Gene/Proteome Database (LMPD)

LMPD ID
LMP007005
Gene ID
853296
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Sfh5p
Gene Symbol
SFH5
Synonyms
-
Alternate Names
Sfh5p
Chromosome
X

Proteins

Sfh5p
Refseq ID NP_012390
Protein GI 6322316
UniProt ID P47008
mRNA ID NM_001181578
Length 294
RefSeq Status PROVISIONAL
MKFDNDSEKQVFDKLKKAIPGIIKEKCAGYDELYGYKLNPEGLTQEEVDKYYDEKIADRLTYKLCKAYQFEYSTIVQNLIDILNWRREFNPLSCAYKEVHNTELQNVGILTFDANGDANKKAVTWNLYGQLVKKKELFQNVDKFVRYRIGLMEKGLSLLDFTSSDNNYMTQVHDYKGVSVWRMDSDIKNCSKTVIGIFQKYYPELLYAKYFVNVPTVFGWVYDLIKKFVDETTRKKFVVLTDGSKLGQYLKDCPYEGYGGKDKKNNLTKQNVTNVHPTEYGLYILQKQIIEDVE

Gene Information

Entrez Gene ID
853296
Gene Name
Sfh5p
Gene Symbol
SFH5
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0071944 IDA:SGD C cell periphery
GO:0032541 IDA:SGD C cortical endoplasmic reticulum
GO:0005829 IDA:SGD C cytosol
GO:0005886 IDA:SGD C plasma membrane
GO:0008526 IDA:SGD F phosphatidylinositol transporter activity
GO:0043001 IGI:SGD P Golgi to plasma membrane protein transport
GO:0046488 IGI:SGD P phosphatidylinositol metabolic process
GO:0015914 IDA:SGD P phospholipid transport
GO:2000114 IGI:SGD P regulation of establishment of cell polarity
GO:0017157 IGI:SGD P regulation of exocytosis

Domain Information

InterPro Annotations

Accession Description
IPR001251 CRAL-TRIO domain
IPR011074 CRAL/TRIO, N-terminal domain

UniProt Annotations

Entry Information

Gene Name
Sfh5p
Protein Entry
SFH5_YEAST
UniProt ID
P47008
Species
Yeast (S288c)

Comments

Comment Type Description
Function Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. {ECO:0000269|PubMed:10848624, ECO:0000269|PubMed:12869188, ECO:0000269|PubMed:16709158}.
Miscellaneous Present with 6540 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the SFH5 family. {ECO:0000305}.
Similarity Contains 1 CRAL-TRIO domain. {ECO:0000255|PROSITE- ProRule:PRU00056}.
Subcellular Location Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP007005 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6322316 RefSeq NP_012390 294 Sfh5p

Identical Sequences to LMP007005 proteins

Reference Database Accession Length Protein Name
GI:6322316 GenBank EHN06431.1 294 Sfh5p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6322316 GenBank EIW09717.1 294 Sfh5p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6322316 GenBank EWG84992.1 294 Sfh5p [Saccharomyces cerevisiae R008]
GI:6322316 GenBank EWG95301.1 294 Sfh5p [Saccharomyces cerevisiae R103]
GI:6322316 GenBank EWH17747.1 294 Sfh5p [Saccharomyces cerevisiae P283]
GI:6322316 gnl McCuskerlabDuke 294 Sfh5p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP007005 proteins

Reference Database Accession Length Protein Name
GI:6322316 DBBJ GAA24219.1 294 K7_Sfh5p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6322316 GenBank AAS56909.1 294 YJL145W [Saccharomyces cerevisiae]
GI:6322316 GenBank EEU07116.1 294 Sfh5p [Saccharomyces cerevisiae JAY291]
GI:6322316 GenBank EHN01793.1 294 Sfh5p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6322316 GenBank EJS43230.1 294 sfh5p [Saccharomyces arboricola H-6]
GI:6322316 GenBank EJT43886.1 294 SFH5-like protein [Saccharomyces kudriavzevii IFO 1802]