Gene/Proteome Database (LMPD)

LMPD ID
LMP005897
Gene ID
51090
Species
Homo sapiens (Human)
Gene Name
plasmolipin
Gene Symbol
PLLP
Synonyms
PMLP; TM4SF11
Alternate Names
plasmolipin; plasma membrane proteolipid (plasmolipin); transmembrane 4 superfamily member 11 (plasmolipin)
Chromosome
16
Map Location
16q13

Proteins

plasmolipin
Refseq ID NP_057077
Protein GI 7705755
UniProt ID Q9Y342
mRNA ID NM_015993
Length 182
RefSeq Status VALIDATED
MAEFPSKVSTRTSSPAQGAEASVSALRPDLGFVRSRLGALMLLQLVLGLLVWALIADTPYHLYPAYGWVMFVAVFLWLVTIVLFNLYLFQLHMKLYMVPWPLVLMIFNISATVLYITAFIACSAAVDLTSLRGTRPYNQRAAASFFACLVMIAYGVSAFFSYQAWRGVGSNAATSQMAGGYA

Gene Information

Entrez Gene ID
51090
Gene Name
plasmolipin
Gene Symbol
PLLP
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0043218 IEA:Ensembl C compact myelin
GO:0070062 IDA:UniProt C extracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0045121 IEA:Ensembl C membrane raft
GO:0006811 IEA:UniProtKB-KW P ion transport
GO:0042552 IEA:Ensembl P myelination
GO:0009611 IEA:Ensembl P response to wounding

Domain Information

InterPro Annotations

Accession Description
IPR008253 Marvel domain
IPR013295 Myelin and lymphocyte (MAL) protein

UniProt Annotations

Entry Information

Gene Name
plasmolipin
Protein Entry
PLLP_HUMAN
UniProt ID
Q9Y342
Species
Human

Comments

Comment Type Description
Function Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity).
Similarity Belongs to the MAL family.
Similarity Contains 1 MARVEL domain. {ECO
Subcellular Location Membrane; Multi-pass membrane protein.
Subunit Hexamer arranged as a trimer of two plasmolipin subunits.

Identical and Related Proteins

Unique RefSeq proteins for LMP005897 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
7705755 RefSeq NP_057077 182 plasmolipin

Identical Sequences to LMP005897 proteins

Reference Database Accession Length Protein Name
GI:7705755 DBBJ BAG36633.1 182 unnamed protein product [Homo sapiens]
GI:7705755 GenBank EAW82915.1 182 plasma membrane proteolipid (plasmolipin), isoform CRA_a [Homo sapiens]
GI:7705755 GenBank EAW82917.1 182 plasma membrane proteolipid (plasmolipin), isoform CRA_a [Homo sapiens]
GI:7705755 GenBank ACQ12347.1 182 Sequence 30 from patent US 7507536
GI:7705755 GenBank ADQ32856.1 182 plasma membrane proteolipid (plasmolipin), partial [synthetic construct]
GI:7705755 GenBank AIC51392.1 182 PLLP, partial [synthetic construct]

Related Sequences to LMP005897 proteins

Reference Database Accession Length Protein Name
GI:7705755 DBBJ BAF82288.1 182 unnamed protein product [Homo sapiens]
GI:7705755 RefSeq XP_001145227.1 182 PREDICTED: plasmolipin [Pan troglodytes]
GI:7705755 RefSeq XP_002826507.1 182 PREDICTED: plasmolipin [Pongo abelii]
GI:7705755 RefSeq XP_003263143.1 182 PREDICTED: plasmolipin [Nomascus leucogenys]
GI:7705755 RefSeq XP_004057746.1 182 PREDICTED: plasmolipin [Gorilla gorilla gorilla]
GI:7705755 RefSeq XP_008975663.1 182 PREDICTED: plasmolipin [Pan paniscus]