Gene/Proteome Database (LMPD)

LMPD ID
LMP007114
Gene ID
851807
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Gtb1p
Gene Symbol
GTB1
Synonyms
-
Alternate Names
Gtb1p
Chromosome
IV

Proteins

Gtb1p
Refseq ID NP_010507
Protein GI 398366171
UniProt ID Q04924
mRNA ID NM_001180529
Length 702
RefSeq Status PROVISIONAL
MVSMFSLFLLLIEQSPLVASLQQSQRHIVGVPWEKQHLYDSNEPDLTKWHCLNHEDIVLDISQINDGVCDCPDGSDEPGSAACVEDIFKSVAEGGGKVNKYFYCDNKGFIPRYIRKSEVADGICDCCDCSDELLSGYELFDAGSNCSQLKNEFDIMASKELSSYREGKEALEELERKYGTKEEAITRGNCLEEDKEKASAEIKVLSNRLSENRAKLEQLRGEYFNQLSHDPILYQFEQLNSTRLGSDILTSFTMVSRVSKGYQDIFKILSDLSEAYTPSLNDKVVNDNIKKFRKVRRRAEKAKINADSKIDDEQADNLYLYFTEEVPQIFLKRESENTLRYVIGKSNFVQALVEGKINYTNDILEYIREFRLIMDDISQNYNVNFQDAGVKSAVDSYKNYLGEYGELAELEPAHPSESLLRSLSEVTSFVNENAPKVLPPDAVESEQDTNSDHIGTSGDLRNKLKEILSKLNIFSSRKDLVSLEKRFRSCESQVSLLENELKQKMDYKKLLDETEDEGTNSTAGNLTELLELMGSQSYCLDDILDNYVYTICFQRPMTEGVIYQAEDKVDGKKVLIGRFKTSGFNVDLNMEKYAEHLKATYDEKSDLISNLAAIQDDDGNMQHYVFGNLNELNNGLVLEYENGDQCWNGPRRSATVFVRCSDKFKIRSVHEATKCNYIFDVVGPLGCNKTFEYEPPKFNLSE

Gene Information

Entrez Gene ID
851807
Gene Name
Gtb1p
Gene Symbol
GTB1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005788 IDA:SGD C endoplasmic reticulum lumen
GO:0017177 IPI:SGD C glucosidase II complex
GO:0006491 IEA:InterPro P N-glycan processing
GO:0000271 IMP:SGD P polysaccharide biosynthetic process
GO:0006487 IMP:SGD P protein N-linked glycosylation

REACTOME Pathway Links

REACTOME Pathway ID Description
5618554 Advanced glycosylation endproduct receptor signaling
5618178 Immune System
5618189 Innate Immune System

Domain Information

InterPro Annotations

Accession Description
IPR026874 Glucosidase 2 subunit beta
IPR028146 Glucosidase II beta subunit, N-terminal
IPR012913 Glucosidase II beta subunit-like
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR009011 Mannose-6-phosphate receptor binding domain

UniProt Annotations

Entry Information

Gene Name
Gtb1p
Protein Entry
GLU2B_YEAST
UniProt ID
Q04924
Species
Yeast (S288c)

Comments

Comment Type Description
Function Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Specifically required for the cleavage of the final glucose. {ECO:0000269|PubMed:16373354}.
Miscellaneous Present with 9760 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Subcellular Location Endoplasmic reticulum {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16373354}.
Subunit Heterodimer of a catalytic subunit alpha (ROT2) and a subunit beta (GTB1).

Identical and Related Proteins

Unique RefSeq proteins for LMP007114 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398366171 RefSeq NP_010507 702 Gtb1p

Identical Sequences to LMP007114 proteins

Reference Database Accession Length Protein Name
GI:398366171 GenBank EDN60555.1 702 glucosidase II beta subunit [Saccharomyces cerevisiae YJM789]
GI:398366171 GenBank EDV08095.1 702 hypothetical protein SCRG_00303 [Saccharomyces cerevisiae RM11-1a]
GI:398366171 GenBank EDZ73035.1 702 YDR221Wp-like protein [Saccharomyces cerevisiae AWRI1631]
GI:398366171 GenBank EIW11426.1 702 Gtb1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:398366171 gnl McCuskerlabDuke 702 Gtb1p [Saccharomyces cerevisiae YJM993]
GI:398366171 Third Party Genbank DAA12063.1 702 TPA: Gtb1p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007114 proteins

Reference Database Accession Length Protein Name
GI:398366171 DBBJ GAA22448.1 702 K7_Gtb1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:398366171 EMBL CAY78721.1 702 Gtb1p [Saccharomyces cerevisiae EC1118]
GI:398366171 GenBank EEU05239.1 702 Gtb1p [Saccharomyces cerevisiae JAY291]
GI:398366171 GenBank EHN07805.1 699 Gtb1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:398366171 GenBank EWG91922.1 702 Gtb1p [Saccharomyces cerevisiae P301]
GI:398366171 GenBank EWG97167.1 702 Gtb1p [Saccharomyces cerevisiae R103]