Gene/Proteome Database (LMPD)

LMPD ID
LMP006554
Gene ID
239759
Species
Mus musculus (Mouse)
Gene Name
lipase, member H
Gene Symbol
Liph
Synonyms
C130037N08Rik; D16Wsu119e; H06; Lpdlr; P3; PLA1B; lpd1; lpd2; mPA-PLA1
Alternate Names
lipase member H; lipase H
Chromosome
16
Map Location
16 B1|16 12.95 cM
EC Number
3.1.1.-

Proteins

lipase member H isoform 1 precursor
Refseq ID NP_001077363
Protein GI 140970704
UniProt ID Q8CIV3
mRNA ID NM_001083894
Length 451
RefSeq Status VALIDATED
MLRLCFFISFMCLVKSDTDETCPSFTRLSFHSAVVGTGLSVRLMLYTQRDQTCAQIINSTALGSLNVTKKTTFIIHGFRPTGSPPVWIEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRQVASILKEFIDQMLVKGASLDNIYMIGVSLGAHIAGFVGESYEGKLGRVTGLDPAGPLFNGRPPEERLDPSDALFVDVIHSDTDALGYKEALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVYLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGQIVPCPRVGYYADSWKEYLWDRDPPMTKAFFDTAETKPYCMYHYFVDIVSWNKSVRRGFITIKLRGEDGNITESKIDHEPSAFEKYHQVSLLARFNRDLDKVAEISLLFSTGSVVGPKYKLRVLQMKLRSLAHPDRPHLCRYDLVLMENVETSFQPILCSQQQM
lipase member H isoform 2 precursor
Refseq ID NP_700453
Protein GI 23510279
UniProt ID Q8CIV3
mRNA ID NM_153404
Length 421
RefSeq Status VALIDATED
MLRLCFFISFMCLVKSDTDETCPSFTRLSFHSAVVGTGLSVRLMLYTQRDQTCAQIINSTALGSLNVTKKTTFIIHGFRPTGSPPVWIEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRQVASILKEFIDQMLVKGASLDNIYMIGVSLGAHIAGFVGESYEGKLGRVTGLDPAGPLFNGRPPEERLDPSDALFVDVIHSDTDGIKYFKCDHQMSVYLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGQIVPCPRVGYYADSWKEYLWDRDPPMTKAFFDTAETKPYCMYHYFVDIVSWNKSVRRGFITIKLRGEDGNITESKIDHEPSAFEKYHQVSLLARFNRDLDKVAEISLLFSTGSVVGPKYKLRVLQMKLRSLAHPDRPHLCRYDLVLMENVETSFQPILCSQQQM
sig_peptide: 1..16 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1939 peptide sequence: MLRLCFFISFMCLVKS mat_peptide: 17..451 product: Lipase member H experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q8CIV3.2) calculated_mol_wt: 48755 peptide sequence: DTDETCPSFTRLSFHSAVVGTGLSVRLMLYTQRDQTCAQIINSTALGSLNVTKKTTFIIHGFRPTGSPPVWIEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRQVASILKEFIDQMLVKGASLDNIYMIGVSLGAHIAGFVGESYEGKLGRVTGLDPAGPLFNGRPPEERLDPSDALFVDVIHSDTDALGYKEALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVYLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGQIVPCPRVGYYADSWKEYLWDRDPPMTKAFFDTAETKPYCMYHYFVDIVSWNKSVRRGFITIKLRGEDGNITESKIDHEPSAFEKYHQVSLLARFNRDLDKVAEISLLFSTGSVVGPKYKLRVLQMKLRSLAHPDRPHLCRYDLVLMENVETSFQPILCSQQQM sig_peptide: 1..16 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1939 peptide sequence: MLRLCFFISFMCLVKS sig_peptide: 1..16 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1939 peptide sequence: MLRLCFFISFMCLVKS
lipase member H isoform 4 precursor
Refseq ID NP_001276511
Protein GI 575771874
UniProt ID Q8CIV3
mRNA ID NM_001289582
Length 449
RefSeq Status VALIDATED
MLRLCFFISFMCLVKSDTDETCPSFTRLSFHSAVVGTGLSVRLMLYTQRDQTCAQIINSTALGSLNVTKKTTFIIHGFRPTGSPPVWIEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRQVASILKEFIDQMLVKGASLDNIYMIGVSLGAHIAGFVGESYEGKLGRVTGLDPAGPLFNGRPPEERLDPSDALFVDVIHSDTDGYKEALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVYLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGQIVPCPRVGYYADSWKEYLWDRDPPMTKAFFDTAETKPYCMYHYFVDIVSWNKSVRRGFITIKLRGEDGNITESKIDHEPSAFEKYHQVSLLARFNRDLDKVAEISLLFSTGSVVGPKYKLRVLQMKLRSLAHPDRPHLCRYDLVLMENVETSFQPILCSQQQM

