Gene/Proteome Database (LMPD)

LMPD ID
LMP007165
Gene ID
853465
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
Gene Symbol
TDH2
Synonyms
GLD2
Alternate Names
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
Chromosome
X
EC Number
1.2.1.12

Proteins

glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
Refseq ID NP_012542
Protein GI 6322468
UniProt ID P00358
mRNA ID NM_001181666
Length 332
RefSeq Status PROVISIONAL
MVRVAINGFGRIGRLVMRIALQRKNVEVVALNDPFISNDYSAYMFKYDSTHGRYAGEVSHDDKHIIVDGHKIATFQERDPANLPWASLNIDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSNSSIFDAAAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAKA

Gene Information

Entrez Gene ID
853465
Gene Name
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
Gene Symbol
TDH2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:SGD C cytoplasm
GO:0009277 IDA:SGD C fungal-type cell wall
GO:0005811 IDA:SGD C lipid particle
GO:0005739 IDA:SGD C mitochondrion
GO:0051287 IEA:InterPro F NAD binding
GO:0050661 IEA:InterPro F NADP binding
GO:0004365 IDA:SGD F glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0006915 IMP:SGD P apoptotic process
GO:0006094 IEP:SGD P gluconeogenesis
GO:0006096 IEP:SGD P glycolytic process
GO:0072593 IMP:SGD P reactive oxygen species metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
sce01230 Biosynthesis of amino acids
sce01200 Carbon metabolism
sce00010 Glycolysis / Gluconeogenesis

Domain Information

InterPro Annotations

Accession Description
IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site
IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I
IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family
IPR016040 NAD(P)-binding domain

UniProt Annotations

Entry Information

Gene Name
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
Protein Entry
G3P2_YEAST
UniProt ID
P00358
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH. {ECO:0000255|PROSITE-ProRule:PRU10009}.
Interaction P0CG63:UBI4; NbExp=2; IntAct=EBI-7212, EBI-7000452;
Miscellaneous Present with 121000 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Miscellaneous There are three genes for G3PDH in yeast.
Pathway Carbohydrate degradation; glycolysis; pyruvate from D- glyceraldehyde 3-phosphate: step 1/5.
Similarity Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. {ECO:0000305}.
Subcellular Location Cytoplasm.
Subunit Homotetramer.

Identical and Related Proteins

Unique RefSeq proteins for LMP007165 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6322468 RefSeq NP_012542 332 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2

Identical Sequences to LMP007165 proteins

Reference Database Accession Length Protein Name
GI:6322468 GenBank EIW09534.1 332 Tdh2p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6322468 GenBank AGV92114.1 332 Sequence 44 from patent US 8530226
GI:6322468 GenBank EWG85117.1 332 Tdh2p [Saccharomyces cerevisiae R008]
GI:6322468 GenBank EWG95121.1 332 Tdh2p [Saccharomyces cerevisiae R103]
GI:6322468 GenBank EWH17574.1 332 Tdh2p [Saccharomyces cerevisiae P283]
GI:6322468 gnl McCuskerlabDuke 332 Tdh2p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP007165 proteins

Reference Database Accession Length Protein Name
GI:6322468 DBBJ BAH03720.1 332 glyceraldehyde 3-phosphate dehydrogenase [Saccharomyces pastorianus]
GI:6322468 EMBL CAA24608.1 332 unnamed protein product [Saccharomyces cerevisiae]
GI:6322468 GenBank EHN01682.1 332 Tdh2p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6322468 GenBank EHN02219.1 332 Tdh2p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6322468 GenBank EJT43424.1 332 TDH2-like protein [Saccharomyces kudriavzevii IFO 1802]
GI:6322468 GenBank EJT44664.1 332 hypothetical protein SKUD_195508 [Saccharomyces kudriavzevii IFO 1802]