Gene/Proteome Database (LMPD)

LMPD ID
LMP002000
Gene ID
19220
Species
Mus musculus (Mouse)
Gene Name
prostaglandin F receptor
Gene Symbol
Ptgfr
Synonyms
AI957154; PGF; fp
Alternate Names
prostaglandin F2-alpha receptor; PGF receptor; PGF2-alpha receptor; prostanoid FP receptor; prostaglandin F2alpha receptor
Chromosome
3
Map Location
3 H3|3 76.96 cM

Proteins

prostaglandin F2-alpha receptor
Refseq ID NP_032992
Protein GI 6679533
UniProt ID P43117
mRNA ID NM_008966
Length 366
RefSeq Status VALIDATED
MSMNSSKQPVSPAAGLIANTTCQTENRLSVFFSIIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSIFGISMVFSGLCPLFLGSAMAIERCIGVTNPIFHSTKITSKHVKMILSGVCMFAVFVAVLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSFLGLLALGVSFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMIIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKESQQASSEAGL

Gene Information

Entrez Gene ID
19220
Gene Name
prostaglandin F receptor
Gene Symbol
Ptgfr
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:Ensembl C cytoplasm
GO:0005576 IEA:Ensembl C extracellular region
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:0004958 IEA:Ensembl F prostaglandin F receptor activity
GO:0035584 IEA:Ensembl P calcium-mediated signaling using intracellular calcium source
GO:0043066 IMP:MGI P negative regulation of apoptotic process
GO:0032496 IMP:MGI P response to lipopolysaccharide

KEGG Pathway Links

KEGG Pathway ID Description
mmu04020 Calcium signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID Description
5893712 Prostanoid ligand receptors

Domain Information

InterPro Annotations

Accession Description
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
IPR001244 Prostaglandin DP receptor
IPR000141 Prostaglandin F receptor
IPR008365 Prostanoid receptor

UniProt Annotations

Entry Information

Gene Name
prostaglandin F receptor
Protein Entry
PF2R_MOUSE
UniProt ID
P43117
Species
Mouse

Comments

Comment Type Description
Function Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). {ECO:0000250}.
Similarity Belongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular Location Cell membrane; Multi-pass membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP002000 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6679533 RefSeq NP_032992 366 prostaglandin F2-alpha receptor

Identical Sequences to LMP002000 proteins

Reference Database Accession Length Protein Name
GI:6679533 DBBJ BAC80245.1 366 prostaglandin F2alpha receptor [Mus musculus]
GI:6679533 DBBJ BAC80246.1 366 prostaglandin F2alpha receptor [Mus musculus]
GI:6679533 DBBJ BAE24824.1 366 unnamed protein product [Mus musculus]
GI:6679533 GenBank AAH64794.1 366 Prostaglandin F receptor [Mus musculus]
GI:6679533 GenBank EDL11940.1 366 prostaglandin F receptor, isoform CRA_a [Mus musculus]
GI:6679533 GenBank EDL11941.1 366 prostaglandin F receptor, isoform CRA_a [Mus musculus]

Related Sequences to LMP002000 proteins

Reference Database Accession Length Protein Name
GI:6679533 DBBJ BAB29498.1 366 unnamed protein product [Mus musculus]
GI:6679533 EMBL CAA58736.1 366 F2alpha receptor [Rattus norvegicus]
GI:6679533 GenBank AAB32739.1 366 prostaglandin F2 alpha receptor [Rattus sp.]
GI:6679533 GenBank AAB19233.1 366 prostaglandin F2a receptor [Rattus norvegicus]
GI:6679533 pat US 366 Sequence 50 from patent US 5747660
GI:6679533 SwissProt P43118.1 366 RecName: Full=Prostaglandin F2-alpha receptor; Short=PGF receptor; Short=PGF2-alpha receptor; AltName: Full=Prostanoid FP receptor [Rattus norvegicus]