Gene Information

Entrez Gene ID
239759
Gene Name
lipase, member H
Gene Symbol
Liph
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 ISO:MGI C extracellular region
GO:0005615 IEA:Ensembl C extracellular space
GO:0005886 IEA:Ensembl C plasma membrane
GO:0008201 IEA:Ensembl F heparin binding
GO:0004620 IEA:Ensembl F phospholipase activity
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR013818 Lipase, N-terminal
IPR016272 Lipoprotein_lipase_LIPH
IPR000734 Triacylglycerol lipase family

UniProt Annotations

Entry Information

Gene Name
lipase, member H
Protein Entry
LIPH_MOUSE
UniProt ID
Q8CIV3
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8CIV3-1; Sequence=Displayed; Name=2; IsoId=Q8CIV3-2; Sequence=VSP_022506; Note=No experimental confirmation available.; Name=3; IsoId=Q8CIV3-3; Sequence=VSP_022505; Note=No experimental confirmation available.;
Function Hydrolyzes specifically phosphatidic acid (PA) to produce lysophosphatidic acid (LPA). {ECO:0000250}.
Similarity Belongs to the AB hydrolase superfamily. Lipase family. {ECO:0000305}.
Subcellular Location Secreted. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity Expressed in placenta and colon. Weakly expressed in small intestine. {ECO:0000269|PubMed:12213196}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006554 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
140970704 RefSeq NP_001077363 451 lipase member H isoform 1 precursor
23510279 RefSeq NP_700453 421 lipase member H isoform 2 precursor
575771874 RefSeq NP_001276511 449 lipase member H isoform 4 precursor

Identical Sequences to LMP006554 proteins

Reference Database Accession Length Protein Name
GI:575771874 DBBJ BAC33259.1 449 unnamed protein product [Mus musculus]
GI:140970704 DBBJ BAE22108.1 451 unnamed protein product [Mus musculus]
GI:140970704 DBBJ BAE36944.1 451 unnamed protein product [Mus musculus]
GI:23510279 GenBank AAH37489.1 421 Lipase, member H [Mus musculus]
GI:140970704 GenBank EDK97615.1 451 lipase, member H, isoform CRA_c [Mus musculus]
GI:140970704 SwissProt Q8CIV3.2 451 RecName: Full=Lipase member H; Flags: Precursor [Mus musculus]

Related Sequences to LMP006554 proteins

Reference Database Accession Length Protein Name
GI:140970704 DBBJ BAC33259.1 449 unnamed protein product [Mus musculus]
GI:23510279 DBBJ BAC33259.1 449 unnamed protein product [Mus musculus]
GI:575771874 DBBJ BAE22108.1 451 unnamed protein product [Mus musculus]
GI:140970704 DBBJ BAE36182.1 451 unnamed protein product [Mus musculus]
GI:575771874 DBBJ BAE36944.1 451 unnamed protein product [Mus musculus]
GI:23510279 DBBJ BAE36944.1 451 unnamed protein product [Mus musculus]
GI:140970704 DBBJ BAE23014.1 451 unnamed protein product [Mus musculus]
GI:140970704 GenBank AAM18804.1 451 lipase H [Mus musculus]
GI:23510279 GenBank EDK97614.1 448 lipase, member H, isoform CRA_b, partial [Mus musculus]
GI:575771874 GenBank EDK97615.1 451 lipase, member H, isoform CRA_c [Mus musculus]
GI:575771874 GenBank EDK97616.1 473 lipase, member H, isoform CRA_d, partial [Mus musculus]
GI:140970704 GenBank EDK97616.1 473 lipase, member H, isoform CRA_d, partial [Mus musculus]
GI:23510279 GenBank EDK97616.1 473 lipase, member H, isoform CRA_d, partial [Mus musculus]
GI:575771874 RefSeq NP_001077363.1 451 lipase member H isoform 1 precursor [Mus musculus]
GI:140970704 RefSeq NP_001276511.1 449 lipase member H isoform 4 precursor [Mus musculus]
GI:23510279 RefSeq NP_001276511.1 449 lipase member H isoform 4 precursor [Mus musculus]
GI:23510279 SwissProt Q8CIV3.2 451 RecName: Full=Lipase member H; Flags: Precursor [Mus musculus]
GI:575771874 SwissProt Q8CIV3.2 451 RecName: Full=Lipase member H; Flags: Precursor [Mus musculus]