Gene/Proteome Database (LMPD)

LMPD ID
LMP000806
Gene ID
69217
Species
Mus musculus (Mouse)
Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
Gene Symbol
Plekha4
Synonyms
2410005C22Rik; C88169; Pepp1
Chromosome
7
Map Location
7 B4|7

Proteins

pleckstrin homology domain-containing family A member 4
Refseq ID NP_683729
Protein GI 158187513
UniProt ID D3Z3Y7
mRNA ID NM_148927
Length 779
RefSeq Status VALIDATED
MEQGRPRSSLSLASSASTVSSLSSLSTKKPTRAVHKVHAFGKRNNALRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYSVRPDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGEDCGLPRSPARPRPGEGPGGPGGPPEVNRREEGRISESPEVARLSRGLGRHETHTPNSTVDLQTDTWSRRTRSPELFSPLSRPPSPLSLPRPRSAPARRPPLSAGDISFPARPHTPLSRIDVRPPLDWGPQRQTLSRPPIPRRGPSSEAGGERPPRSPQPRTPEQRTQSTQATSGSSTYLQLPPRPPGTQASMILLPGPPVDSALHQSLETDTLLTKLCGQDRLLRQLQEDLDKRQEEKEQLEAALELTRQQLGQATREAAASGKAWGRQRLLQDRLVNVRAALCHLAQERERVWDTYSGLEQDLGTLRETLEYLLHLGSPQDRACAQQQLWMVEDTLAGLGGPQKQPPHTDPKSPSPAPQGEESSERESLSESLELSSPQSPEVDWSRPSGGDRALSSPQSGVGSPRVSRASSPECRQPSSPLLRTKAPLARPRMSAQEQLERMRRNQACGLPLPRPTSPRLLTLGRTLSPAPRQPDMEQRPIVGAAKWLRSSGSWSSPRHSATCSPVPGGHRERVLSLSQALATEASQWHRLMAASPGRNLDTRGDCLQPSPQPPSEELPQVTSSPAPHKATSATTGFSCQGSRRGLAPWEARWDPGKAPPALTQEEGAWPFRVTLLQSSF

Gene Information

Entrez Gene ID
69217
Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
Gene Symbol
Plekha4
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0008289 IEA:UniProtKB-KW F lipid binding

Domain Information

InterPro Annotations

Accession Description
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
Protein Entry
D3Z3Y7_MOUSE
UniProt ID
D3Z3Y7
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8VC98-1; Sequence=Displayed; Name=2; IsoId=Q8VC98-2; Sequence=VSP_009773, VSP_009774; Note=No experimental confirmation available.;
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Function Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. {ECO:0000250}.
Similarity Contains 1 PH domain.
Similarity Contains 1 PH domain. {ECO:0000255|PROSITE- ProRule:PRU00145}.
Subcellular Location Cytoplasm {ECO:0000305}. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP000806 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
158187513 RefSeq NP_683729 779 pleckstrin homology domain-containing family A member 4

Identical Sequences to LMP000806 proteins

Reference Database Accession Length Protein Name
GI:158187513 RefSeq XP_006541225.1 779 PREDICTED: pleckstrin homology domain-containing family A member 4 isoform X5 [Mus musculus]
GI:158187513 RefSeq XP_006541226.1 779 PREDICTED: pleckstrin homology domain-containing family A member 4 isoform X6 [Mus musculus]

Related Sequences to LMP000806 proteins

Reference Database Accession Length Protein Name
GI:158187513 RefSeq NP_954532.1 779 pleckstrin homology domain-containing family A member 4 [Rattus norvegicus]
GI:158187513 RefSeq XP_006541221.1 831 PREDICTED: pleckstrin homology domain-containing family A member 4 isoform X1 [Mus musculus]
GI:158187513 RefSeq XP_006541222.1 819 PREDICTED: pleckstrin homology domain-containing family A member 4 isoform X2 [Mus musculus]
GI:158187513 RefSeq XP_006541223.1 815 PREDICTED: pleckstrin homology domain-containing family A member 4 isoform X3 [Mus musculus]
GI:158187513 RefSeq XP_006541224.1 794 PREDICTED: pleckstrin homology domain-containing family A member 4 isoform X4 [Mus musculus]
GI:158187513 SwissProt P60669.1 779 RecName: Full=Pleckstrin homology domain-containing family A member 4; Short=PH domain-containing family A member 4; AltName: Full=Phosphoinositol 3-phosphate-binding protein 1; Short=PEPP-1 [Rattus norvegicus]