Gene/Proteome Database (LMPD)

LMPD ID
LMP005757
Gene ID
104759
Species
Mus musculus (Mouse)
Gene Name
phospholipase D family, member 4
Gene Symbol
Pld4
Synonyms
AI132321; thss
Alternate Names
phospholipase D4; PLD 4; choline phosphatase 4; phosphatidylcholine-hydrolyzing phospholipase D4
Chromosome
12
Map Location
12 F1|12
EC Number
3.1.4.4

Proteins

phospholipase D4
Refseq ID NP_849242
Protein GI 30725764
UniProt ID Q8BG07
mRNA ID NM_178911
Length 503
RefSeq Status PROVISIONAL
MDKKKEHPEMRIPLQTAVEVSDWPCSTSHDPHSGLGMVLGMLAVLGLSSVTLILFLWQGATSFTSHRMFPEEVPSWSWETLKGDAEQQNNSCQLILVESIPEDLPFAAGSPTAQPLAQAWLQLLDTARESVHIASYYWSLTGLDIGVNDSSSRQGEALLQKFQQLLLRNISVVVATHSPTLAKTSTDLQVLAAHGAQIRQVPMKQLTGGVLHSKFWVVDGRHIYVGSANMDWRSLTQVKELGAIIYNCSNLAQDLEKTFQTYWVLGTPQAVLPKTWPRNFSSHINRFHPLRGPFDGVPTTAYFSASPPSLCPHGRTRDLDAVLGVMEGARQFIYVSVMEYFPTTRFTHHARYWPVLDNALRAAALNKGVHVRLLVSCWFNTDPTMFAYLRSLQAFSNPSAGISVDVKVFIVPVGNHSNIPFSRVNHSKFMVTDKTAYVGTSNWSEDYFSHTAGVGLIVSQKTPRAQPGATTVQEQLRQLFERDWSSHYAMDLDRQVPSQDCVW

Gene Information

Entrez Gene ID
104759
Gene Name
phospholipase D family, member 4
Gene Symbol
Pld4
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:MGI C endoplasmic reticulum
GO:0005789 TAS:Reactome C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005634 IDA:MGI C nucleus
GO:0045335 IDA:MGI C phagocytic vesicle
GO:0032588 IDA:MGI C trans-Golgi network membrane
GO:0070290 IEA:UniProtKB-EC F N-acylphosphatidylethanolamine-specific phospholipase D activity
GO:0002244 IMP:MGI P hematopoietic progenitor cell differentiation
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0006909 IMP:MGI P phagocytosis

KEGG Pathway Links

KEGG Pathway ID Description
mmu00565 Ether lipid metabolism
mmu00564 Glycerophospholipid metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
5894025 Synthesis of IP3 and IP4 in the cytosol
5893983 Synthesis of PG

Domain Information

InterPro Annotations

Accession Description
IPR001736 Phospholipase D/Transphosphatidylase

UniProt Annotations

Entry Information

Gene Name
phospholipase D family, member 4
Protein Entry
PLD4_MOUSE
UniProt ID
Q8BG07
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8BG07-1; Sequence=Displayed; Name=2; IsoId=Q8BG07-2; Sequence=VSP_023630; Note=No experimental confirmation available.;
Catalytic Activity A phosphatidylcholine + H(2)O = choline + a phosphatidate.
Sequence Caution Sequence=BAC32379.1; Type=Frameshift; Positions=443; Evidence={ECO:0000305};
Similarity Belongs to the phospholipase D family. {ECO:0000305}.
Similarity Contains 2 PLD phosphodiesterase domains. {ECO:0000255|PROSITE-ProRule:PRU00153}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP005757 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
30725764 RefSeq NP_849242 503 phospholipase D4

Identical Sequences to LMP005757 proteins

Reference Database Accession Length Protein Name
GI:30725764 DBBJ BAC37681.1 503 unnamed protein product [Mus musculus]
GI:30725764 DBBJ BAC37771.1 503 unnamed protein product [Mus musculus]
GI:30725764 GenBank EDL18583.1 503 phospholipase D family, member 4 [Mus musculus]
GI:30725764 SwissProt Q8BG07.1 503 RecName: Full=Phospholipase D4; Short=PLD 4; AltName: Full=Choline phosphatase 4; AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D4 [Mus musculus]

Related Sequences to LMP005757 proteins

Reference Database Accession Length Protein Name
GI:30725764 DBBJ BAE30496.1 495 unnamed protein product [Mus musculus]
GI:30725764 DBBJ BAE41745.1 503 unnamed protein product [Mus musculus]
GI:30725764 GenBank AAH58565.1 503 Phospholipase D family, member 4 [Mus musculus]
GI:30725764 GenBank EDL97419.1 529 similar to phospholipase D family, member 4 [Rattus norvegicus]
GI:30725764 GenBank AAI61906.1 503 Pld4 protein [Rattus norvegicus]
GI:30725764 RefSeq NP_001119760.1 529 phospholipase D4 [Rattus norvegicus]