LIPID MAPS

LMPD ID

LMP006877

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

long-chain fatty acid transporter FAT1

Gene Symbol

FAT1

Synonyms

-

Chromosome

II

long-chain fatty acid transporter FAT1
Refseq ID	NP_009597
Protein GI	41629676
UniProt ID	P38225
mRNA ID	NM_001178389
Length	669
MSPIQVVVFALSRIFLLLFRLIKLIITPIQKSLGYLFGNYFDELDRKYRYKEDWYIIPYFLKSVFCYIIDVRRHRFQNWYLFIKQVQQNGDHLAISYTRPMAEKGEFQLETFTYIETYNIVLRLSHILHFDYNVQAGDYVAIDCTNKPLFVFLWLSLWNIGAIPAFLNYNTKGTPLVHSLKISNITQVFIDPDASNPIRESEEEIKNALPDVKLNYLEEQDLMHELLNSQSPEFLQQDNVRTPLGLTDFKPSMLIYTSGTTGLPKSAIMSWRKSSVGCQVFGHVLHMTNESTVFTAMPLFHSTAALLGACAILSHGGCLALSHKFSASTFWKQVYLTGATHIQYVGEVCRYLLHTPISKYEKMHKVKVAYGNGLRPDIWQDFRKRFNIEVIGEFYAATEAPFATTTFQKGDFGIGACRNYGTIIQWFLSFQQTLVRMDPNDDSVIYRNSKGFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRDVFRRGDAWYRCGDLLKADEYGLWYFLDRMGDTFRWKSENVSTTEVEDQLTASNKEQYAQVLVVGIKVPKYEGRAGFAVIKLTDNSLDITAKTKLLNDSLSRLNLPSYAMPLFVKFVDEIKMTDNHKILKKVYREQKLPKGLDGNDTIFWLKNYKRYEVLTAADWEAIDAQTIKL

Entrez Gene ID

Gene Name

long-chain fatty acid transporter FAT1

Gene Symbol

FAT1

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005783	IDA:SGD	C	endoplasmic reticulum
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0031235	IDA:SGD	C	intrinsic component of the cytoplasmic side of the plasma membrane
GO:0005811	IDA:SGD	C	lipid particle
GO:0005777	IMP:SGD	C	peroxisome
GO:0005324	IMP:SGD	F	long-chain fatty acid transporter activity
GO:0031957	IMP:SGD	F	very long-chain fatty acid-CoA ligase activity
GO:0015909	IMP:SGD	P	long-chain fatty acid transport
GO:0000038	IMP:SGD	P	very long-chain fatty acid metabolic process

BIOCYC Pathway ID	Description
PWY-7288	fatty acid beta-oxidation (peroxisome)
YEAST-FAO-PWY	fatty acid oxidation (non-cyclic)

REACTOME Pathway ID	Description
5618090	Fatty acid, triacylglycerol, and ketone body metabolism
5618023	Metabolism
5618091	Metabolism of lipids and lipoproteins
5618608	PPARA activates gene expression
5618609	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
5618036	SLC-mediated transmembrane transport
5618037	Transmembrane transport of small molecules
5618556	Transport of fatty acids
5618137	Transport of vitamins, nucleosides, and related molecules

Accession	Description
IPR020845	AMP-binding, conserved site
IPR000873	AMP-dependent synthetase/ligase

Gene Name

long-chain fatty acid transporter FAT1

Protein Entry

FAT1_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	May be involved in long-chain fatty acids uptake, and thus may play a pivotal role in regulating their accessibility prior to metabolic utilization. May play an important role in uptake of these hydrophobic compounds under conditions where fatty acid synthesis is compromised.
Miscellaneous	Present with 16900 molecules/cell in log phase SD medium
Miscellaneous	Present with 16900 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Sequence Caution	Sequence=CAA84983.1; Type=Frameshift; Positions=620; Evidence= ;
Sequence Caution	Sequence=CAA84983.1; Type=Frameshift; Positions=620; Evidence={ECO:0000305};
Similarity	Belongs to the ATP-dependent AMP-binding enzyme family
Similarity	Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.
Subcellular Location	Membrane ; Multi-pass membrane protein .
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.