Gene/Proteome Database (LMPD)

LMPD ID
LMP002042
Gene ID
227333
Species
Mus musculus (Mouse)
Gene Name
diacylglycerol kinase, delta
Gene Symbol
Dgkd
Synonyms
AI841987; D330025K09; DGKdelta; dgkd-2
Chromosome
1
Map Location
1 D|1

Proteins

diacylglycerol kinase, delta
Refseq ID NP_808314
Protein GI 221139790
UniProt ID E9PUQ8
mRNA ID NM_177646
Length 1220
RefSeq Status VALIDATED
MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTILKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNKEHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREVLSGVTSHGLSCEVCKFKAHKRCAVRATSNCKWTTLASIGKDIIEDEDGIAMPHQWLEGNLPVSAKCIVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLVMKCPLGLCKVSVIPPTALNSIDSDGFWKATCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILAKLERASTKMLDRWSVMAYETKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSQESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLSNPPPTIAEEAEDGDGSGNICSSTGDHLVGSACPSRPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQQGFVLGLSESEKKDLKTDNRVCTSSVHSESCVIAKGRSQRKASRAPCEKLVSKGLSLGSSASLPPGTGSRDSLPALNTKILYPSVRAGMSGSLPGGSVISRLLINADPFNAEPENLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYRNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIKLQHHRIAQCRTVKISILGDEGVPVQVDGEAWIQPPGYIRIVHKNRAQTLTRDRAFENTLKSWEDKQKCELSRPPSFSLHPEILSEEEATQMDQFGQAAGGLIHSIREIAQSHRAMEQELAHAVNASSKAMERVYGKPRTAEGLNCSFVLEMVNNIRALRSETELLLAGKMALQLDPPQKERLGAALIEMDQQLRKLTDTPWLCQPLEPGEEESLQQNVMLDLTKRSRSGKFRLVTKFKKEKNNKNKEVHSNLGGPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSSPAAEA

Gene Information

Entrez Gene ID
227333
Gene Name
diacylglycerol kinase, delta
Gene Symbol
Dgkd
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016023 IEA:Ensembl C cytoplasmic membrane-bounded vesicle
GO:0005886 IEA:Ensembl C plasma membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0003951 IEA:InterPro F NAD+ kinase activity
GO:0004143 IEA:UniProtKB-EC F diacylglycerol kinase activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0051260 IEA:Ensembl P protein homooligomerization
GO:0007205 IEA:InterPro P protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0010033 IEA:Ensembl P response to organic substance

Domain Information

InterPro Annotations

Accession Description
IPR016064 ATP-NAD kinase-like domain
IPR000756 Diacylglycerol kinase, accessory domain
IPR001206 Diacylglycerol kinase, catalytic domain
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR001660 Sterile alpha motif domain
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain

UniProt Annotations

Entry Information

Gene Name
diacylglycerol kinase, delta
Protein Entry
E9PUQ8_MOUSE
UniProt ID
E9PUQ8
Species
Mouse

Comments

Comment Type Description
Catalytic Activity ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2- diacyl-sn-glycerol 3-phosphate.
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Belongs to the eukaryotic diacylglycerol kinase family.
Similarity Contains 1 DAGKc domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 SAM (sterile alpha motif) domain.
Similarity Contains 2 phorbol-ester/DAG-type zinc fingers.
Similarity Contains PH domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP002042 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
221139790 RefSeq NP_808314 1220 diacylglycerol kinase, delta

Identical Sequences to LMP002042 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP002042 proteins

Reference Database Accession Length Protein Name
GI:221139790 GenBank EDL40135.1 1168 mCG131116, isoform CRA_a, partial [Mus musculus]
GI:221139790 RefSeq XP_005361784.1 1226 PREDICTED: diacylglycerol kinase delta isoform X1 [Microtus ochrogaster]
GI:221139790 RefSeq XP_005361785.1 1216 PREDICTED: diacylglycerol kinase delta isoform X2 [Microtus ochrogaster]
GI:221139790 RefSeq XP_006226999.1 1169 PREDICTED: diacylglycerol kinase delta isoform X3 [Rattus norvegicus]
GI:221139790 RefSeq XP_006529534.1 1227 PREDICTED: diacylglycerol kinase, delta isoform X1 [Mus musculus]
GI:221139790 RefSeq XP_006245566.2 1204 PREDICTED: diacylglycerol kinase delta isoform X4 [Rattus norvegicus]