Gene/Proteome Database (LMPD)

LMPD ID
LMP007013
Gene ID
855026
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Sec59p
Gene Symbol
SEC59
Synonyms
-
Alternate Names
Sec59p
Chromosome
XIII
EC Number
2.7.1.108

Proteins

Sec59p
Refseq ID NP_013726
Protein GI 6323655
UniProt ID P20048
mRNA ID NM_001182509
Length 519
RefSeq Status PROVISIONAL
MVAIIPHASFTTIKLTQKTEGSQMPTEEICKINMRTRKFDVGGNSRDFECFYSNFVQTVILLGTFFYCVERLQPWSIVTADISYKQIFVNVFVVCLIMVGLIFTKYWQHGYKSLPKFDTIYSLYLPFMVSLLFDTSSTVINTILILSVLNSYRWRTQLVVIILQLCLIFFNFEAGDRLKNIISIVINSLLSLILKYIGQLKSLDNIDSNLFSILLTNILYVSEAGTVHFRILKGIILALTTIISINYVLKKVMHFKPFMLSISFAIGLPLFANTFIHLEDGENPLLWLVKYILESTIRQKILFAWSSILILSIPSILIEKDSLSLNTSRKLWHFIIFLLIIPSFQMDSNFVKIALSGTIPVFLSIEYIRFQNLPPLGSAIELQLRRFADDRDHSGPLIISYLYLLFGISTPLLMNNSPMGLIGLGIGDSLASIIGKRYGRIRWKGTQKTLEGTLAFIVTSFIVCLVLLRFDKAAIFNHLTTLQLLTLCTLSGVLEGNSVLNDNILIPAFMMICEKLITL

Gene Information

Entrez Gene ID
855026
Gene Name
Sec59p
Gene Symbol
SEC59
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IDA:SGD C endoplasmic reticulum membrane
GO:0030176 IEA:InterPro C integral component of endoplasmic reticulum membrane
GO:0004168 IMP:SGD F dolichol kinase activity
GO:0043048 IEA:InterPro P dolichyl monophosphate biosynthetic process
GO:0006486 IMP:SGD P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
sce01100 Metabolic pathways
ko00510 N-Glycan biosynthesis
sce00510 N-Glycan biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5618347 Synthesis of Dolichyl-phosphate

Domain Information

InterPro Annotations

Accession Description
IPR026566 Dolichol kinase
IPR000374 Phosphatidate cytidylyltransferase

UniProt Annotations

Entry Information

Gene Name
Sec59p
Protein Entry
SEC59_YEAST
UniProt ID
P20048
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity CTP + dolichol = CDP + dolichyl phosphate.
Function Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. It is required for spore germination. Has an essential role in cellular metabolism.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the polyprenol kinase family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007013 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323655 RefSeq NP_013726 519 Sec59p

Identical Sequences to LMP007013 proteins

Reference Database Accession Length Protein Name
GI:6323655 EMBL CAA88530.1 519 Sec59p [Saccharomyces cerevisiae]
GI:6323655 GenBank AAA35033.1 519 SEC59 [Saccharomyces cerevisiae]
GI:6323655 GenBank AAT92848.1 519 YMR013C [Saccharomyces cerevisiae]
GI:6323655 GenBank ABU29208.1 519 Sequence 35 from patent US 7230165
GI:6323655 GenBank EIW08272.1 519 Sec59p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6323655 Third Party Genbank DAA09911.1 519 TPA: Sec59p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007013 proteins

Reference Database Accession Length Protein Name
GI:6323655 DBBJ GAA25457.1 519 K7_Sec59p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6323655 EMBL CAY81835.1 519 Sec59p [Saccharomyces cerevisiae EC1118]
GI:6323655 GenBank EDN64404.1 519 secretory subuint [Saccharomyces cerevisiae YJM789]
GI:6323655 GenBank EDV11517.1 519 membrane protein [Saccharomyces cerevisiae RM11-1a]
GI:6323655 GenBank EGA77501.1 519 Sec59p [Saccharomyces cerevisiae Vin13]
GI:6323655 gnl McCuskerlabDuke 519 Sec59p [Saccharomyces cerevisiae YJM993]