Gene/Proteome Database (LMPD)

LMPD ID
LMP002240
Gene ID
26565
Species
Mus musculus (Mouse)
Gene Name
phospholipase A2, group X
Gene Symbol
Pla2g10
Synonyms
PLA2GX; mGXsPLA2; sPLA2-X
Chromosome
16
Map Location
16 A1|16 9.5 cM

Proteins

group 10 secretory phospholipase A2 isoform 1 preproprotein
Refseq ID NP_036117
Protein GI 21356649
UniProt ID Q8C5Y6
mRNA ID NM_011987
Length 151
RefSeq Status VALIDATED
MLLLLLLLLLGPGPGFSEATRRSHVYKRGLLELAGTLDCVGPRSPMAYMNYGCYCGLGGHGEPRDAIDWCCYHHDCCYSRAQDAGCSPKLDRYPWKCMDHHILCGPAENKCQELLCRCDEELAYCLAGTEYHLKYLFFPSILCEKDSPKCN
sig_peptide: 1..17 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1767 peptide sequence: MLLLLLLLLLGPGPGFS sig_peptide: 1..17 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1767 peptide sequence: MLLLLLLLLLGPGPGFS mat_peptide: 29..151 product: Group 10 secretory phospholipase A2 experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q9QXX3.1) calculated_mol_wt: 13871 peptide sequence: GLLELAGTLDCVGPRSPMAYMNYGCYCGLGGHGEPRDAIDWCCYHHDCCYSRAQDAGCSPKLDRYPWKCMDHHILCGPAENKCQELLCRCDEELAYCLAGTEYHLKYLFFPSILCEKDSPKCN
group 10 secretory phospholipase A2 isoform 2 preproprotein
Refseq ID NP_001277938
Protein GI 597436928
UniProt ID Q8K130
mRNA ID NM_001291009
Length 144
RefSeq Status VALIDATED
MLLLLLLLLLGPGPGFSEATRRSHVYKRGLLELAGTLDCVGPRSPMAYMNYGCYCGLGGHGEPRDAIDWCCYHHDCCYSRAQDAGCSPKLDRYPWKCMDHHILCGECPMPCDFPKCPLDILQIPMAPVPLWTSREQMPRTFVQV

Gene Information

Entrez Gene ID
26565
Gene Name
phospholipase A2, group X
Gene Symbol
Pla2g10
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004623 IEA:InterPro F phospholipase A2 activity
GO:0007411 ISO:MGI P axon guidance
GO:0016042 IEA:InterPro P lipid catabolic process
GO:0051977 ISO:MGI P lysophospholipid transport
GO:0043433 IEA:Ensembl P negative regulation of sequence-specific DNA binding transcription factor activity
GO:0006644 IEA:InterPro P phospholipid metabolic process
GO:0032270 IEA:Ensembl P positive regulation of cellular protein metabolic process
GO:0010884 IEA:Ensembl P positive regulation of lipid storage
GO:0032308 IEA:Ensembl P positive regulation of prostaglandin secretion
GO:0043030 IEA:Ensembl P regulation of macrophage activation

Domain Information

InterPro Annotations

Accession Description
IPR001211 Phospholipase A2
IPR016090 Phospholipase A2 domain
IPR013090 Phospholipase A2, active site

UniProt Annotations

Entry Information

Gene Name
phospholipase A2, group X
Protein Entry
Q8K130_MOUSE
UniProt ID
Q8K130
Species
Mouse

Comments

Comment Type Description
Catalytic Activity Phosphatidylcholine + H(2)O = 1- acylglycerophosphocholine + a carboxylate.
Cofactor Note=Binds 1 calcium ion per subunit. ;
Similarity Belongs to the phospholipase A2 family.
Subcellular Location Secreted .

Identical and Related Proteins

Unique RefSeq proteins for LMP002240 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
21356649 RefSeq NP_036117 151 group 10 secretory phospholipase A2 isoform 1 preproprotein
597436928 RefSeq NP_001277938 144 group 10 secretory phospholipase A2 isoform 2 preproprotein

Identical Sequences to LMP002240 proteins

Reference Database Accession Length Protein Name
GI:21356649 GenBank AAF04498.2 151 group X secreted phospholipase A2 [Mus musculus]
GI:597436928 GenBank AAH28879.1 144 Pla2g10 protein [Mus musculus]
GI:597436928 GenBank EDK97369.1 144 phospholipase A2, group X, isoform CRA_a [Mus musculus]
GI:21356649 GenBank EDK97370.1 151 phospholipase A2, group X, isoform CRA_b [Mus musculus]
GI:21356649 GenBank AEU43280.1 151 Sequence 29 from patent US 8052970
GI:21356649 SwissProt Q9QXX3.1 151 RecName: Full=Group 10 secretory phospholipase A2; AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10; Flags: Precursor [Mus musculus]

Related Sequences to LMP002240 proteins

Reference Database Accession Length Protein Name
GI:21356649 DBBJ BAC36530.1 141 unnamed protein product, partial [Mus musculus]
GI:597436928 GenBank AAF04498.2 151 group X secreted phospholipase A2 [Mus musculus]
GI:597436928 GenBank AAG43522.1 151 group X secretory phospholipase A2 [Mus musculus]
GI:21356649 GenBank AAG43522.1 151 group X secretory phospholipase A2 [Mus musculus]
GI:597436928 GenBank EDK97370.1 151 phospholipase A2, group X, isoform CRA_b [Mus musculus]
GI:597436928 GenBank AEU43280.1 151 Sequence 29 from patent US 8052970
GI:21356649 GenBank AEU43300.1 151 Sequence 49 from patent US 8052970
GI:21356649 GenBank AEU43336.1 151 Sequence 85 from patent US 8052970
GI:21356649 GenBank AGO77664.1 151 Sequence 22 from patent US 8399204
GI:21356649 RefSeq NP_058872.1 151 group 10 secretory phospholipase A2 precursor [Rattus norvegicus]
GI:597436928 RefSeq NP_036117.1 151 group 10 secretory phospholipase A2 isoform 1 preproprotein [Mus musculus]
GI:597436928 SwissProt Q9QXX3.1 151 RecName: Full=Group 10 secretory phospholipase A2; AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10; Flags: Precursor [Mus musculus]