Gene/Proteome Database (LMPD)

LMPD ID
LMP001586
Gene ID
22234
Species
Mus musculus (Mouse)
Gene Name
UDP-glucose ceramide glucosyltransferase
Gene Symbol
Ugcg
Synonyms
AU043821; C80537; Epcs21; GlcT-1; Ugcgl
Chromosome
4
Map Location
4 B3|4 32.44 cM

Proteins

ceramide glucosyltransferase
Refseq ID NP_035803
Protein GI 7106443
UniProt ID O88693
mRNA ID NM_011673
Length 394
RefSeq Status PROVISIONAL
MALLDLAQEGMALFGFVLFVVLWLMHFMSIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPAYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFSMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV

Gene Information

Entrez Gene ID
22234
Gene Name
UDP-glucose ceramide glucosyltransferase
Gene Symbol
Ugcg
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0008120 IEA:UniProtKB-EC F ceramide glucosyltransferase activity
GO:0006665 IEA:UniProtKB-UniPathway P sphingolipid metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR025993 Ceramide glucosyltransferase
IPR029044 Nucleotide-diphospho-sugar transferases

UniProt Annotations

Entry Information

Gene Name
UDP-glucose ceramide glucosyltransferase
Protein Entry
O88693_MOUSE
UniProt ID
O88693
Species
Mouse

Comments

Comment Type Description
Catalytic Activity UDP-glucose + N-acylsphingosine = UDP + D- glucosyl-N-acylsphingosine.
Function Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase" (By similarity).
Pathway Lipid metabolism; sphingolipid metabolism.
Similarity Belongs to the glycosyltransferase 2 family.
Subcellular Location Golgi apparatus membrane ; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP001586 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
7106443 RefSeq NP_035803 394 ceramide glucosyltransferase

Identical Sequences to LMP001586 proteins

Reference Database Accession Length Protein Name
GI:7106443 DBBJ BAA28782.1 394 ceramide glucosyltransferase [Mus musculus]
GI:7106443 DBBJ BAA33558.1 394 UDP-glucose ceramide glucosyltransferase [Mus musculus]
GI:7106443 GenBank AAH50828.1 394 UDP-glucose ceramide glucosyltransferase [Mus musculus]
GI:7106443 GenBank EDL02214.1 394 UDP-glucose ceramide glucosyltransferase [Mus musculus]
GI:7106443 SwissProt O88693.1 394 RecName: Full=Ceramide glucosyltransferase; AltName: Full=GLCT-1; AltName: Full=Glucosylceramide synthase; Short=GCS; AltName: Full=UDP-glucose ceramide glucosyltransferase; AltName: Full=UDP-glucose:N-acylsphingosine D-glucosyltransferase [Mus musculus]

Related Sequences to LMP001586 proteins

Reference Database Accession Length Protein Name
GI:7106443 GenBank AAD02464.1 394 UDP-glucose:ceramide glycosyltransferase [Rattus norvegicus]
GI:7106443 GenBank AAK29448.1 394 ceramide glucosyltransferase [Cricetulus griseus]
GI:7106443 RefSeq NP_001233621.1 394 ceramide glucosyltransferase [Cricetulus griseus]
GI:7106443 RefSeq XP_005362291.1 394 PREDICTED: ceramide glucosyltransferase [Microtus ochrogaster]
GI:7106443 RefSeq XP_006994083.1 394 PREDICTED: ceramide glucosyltransferase [Peromyscus maniculatus bairdii]
GI:7106443 RefSeq XP_008829351.1 394 PREDICTED: ceramide glucosyltransferase [Nannospalax galili]