Gene/Proteome Database (LMPD)

LMPD ID
LMP000993
Gene ID
18711
Species
Mus musculus (Mouse)
Gene Name
phosphoinositide kinase, FYVE finger containing
Gene Symbol
Pikfyve
Synonyms
5230400C17Rik; Pip5k; Pip5k3; Pipk5k3; PipkIII; p235
Chromosome
1
Map Location
1 C2|1

Proteins

1-phosphatidylinositol 3-phosphate 5-kinase
Refseq ID NP_035216
Protein GI 115529473
UniProt ID Q9Z1T6
mRNA ID NM_011086
Length 2052
RefSeq Status VALIDATED
MATDDKSSPTLDSANDLPRSPASPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERGEGGQGEQQSPSSSWASPQIPSRTQSVRSPVPYKKQLNEELHRRSSVLENTLPHPQESTDSRRKAEPACGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSTCSVSILDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNSALSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRNYIRTETTEDERKILLDSAQLKDLWKKICHHTSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLAKYLVSDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENEEKQAMERLLSANHNHMMALLQQLLQNESLSSSWRDIIVSLVCQVVQTVRPDVKHQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMNSCIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVVSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQSPSFHLLTEGRGEEGASQEQVSGSSLPQDPECPREALSSEDSTLLESRTVLEKGELDNKSIPQAVASLKHQDYTTPTCPAGIPCALFALVPESLLPLHMDQQDAVGNEQPETSQQTDEQQDPKSQMKAFRDPLQDDTGMYVTEEVTSSEDQRKTYALTFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYFPEQIYWSPLLNKEVKEMESRRKKQLLRDLSGLQGMNGSVQAKSIQVLPSHELVSTRIAEHLGDSQTLGRMLADYRARGGRIQSKHLDPFVHSKDASCTSGGKSGNKTESDEERGLIPSDVIWPTKVDCLNPANHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERYCFRSSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYLAVDERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKNWTEKMQARLMSSSVDTPQQLQSIFESLIAKKQSLCEVLQAWNSRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKINAMDTSPRNISPGLHNGEKEDRFLTTLSSQSSTSSTHLQLPTPPEALAEQVVGGPTDLDSASGSEDVFDGHLLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYRNALEELSKATLRNSAEEGLPANSALDNRPKSSSPIRLPEISGGQTNRTVEAEPQPTKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQAGKEGLESQGLEPQDEVDGGDTQKKQLTNPHVELQFSDANAKFYCRLYYAGEFHKMREVILGSSEEEFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKSVLRTSIHSDAHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLDLNC

Gene Information

Entrez Gene ID
18711
Gene Name
phosphoinositide kinase, FYVE finger containing
Gene Symbol
Pikfyve
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005911 IDA:MGI C cell-cell junction
GO:0031410 IDA:MGI C cytoplasmic vesicle
GO:0005829 IDA:MGI C cytosol
GO:0048471 IDA:MGI C perinuclear region of cytoplasm
GO:0005524 IEA:InterPro F ATP binding
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0016307 IEA:InterPro F phosphatidylinositol phosphate kinase activity
GO:0044267 IEA:InterPro P cellular protein metabolic process
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0032288 IGI:MGI P myelin assembly

Domain Information

InterPro Annotations

Accession Description
IPR002423 Chaperonin Cpn60/TCP-1
IPR000591 DEP domain
IPR000306 FYVE zinc finger
IPR027409 GroEL-like apical domain
IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain
IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
IPR027410 TCP-1-like chaperonin intermediate domain
IPR011991 Winged helix-turn-helix DNA-binding domain
IPR017455 Zinc finger, FYVE-related
IPR011011 Zinc finger, FYVE/PHD-type
IPR013083 Zinc finger, RING/FYVE/PHD-type

UniProt Annotations

Entry Information

Gene Name
phosphoinositide kinase, FYVE finger containing
Protein Entry
FYV1_MOUSE
UniProt ID
Q9Z1T6
Species
Mouse

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Contains PIPK domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP000993 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
115529473 RefSeq NP_035216 2052 1-phosphatidylinositol 3-phosphate 5-kinase

Identical Sequences to LMP000993 proteins

Reference Database Accession Length Protein Name
GI:115529473 GenBank AAI48368.1 2052 Phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III, partial [synthetic construct]

Related Sequences to LMP000993 proteins

Reference Database Accession Length Protein Name
GI:115529473 GenBank EDL98860.1 2052 similar to phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III isoform 2 [Rattus norvegicus]
GI:115529473 RefSeq XP_006226923.1 2073 PREDICTED: 1-phosphatidylinositol 3-phosphate 5-kinase isoform X5 [Rattus norvegicus]
GI:115529473 RefSeq XP_006226924.1 2072 PREDICTED: 1-phosphatidylinositol 3-phosphate 5-kinase isoform X6 [Rattus norvegicus]
GI:115529473 RefSeq XP_006245140.1 2073 PREDICTED: 1-phosphatidylinositol 3-phosphate 5-kinase isoform X5 [Rattus norvegicus]
GI:115529473 RefSeq XP_006245141.1 2072 PREDICTED: 1-phosphatidylinositol 3-phosphate 5-kinase isoform X6 [Rattus norvegicus]
GI:115529473 RefSeq XP_006495845.1 2053 PREDICTED: 1-phosphatidylinositol 3-phosphate 5-kinase isoform X7 [Mus musculus]