Gene/Proteome Database (LMPD)

LMPD ID
LMP004113
Gene ID
108902
Species
Mus musculus (Mouse)
Gene Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
Gene Symbol
B3gnt1
Synonyms
1500032M01Rik; B3gnt6; BETA3GNT1; iGAT; iGNT
Alternate Names
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; I-beta-1,3-N-acetylglucosaminyltransferase; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
Chromosome
19
Map Location
19 A|19
EC Number
2.4.1.149

Proteins

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
Refseq ID NP_780592
Protein GI 30039682
UniProt ID Q8BWP8
mRNA ID NM_175383
Length 415
RefSeq Status VALIDATED
MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQYFEFFPPSPRSVDQVKSQLRTALASGGVLDASGDYRVYRGLLKTTMDPNDVILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLAYALSSHCPEMRARVAMHLVCPSRYEAAVPDPREPGEFALLRSCQEVFDKLARVAQPGINYALGTNTSYPNNLLRNLAREEANYALVIDVDMVPSEGLWRGLREMLDQSNHWDGTALVVPAFEIRRSRRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEESLLRPAYVVPWRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYRQFKQELKARYPNSPHRC

Gene Information

Entrez Gene ID
108902
Gene Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
Gene Symbol
B3gnt1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0008532 IEA:UniProtKB-EC F N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity
GO:0007411 IMP:MGI P axon guidance
GO:0030311 IEA:Ensembl P poly-N-acetyllactosamine biosynthetic process
GO:0006486 IMP:MGI P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
mmu00533 Glycosaminoglycan biosynthesis - keratan sulfate
mmu00601 Glycosphingolipid biosynthesis - lacto and neolacto series
mmu01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
5893854 Keratan sulfate biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR026603 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase

UniProt Annotations

Entry Information

Gene Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
Protein Entry
B3GN1_MOUSE
UniProt ID
Q8BWP8
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8BWP8-1; Sequence=Displayed; Name=2; IsoId=Q8BWP8-2; Sequence=VSP_014004, VSP_014005; Note=No experimental confirmation available.;
Catalytic Activity UDP-N-acetyl-D-glucosamine + beta-D- galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta- D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D- glucosaminyl-R.
Function Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans. Involved in alpha- dystroglycan (DAG1) glycosylation (By similarity). {ECO:0000250}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the glycosyltransferase 49 family. {ECO:0000305}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP004113 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
30039682 RefSeq NP_780592 415 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase

Identical Sequences to LMP004113 proteins

Reference Database Accession Length Protein Name
GI:30039682 DBBJ BAC34203.1 415 unnamed protein product [Mus musculus]
GI:30039682 DBBJ BAE34720.1 415 unnamed protein product [Mus musculus]
GI:30039682 GenBank AAH69927.1 415 B3gnt1 protein [Mus musculus]
GI:30039682 GenBank EDL33090.1 415 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1, isoform CRA_b [Mus musculus]
GI:30039682 SwissProt Q8BWP8.1 415 RecName: Full=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; AltName: Full=I-beta-1,3-N-acetylglucosaminyltransferase; Short=iGnT; AltName: Full=Poly-N-acetyllactosamine extension enzyme; AltName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 [Mus musculus]

Related Sequences to LMP004113 proteins

Reference Database Accession Length Protein Name
GI:30039682 GenBank EDM12446.1 415 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (predicted) [Rattus norvegicus]
GI:30039682 RefSeq NP_001099794.1 415 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [Rattus norvegicus]
GI:30039682 RefSeq XP_003509476.1 415 PREDICTED: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase isoform X1 [Cricetulus griseus]
GI:30039682 RefSeq XP_003749084.1 415 PREDICTED: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [Rattus norvegicus]
GI:30039682 RefSeq XP_005351760.1 415 PREDICTED: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [Microtus ochrogaster]
GI:30039682 RefSeq XP_006980646.1 415 PREDICTED: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [Peromyscus maniculatus bairdii]