Gene/Proteome Database (LMPD)

LMPD ID
LMP006829
Gene ID
855457
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Pdr17p
Gene Symbol
PDR17
Synonyms
ISS1; SFH4
Alternate Names
Pdr17p
Chromosome
XIV

Proteins

Pdr17p
Refseq ID NP_014135
Protein GI 6324065
UniProt ID P53844
mRNA ID NM_001183102
Length 350
RefSeq Status PROVISIONAL
MGLFSRKRDHTPAVPKEKLIPCDKIFLDPPAKYGNAPLLEPISEDQNEKYRAVLRHFQDDDLKLPENLNDLDNGTHANDRPLSDWEKFWLSRECFLRYLRANKWNTANAIKGLTKTLVWRREIGLTHGKEDKDPLTADKVAVENETGKQVILGFDNAKRPLYYMKNGRQNTESSFRQVQELVYMMETATTVAPQGVEKITVLVDFKSYKEPGIITDKAPPISIARMCLNVMQDHYPERLAKCVLINIPWFAWAFLKMMYPFLDPATKAKAIFDEPFENHIEPSQLDALYNGLLDFKYKHEVYWPDMVKKVDDLRLKRFDRFLKFGGIVGLSEYDTKGQHDELKYPVDMVI

Gene Information

Entrez Gene ID
855457
Gene Name
Pdr17p
Gene Symbol
PDR17
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0071944 IDA:SGD C cell periphery
GO:0005829 IDA:SGD C cytosol
GO:0005768 IDA:SGD C endosome
GO:0008526 IDA:SGD F phosphatidylinositol transporter activity
GO:0043001 IGI:SGD P Golgi to plasma membrane protein transport
GO:1901352 IGI:SGD P negative regulation of phosphatidylglycerol biosynthetic process
GO:0006658 IMP:SGD P phosphatidylserine metabolic process
GO:0008654 IGI:SGD P phospholipid biosynthetic process
GO:0015914 IDA:SGD P phospholipid transport
GO:2001247 IGI:SGD P positive regulation of phosphatidylcholine biosynthetic process
GO:0042493 IGI:SGD P response to drug
GO:0016126 IGI:SGD P sterol biosynthetic process

Domain Information

InterPro Annotations

Accession Description
IPR001251 CRAL-TRIO domain
IPR011074 CRAL/TRIO, N-terminal domain

UniProt Annotations

Entry Information

Gene Name
Pdr17p
Protein Entry
PDR17_YEAST
UniProt ID
P53844
Species
Yeast (S288c)

Comments

Comment Type Description
Function Has phosphatidylinositol transfer activity. Involved in the regulation of the phospholipid composition of plasma- and endomembranes. Altering plasma membrane composition may provide a possible mechanism for multidrug resistance. Contributes to efficient phospholipase D1 activation and phospholipase B1 inhibition in the regulation of phospholipid turnover. {ECO:0000269|PubMed:10799527, ECO:0000269|PubMed:10848624, ECO:0000269|PubMed:9890948}.
Miscellaneous Present with 5040 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Contains 1 CRAL-TRIO domain. {ECO:0000255|PROSITE- ProRule:PRU00056}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12869188, ECO:0000269|PubMed:14562095}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006829 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6324065 RefSeq NP_014135 350 Pdr17p

Identical Sequences to LMP006829 proteins

Reference Database Accession Length Protein Name
GI:6324065 GenBank EIW08188.1 350 Pdr17p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6324065 GenBank EWG83606.1 350 Pdr17p [Saccharomyces cerevisiae R008]
GI:6324065 GenBank EWG89012.1 350 Pdr17p [Saccharomyces cerevisiae P301]
GI:6324065 GenBank EWG93909.1 350 Pdr17p [Saccharomyces cerevisiae R103]
GI:6324065 GenBank EWH16365.1 350 Pdr17p [Saccharomyces cerevisiae P283]
GI:6324065 gnl McCuskerlabDuke 350 Pdr17p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP006829 proteins

Reference Database Accession Length Protein Name
GI:6324065 DBBJ GAA25843.1 350 K7_Pdr17p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6324065 EMBL CAY82348.1 350 Pdr17p [Saccharomyces cerevisiae EC1118]
GI:6324065 GenBank EGA81068.1 350 Pdr17p [Saccharomyces cerevisiae Lalvin QA23]
GI:6324065 GenBank EHN00561.1 350 Pdr17p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6324065 GenBank EHN04984.1 350 Pdr17p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6324065 GenBank EJS42060.1 350 pdr17p [Saccharomyces arboricola H-6]