LIPID MAPS

LMPD ID

LMP007024

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Bet2p

Gene Symbol

BET2

Synonyms

-

Chromosome

XVI

EC Number

2.5.1.60

Bet2p
Refseq ID	NP_015502
Protein GI	6325434
UniProt ID	P20133
mRNA ID	NM_001184273
Length	325
MSGSLTLLKEKHIRYIESLDTKKHNFEYWLTEHLRLNGIYWGLTALCVLDSPETFVKEEVISFVLSCWDDKYGAFAPFPRHDAHLLTTLSAVQILATYDALDVLGKDRKVRLISFIRGNQLEDGSFQGDRFGEVDTRFVYTALSALSILGELTSEVVDPAVDFVLKCYNFDGGFGLCPNAESHAAQAFTCLGALAIANKLDMLSDDQLEEIGWWLCERQLPEGGLNGRPSKLPDVCYSWWVLSSLAIIGRLDWINYEKLTEFILKCQDEKKGGISDRPENEVDVFHTVFGVAGLSLMGYDNLVPIDPIYCMPKSVTSKFKKYPYK

Entrez Gene ID

Gene Name

Bet2p

Gene Symbol

BET2

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005968	IDA:SGD	C	Rab-protein geranylgeranyltransferase complex
GO:0017137	ISS:UniProtKB	F	Rab GTPase binding
GO:0004663	IDA:SGD	F	Rab geranylgeranyltransferase activity
GO:0008270	ISS:UniProtKB	F	zinc ion binding
GO:0006888	IMP:SGD	P	ER to Golgi vesicle-mediated transport
GO:0018344	IDA:SGD	P	protein geranylgeranylation
GO:0006612	IMP:SGD	P	protein targeting to membrane

Accession	Description
IPR026873	Geranylgeranyl transferase type-2 subunit beta
IPR001330	Prenyltransferase/squalene oxidase
IPR008930	Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid

Gene Name

Bet2p

Protein Entry

PGTB2_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Catalytic Activity	Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.
Cofactor	Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence= ; Note=Binds 1 zinc ion per subunit. ;
Cofactor	Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 1 zinc ion per subunit. {ECO:0000250};
Function	Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both cysteines may become modified. Acts on YPT1 and SEC4.
Interaction	Q00618:BET4; NbExp=3; IntAct=EBI-3559, EBI-3573;
Miscellaneous	Present with 1520 molecules/cell in log phase SD medium
Miscellaneous	Present with 1520 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	Belongs to the protein prenyltransferase subunit beta family
Similarity	Belongs to the protein prenyltransferase subunit beta family. {ECO:0000305}.
Similarity	Contains 6 PFTB repeats
Similarity	Contains 6 PFTB repeats. {ECO:0000305}.
Subunit	Heterodimer of an alpha and a beta subunit.