Gene/Proteome Database (LMPD)

LMPD ID
LMP006163
Gene ID
56360
Species
Mus musculus (Mouse)
Gene Name
acyl-CoA thioesterase 9
Gene Symbol
Acot9
Synonyms
0610041P13Rik; Acate2; C76421; MT-ACT48; U8; p48
Alternate Names
acyl-coenzyme A thioesterase 9, mitochondrial; MTE-2; mt-ACT48.1; protein U8; acyl-CoA thioester hydrolase 9; mitochondrial acyl-CoA thioesterase; acyl coenzyme A thioester hydrolase 2; acyl-Coenzyme A thioesterase 2, mitochondrial; mitochondrial 48 kDa acyl-CoA thioester hydrolase 1
Chromosome
X
Map Location
X F3|X
EC Number
3.1.2.-

Proteins

acyl-coenzyme A thioesterase 9, mitochondrial
Refseq ID NP_062710
Protein GI 31980998
UniProt ID Q9R0X4
mRNA ID NM_019736
Length 439
RefSeq Status PROVISIONAL
MKRAAIRLWTLNKGLLTHGRGLSQGSQYKISEPLHIHQVRDKLREIVGVSTVWRDHVKAMEERKLLHSFLPKSQKVLPPRKMRDSYIEVLLPLGTDPELRDKYVTVQNTVRFGRILEDLDSLGVLVCYMHNHNHSTKMSPLSIVTVLVDKIDMCKHSLSPEQDIKFTGHVSWVGNTSMEVKMKMFQLHNDEKYWPVLDATFVMVARDSENKGPAFVNPLIPENKEEEELFKQGELNKSRRIAFSTSSLLKVAPSSEERNIIHELFLTTLDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNVFNRIFGGFLMRKAYELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQDNYIQVRVHSEVSSLDSREHMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVTLKKDYPVEP
transit_peptide: 1..21 experiment: experimental evidence, no additional details recorded note: Mitochondrion; propagated from UniProtKB/Swiss-Prot (Q9R0X4.1) calculated_mol_wt: 2393 peptide sequence: MKRAAIRLWTLNKGLLTHGRG mat_peptide: 22..439 product: Acyl-coenzyme A thioesterase 9, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q9R0X4.1) calculated_mol_wt: 48186 peptide sequence: LSQGSQYKISEPLHIHQVRDKLREIVGVSTVWRDHVKAMEERKLLHSFLPKSQKVLPPRKMRDSYIEVLLPLGTDPELRDKYVTVQNTVRFGRILEDLDSLGVLVCYMHNHNHSTKMSPLSIVTVLVDKIDMCKHSLSPEQDIKFTGHVSWVGNTSMEVKMKMFQLHNDEKYWPVLDATFVMVARDSENKGPAFVNPLIPENKEEEELFKQGELNKSRRIAFSTSSLLKVAPSSEERNIIHELFLTTLDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNVFNRIFGGFLMRKAYELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQDNYIQVRVHSEVSSLDSREHMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVTLKKDYPVEP

Gene Information

Entrez Gene ID
56360
Gene Name
acyl-CoA thioesterase 9
Gene Symbol
Acot9
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:HGNC C mitochondrion
GO:0003986 IDA:HGNC F acetyl-CoA hydrolase activity
GO:0047617 IDA:MGI F acyl-CoA hydrolase activity
GO:0052689 IEA:UniProtKB-KW F carboxylic ester hydrolase activity
GO:0006637 IDA:HGNC P acyl-CoA metabolic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5148 acyl-CoA hydrolysis

Domain Information

InterPro Annotations

Accession Description
IPR029069 HotDog domain

UniProt Annotations

Entry Information

Gene Name
acyl-CoA thioesterase 9
Protein Entry
ACOT9_MOUSE
UniProt ID
Q9R0X4
Species
Mouse

Comments

Comment Type Description
Function Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs.
Similarity Belongs to the acyl coenzyme A hydrolase family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000305|PubMed:10383425}.
Subunit Interacts with NYAP1, NYAP2 and MYO16. {ECO:0000269|PubMed:21946561}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006163 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
31980998 RefSeq NP_062710 439 acyl-coenzyme A thioesterase 9, mitochondrial

Identical Sequences to LMP006163 proteins

Reference Database Accession Length Protein Name
GI:31980998 DBBJ BAB22437.1 439 unnamed protein product [Mus musculus]
GI:31980998 DBBJ BAB26460.1 439 unnamed protein product [Mus musculus]
GI:31980998 DBBJ BAE40555.1 439 unnamed protein product [Mus musculus]
GI:31980998 DBBJ BAE42086.1 439 unnamed protein product [Mus musculus]
GI:31980998 GenBank AAH21763.1 439 Acyl-CoA thioesterase 9 [Mus musculus]
GI:31980998 GenBank EDL40846.1 439 mCG11897, isoform CRA_a [Mus musculus]

Related Sequences to LMP006163 proteins

Reference Database Accession Length Protein Name
GI:31980998 DBBJ BAA79193.1 439 U8 [Mus musculus]
GI:31980998 EMBL CAB45255.1 439 acyl-CoA thioesterase [Mus musculus]
GI:31980998 GenBank AAI08961.1 439 Acyl-CoA thioesterase 10 [Mus musculus]
GI:31980998 GenBank AAI08960.1 439 Acyl-CoA thioesterase 10 [Mus musculus]
GI:31980998 RefSeq NP_073727.2 439 acyl-coenzyme A thioesterase 10, mitochondrial precursor [Mus musculus]
GI:31980998 SwissProt Q32MW3.1 439 RecName: Full=Acyl-coenzyme A thioesterase 10, mitochondrial; Short=Acyl-CoA thioesterase 10; AltName: Full=Mitochondrial 48 kDa acyl-CoA thioester hydrolase 2; Short=Mt-ACT48.2; Flags: Precursor [Mus musculus]