisiae R103]
GI:6323117 gnl McCuskerlabDuke 614 Gaa1p [Saccharomyces cerevisiae YJM993]