Gene/Proteome Database (LMPD)

LMPD ID
LMP007126
Gene ID
850707
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Yeh2p
Gene Symbol
YEH2
Synonyms
-
Alternate Names
Yeh2p
Chromosome
XII
EC Number
3.1.1.13

Proteins

Yeh2p
Refseq ID NP_013120
Protein GI 6323048
UniProt ID Q07950
mRNA ID NM_001181907
Length 538
RefSeq Status PROVISIONAL
MVNKVVDEVQRLVSAIILTSFMTGLFILSLWKNYVTVHFQHKNDPRDTRSSRTKIQPNDKKKKRPARHSRPLSISSTTPLDLQRDQENNIEYDRTVTSKLSMTSNASLSENGDGNANIKMETNVNQAPYAAENPFQNIALAEDTKLVPDLKYYYKEYGIDIEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLLQSCGAFASSGRKSLAYFLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKKWDWDMHQMVQYDLKALINYVLDSTGYAKLSLVAHSQGTTQGFMGLVNGEKLYASDFKLVDKLENFVALAPAVYPGPLLDEKAFVRLMAKGIDSPWYFGRRSFIPLMMTMRKLMVGTKIFSFLSYIMFNYLFDWNDVLWDRVLRDRNFLFSPVHISVKLMQWWLSPLPNKLSFKKGAEKIFPDKKTWFPIAKNDDDSGNNLDNNKLHLNPKRQNSEEFPHIIMFIPKQDRLVDGERLINHFINHEANAVYKIWYIDEYSHLDVLWAHDVIDRIGKPMIENLRFPNAR

Gene Information

Entrez Gene ID
850707
Gene Name
Yeh2p
Gene Symbol
YEH2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IDA:SGD C integral component of membrane
GO:0005886 IDA:SGD C plasma membrane
GO:0004771 IDA:SGD F sterol esterase activity
GO:0000032 IMP:SGD P cell wall mannoprotein biosynthetic process
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0016125 IMP:SGD P sterol metabolic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-7424 sterol:steryl ester interconversion
PWY-7424 sterol:steryl ester interconversion (yeast)

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR006693 Partial AB-hydrolase lipase domain

UniProt Annotations

Entry Information

Gene Name
Yeh2p
Protein Entry
YEH2_YEAST
UniProt ID
Q07950
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity A steryl ester + H(2)O = a sterol + a fatty acid.
Function Mediates the hydrolysis of steryl esters. Required for mobilization of steryl ester, thereby playing a central role in lipid metabolism. {ECO:0000269|PubMed:15632184, ECO:0000269|PubMed:15713625}.
Miscellaneous Present with 1630 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Ptm Not glycosylated.
Similarity Belongs to the AB hydrolase superfamily. {ECO:0000305}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15632184, ECO:0000269|PubMed:15713625}; Single-pass type II membrane protein {ECO:0000269|PubMed:15632184, ECO:0000269|PubMed:15713625}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007126 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323048 RefSeq NP_013120 538 Yeh2p

Identical Sequences to LMP007126 proteins

Reference Database Accession Length Protein Name
GI:6323048 DBBJ GAA24907.1 538 K7_Yeh2p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6323048 EMBL CAA97543.1 538 unnamed protein product [Saccharomyces cerevisiae]
GI:6323048 SwissProt Q07950.1 538 RecName: Full=Sterol esterase 2; AltName: Full=Steryl ester hydrolase 2 [Saccharomyces cerevisiae S288c]
GI:6323048 Third Party Genbank DAA09338.1 538 TPA: Yeh2p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007126 proteins

Reference Database Accession Length Protein Name
GI:6323048 EMBL CAY81258.1 538 Yeh2p [Saccharomyces cerevisiae EC1118]
GI:6323048 GenBank EDV09328.1 538 hypothetical protein SCRG_05008 [Saccharomyces cerevisiae RM11-1a]
GI:6323048 GenBank EEU04500.1 538 Yeh2p [Saccharomyces cerevisiae JAY291]
GI:6323048 GenBank EGA81777.1 538 Yeh2p [Saccharomyces cerevisiae Lalvin QA23]
GI:6323048 GenBank EWG84299.1 538 Yeh2p [Saccharomyces cerevisiae R008]
GI:6323048 GenBank EWH17195.1 538 Yeh2p [Saccharomyces cerevisiae P283]