Gene/Proteome Database (LMPD)

LMPD ID
LMP002895
Gene ID
51798
Species
Mus musculus (Mouse)
Gene Name
enoyl coenzyme A hydratase 1, peroxisomal
Gene Symbol
Ech1
Synonyms
AA617331
Alternate Names
delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; dienoyl-CoA isomerase; peroxisomal/mitochondrial dienoyl-CoA isomerase
Chromosome
7
Map Location
7 A3|7
EC Number
5.3.3.-

Proteins

delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor
Refseq ID NP_058052
Protein GI 7949037
UniProt ID O35459
mRNA ID NM_016772
Length 327
RefSeq Status PROVISIONAL
MATAMTVSSKLRGLLMQQLRGTSQLYFNISLRSLSSSAQEASKRAPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASELMQPSGDDAARIAWYLRDLISKYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLVSACDIRYCTQDAFFQIKEVDMGLAADVGTLQRLPKVIGNQSLVNELTFSARKMMADEALDSGLVSRVFQDKDAMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKRDTKSITFSKL
transit_peptide: 1..33 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (Potential); propagated from UniProtKB/Swiss-Prot (O35459.1) calculated_mol_wt: 3703 peptide sequence: MATAMTVSSKLRGLLMQQLRGTSQLYFNISLRS mat_peptide: 34..327 product: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (O35459.1) calculated_mol_wt: 32433 peptide sequence: LSSSAQEASKRAPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASELMQPSGDDAARIAWYLRDLISKYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLVSACDIRYCTQDAFFQIKEVDMGLAADVGTLQRLPKVIGNQSLVNELTFSARKMMADEALDSGLVSRVFQDKDAMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKRDTKSITFSKL

Gene Information

Entrez Gene ID
51798
Gene Name
enoyl coenzyme A hydratase 1, peroxisomal
Gene Symbol
Ech1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005739 IDA:MGI C mitochondrion
GO:0005777 IEA:UniProtKB-KW C peroxisome
GO:0016853 IEA:UniProtKB-KW F isomerase activity
GO:0006635 IEA:UniProtKB-UniPathway P fatty acid beta-oxidation

KEGG Pathway Links

KEGG Pathway ID Description
ko04146 Peroxisome
mmu04146 Peroxisome

Domain Information

InterPro Annotations

Accession Description
IPR029045 ClpP/crotonase-like domain
IPR014748 Crontonase, C-terminal
IPR001753 Crotonase_core_superfam
IPR018376 Enoyl-CoA hydratase/isomerase, conserved site

UniProt Annotations

Entry Information

Gene Name
enoyl coenzyme A hydratase 1, peroxisomal
Protein Entry
ECH1_MOUSE
UniProt ID
O35459
Species
Mouse

Comments

Comment Type Description
Function Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA. {ECO:0000250}.
Pathway Lipid metabolism; fatty acid beta-oxidation.
Similarity Belongs to the enoyl-CoA hydratase/isomerase family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000250}. Peroxisome {ECO:0000250}.
Subunit Homohexamer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP002895 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
7949037 RefSeq NP_058052 327 delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor

Identical Sequences to LMP002895 proteins

Reference Database Accession Length Protein Name
GI:7949037 GenBank AAB84224.1 327 ECH1p [Mus musculus]
GI:7949037 GenBank AAH68112.1 327 Enoyl coenzyme A hydratase 1, peroxisomal [Mus musculus]
GI:7949037 GenBank AAH87924.1 327 Enoyl coenzyme A hydratase 1, peroxisomal [Mus musculus]
GI:7949037 GenBank EDL24107.1 327 enoyl coenzyme A hydratase 1, peroxisomal [Mus musculus]
GI:7949037 SwissProt O35459.1 327 RecName: Full=Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; Flags: Precursor [Mus musculus]

Related Sequences to LMP002895 proteins

Reference Database Accession Length Protein Name
GI:7949037 GenBank AAA82008.1 327 peroxisomal enoyl hydratase-like protein [Rattus norvegicus]
GI:7949037 GenBank AAH62226.1 327 Enoyl coenzyme A hydratase 1, peroxisomal [Rattus norvegicus]
GI:7949037 GenBank EDM07870.1 327 enoyl coenzyme A hydratase 1, peroxisomal [Rattus norvegicus]
GI:7949037 RefSeq NP_072116.1 327 delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor [Rattus norvegicus]
GI:7949037 RefSeq XP_006540235.1 424 PREDICTED: delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial isoform X1 [Mus musculus]
GI:7949037 SwissProt Q62651.2 327 RecName: Full=Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; Flags: Precursor [Rattus norvegicus]