Gene/Proteome Database (LMPD)

LMPD ID
LMP007128
Gene ID
855595
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Tep1p
Gene Symbol
TEP1
Synonyms
-
Alternate Names
Tep1p
Chromosome
XIV
EC Number
3.1.3.67

Proteins

Tep1p
Refseq ID NP_014271
Protein GI 398364735
UniProt ID P53916
mRNA ID NM_001182966
Length 434
RefSeq Status PROVISIONAL
MREEGSELEMEKGFLKWKPVNLMKKILSLPMKKTKNDIGLRLDISYILVNLIVCSYPVNTYPKLLYRNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKDNDLIGIAAKFESKDFEIQELRSTLINDGKIPISPIDLETRTLVEEETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKYGMTNGVTIPSQLRYLRYHEFFITHEKAAQEGISNEAVKFKFKFRLAKMTFLRPSSLITSESAIVTTKIQHYNDDRNALLTRKVVYSDIMAHECGGNMTFIFGRDYLTLENDCRIEFTLGTSKSKAASSIISWTSCASCWLNIYLETLMHIIKDDSSPDYFQVERLKRDEMLGTTISWQELDGFGELSTHGLKLFQALKLEWEII

Gene Information

Entrez Gene ID
855595
Gene Name
Tep1p
Gene Symbol
TEP1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:SGD C cytoplasm
GO:0016314 IEA:UniProtKB-EC F phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0004725 IEA:InterPro F protein tyrosine phosphatase activity
GO:0008138 IEA:InterPro F protein tyrosine/serine/threonine phosphatase activity
GO:0030476 IMP:SGD P ascospore wall assembly

Domain Information

InterPro Annotations

Accession Description
IPR000340 Dual specificity phosphatase, catalytic domain
IPR016130 Protein-tyrosine phosphatase, active site
IPR029021 Protein-tyrosine phosphatase-like
IPR029023 Tensin phosphatase, lipid phosphatase domain

UniProt Annotations

Entry Information

Gene Name
Tep1p
Protein Entry
TEP1_YEAST
UniProt ID
P53916
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Phosphatidylinositol 3,4,5-trisphosphate + H(2)O = phosphatidylinositol 4,5-bisphosphate + phosphate.
Function May act as a phosphoinositide 3-phosphatase by regulating PtdIns(3,4,5)P3 levels. {ECO:0000269|PubMed:11070083}.
Similarity Contains 1 phosphatase tensin-type domain. {ECO:0000255|PROSITE-ProRule:PRU00590}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007128 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398364735 RefSeq NP_014271 434 Tep1p

Identical Sequences to LMP007128 proteins

Reference Database Accession Length Protein Name
GI:398364735 GenBank EEU08742.1 434 Tep1p [Saccharomyces cerevisiae JAY291]
GI:398364735 GenBank EGA85044.1 434 Tep1p [Saccharomyces cerevisiae VL3]
GI:398364735 GenBank EIW07965.1 434 Tep1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:398364735 GenBank EWH16468.1 434 Tep1p [Saccharomyces cerevisiae P283]
GI:398364735 gnl McCuskerlabDuke 434 Tep1p [Saccharomyces cerevisiae YJM993]
GI:398364735 Third Party Genbank DAA10421.1 434 TPA: Tep1p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007128 proteins

Reference Database Accession Length Protein Name
GI:398364735 DBBJ GAA25971.1 434 K7_Tep1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:398364735 EMBL CAY82476.1 434 Tep1p [Saccharomyces cerevisiae EC1118]
GI:398364735 GenBank EDN62688.1 434 tensin-like phosphatase [Saccharomyces cerevisiae YJM789]
GI:398364735 GenBank EDV12379.1 434 conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
GI:398364735 GenBank EGA60744.1 434 Tep1p [Saccharomyces cerevisiae FostersO]
GI:398364735 GenBank EHN05092.1 434 Tep1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]