Gene/Proteome Database (LMPD)

LMPD ID
LMP002936
Gene ID
108672
Species
Mus musculus (Mouse)
Gene Name
zinc finger, DHHC domain containing 15
Gene Symbol
Zdhhc15
Synonyms
6030457O13Rik
Alternate Names
palmitoyltransferase ZDHHC15; DHHC-15; zinc finger DHHC domain-containing protein 15
Chromosome
X
Map Location
X D|X
EC Number
2.3.1.225

Proteins

palmitoyltransferase ZDHHC15
Refseq ID NP_780567
Protein GI 30425060
UniProt ID Q8BGJ0
mRNA ID NM_175358
Length 337
RefSeq Status VALIDATED
MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLILYHAIFVFFAWTYWKSIFTLPQQPNQKFHLSYTDKERYKNEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRGELPSVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFTSGPEKNGFNLGFIKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMNESQNPLLANEEPWEDNEDDSRDYPEGSSSLAVESET

Gene Information

Entrez Gene ID
108672
Gene Name
zinc finger, DHHC domain containing 15
Gene Symbol
Zdhhc15
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:Ensembl C Golgi apparatus
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016409 IDA:MGI F palmitoyltransferase activity
GO:0019706 IEA:UniProtKB-EC F protein-cysteine S-palmitoyltransferase activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0045184 IDA:MGI P establishment of protein localization
GO:0018345 IDA:MGI P protein palmitoylation
GO:0016188 IMP:MGI P synaptic vesicle maturation

Domain Information

InterPro Annotations

Accession Description
IPR001594 Zinc finger, DHHC-type, palmitoyltransferase

UniProt Annotations

Entry Information

Gene Name
zinc finger, DHHC domain containing 15
Protein Entry
ZDH15_MOUSE
UniProt ID
Q8BGJ0
Species
Mouse

Comments

Comment Type Description
Catalytic Activity Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
Domain The DHHC domain is required for palmitoyltransferase activity.
Enzyme Regulation Inhibited by 2-bromopalmitate. {ECO:0000269|PubMed:15603741}.
Function Palmitoyltransferase specific for GAP43 and DLG4/PSD95. {ECO:0000269|PubMed:15603741}.
Ptm Autopalmitoylated.
Similarity Belongs to the DHHC palmitoyltransferase family. {ECO:0000305}.
Similarity Contains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed mainly in brain. {ECO:0000269|PubMed:15603741}.

Identical and Related Proteins

Unique RefSeq proteins for LMP002936 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
30425060 RefSeq NP_780567 337 palmitoyltransferase ZDHHC15

Identical Sequences to LMP002936 proteins

Reference Database Accession Length Protein Name
GI:30425060 DBBJ BAC26317.1 337 unnamed protein product [Mus musculus]
GI:30425060 DBBJ BAC37081.1 337 unnamed protein product [Mus musculus]
GI:30425060 DBBJ BAE35757.1 337 unnamed protein product [Mus musculus]
GI:30425060 GenBank AAI46424.1 337 Zinc finger, DHHC domain containing 15, partial [synthetic construct]
GI:30425060 GenBank AAI48859.1 337 Zinc finger, DHHC domain containing 15 [synthetic construct]
GI:30425060 SwissProt Q8BGJ0.1 337 RecName: Full=Palmitoyltransferase ZDHHC15; AltName: Full=Zinc finger DHHC domain-containing protein 15; Short=DHHC-15 [Mus musculus]

Related Sequences to LMP002936 proteins

Reference Database Accession Length Protein Name
GI:30425060 GenBank AAX73393.1 337 membrane-associated DHHC15 zinc finger protein [Rattus norvegicus]
GI:30425060 RefSeq NP_001034190.1 337 palmitoyltransferase ZDHHC15 [Rattus norvegicus]
GI:30425060 RefSeq XP_005086588.1 337 PREDICTED: palmitoyltransferase ZDHHC15 [Mesocricetus auratus]
GI:30425060 RefSeq XP_006257207.1 337 PREDICTED: palmitoyltransferase ZDHHC15 isoform X1 [Rattus norvegicus]
GI:30425060 RefSeq XP_006991626.1 338 PREDICTED: palmitoyltransferase ZDHHC15 [Peromyscus maniculatus bairdii]
GI:30425060 SwissProt Q2TGJ4.1 337 RecName: Full=Palmitoyltransferase ZDHHC15; AltName: Full=Zinc finger DHHC domain-containing protein 15; Short=DHHC-15 [Rattus norvegicus]