Gene/Proteome Database (LMPD)

LMPD ID
LMP002828
Gene ID
30955
Species
Mus musculus (Mouse)
Gene Name
phosphoinositide-3-kinase, catalytic, gamma polypeptide
Gene Symbol
Pik3cg
Synonyms
5830428L06Rik; PI3Kgamma; p110gamma
Chromosome
12
Map Location
12|12 B

Proteins

phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Refseq ID NP_001139672
Protein GI 226246569
UniProt ID Q3UVA4
mRNA ID NM_001146200
Length 1102
RefSeq Status VALIDATED
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLHVAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLDCLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRLVTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNGDEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKIKDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDYVLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLPESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDVCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Refseq ID NP_064668
Protein GI 226246571
UniProt ID Q3UVA4
mRNA ID NM_020272
Length 1102
RefSeq Status VALIDATED
Protein sequence is identical to GI:226246569 (mRNA isoform)
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Refseq ID NP_001139673
Protein GI 226246573
UniProt ID Q3UVA4
mRNA ID NM_001146201
Length 1102
RefSeq Status VALIDATED
Protein sequence is identical to GI:226246569 (mRNA isoform)

Gene Information

Entrez Gene ID
30955
Gene Name
phosphoinositide-3-kinase, catalytic, gamma polypeptide
Gene Symbol
Pik3cg
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005942 IBA:RefGenome C phosphatidylinositol 3-kinase complex
GO:0005886 IBA:RefGenome C plasma membrane
GO:0016303 IBA:RefGenome F 1-phosphatidylinositol-3-kinase activity
GO:0035005 IBA:RefGenome F 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0046934 IBA:RefGenome F phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:2000270 IDA:MGI P negative regulation of fibroblast apoptotic process
GO:0036092 IBA:GOC P phosphatidylinositol-3-phosphate biosynthetic process
GO:0048015 IEA:InterPro P phosphatidylinositol-mediated signaling
GO:0006468 IDA:MGI P protein phosphorylation

Domain Information

InterPro Annotations

Accession Description
IPR016024 Armadillo-type fold
IPR000008 C2 domain
IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR000341 Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain
IPR003113 Phosphatidylinositol 3-kinase adaptor-binding (PI3K ABD) domain
IPR002420 Phosphatidylinositol 3-kinase, C2 domain
IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
IPR015433 Phosphatidylinositol Kinase
IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
IPR011009 Protein kinase-like domain
IPR029071 Ubiquitin-related domain

UniProt Annotations

Entry Information

Gene Name
phosphoinositide-3-kinase, catalytic, gamma polypeptide
Protein Entry
PK3CG_MOUSE
UniProt ID
Q3UVA4
Species
Mouse

Comments

Comment Type Description
Similarity Contains PI3K/PI4K domain.
Similarity Contains PIK helical domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP002828 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
226246569 RefSeq NP_001139672 1102 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

Identical Sequences to LMP002828 proteins

Reference Database Accession Length Protein Name
GI:226246569 GenBank AAH51246.1 1102 Pik3cg protein [Mus musculus]
GI:226246569 RefSeq NP_064668.2 1102 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [Mus musculus]
GI:226246569 RefSeq NP_001139673.1 1102 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [Mus musculus]
GI:226246569 RefSeq XP_006515175.1 1102 PREDICTED: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1 [Mus musculus]
GI:226246569 SwissProt Q9JHG7.2 1102 RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Short=PI3-kinase subunit gamma; Short=PI3K-gamma; Short=PI3Kgamma; Short=PtdIns-3-kinase subunit gamma; AltName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; Short=PtdIns-3-kinase subunit p110-gamma; Short=p110gamma; AltName: Full=Phosphoinositide-3-kinase catalytic gamma polypeptide; AltName: Full=Serine/threonine protein kinase PIK3CG; AltName: Full=p120-PI3K [Mus musculus]

Related Sequences to LMP002828 proteins

Reference Database Accession Length Protein Name
GI:226246569 DBBJ BAE21231.1 1102 unnamed protein product [Mus musculus]
GI:226246569 DBBJ BAE23366.1 1102 unnamed protein product [Mus musculus]
GI:226246569 GenBank ABK42313.1 1102 PI3K-p110gamma [synthetic construct]
GI:226246569 GenBank EDL36894.1 1103 phosphoinositide-3-kinase, catalytic, gamma polypeptide, isoform CRA_b, partial [Mus musculus]
GI:226246569 GenBank EDL36896.1 1102 phosphoinositide-3-kinase, catalytic, gamma polypeptide, isoform CRA_d [Mus musculus]
GI:226246569 GenBank AED45583.1 1103 Sequence 1569 from patent US 7892730