Gene/Proteome Database (LMPD)

LMPD ID
LMP000470
Gene ID
70546
Species
Mus musculus (Mouse)
Gene Name
zinc finger, DHHC domain containing 2
Gene Symbol
Zdhhc2
Synonyms
5730415P04Rik; 6430583A19Rik
Alternate Names
palmitoyltransferase ZDHHC2; DHHC-2; zinc finger DHHC domain-containing protein 2
Chromosome
8
Map Location
8 A4|8
EC Number
2.3.1.225

Proteins

palmitoyltransferase ZDHHC2
Refseq ID NP_848482
Protein GI 30409974
UniProt ID P59267
mRNA ID NM_178395
Length 366
RefSeq Status PROVISIONAL
MAPSGSGGVRRRCRRVLYWIPVVFISLLLGWSYYAYAIQLCIVSMENIGEQVVCLMAYHLLFAMFVWSYWKTIFTLPMNPSKEFHLSYAEKELLEREPRGEAHQEVLRRAAKDLPIYTRTMSGAIRYCDRCQLIKPDRCHHCSVCDKCILKMDHHCPWVNNCVGFSNYKFFLLFLAYSLLYCLFIAATDLQYFIRFWTNGLPDTQAKFHIMFLFFAAAMFSVSLSSLFGYHCWLVSKNKSTLEAFRNPVFRHGTDKNGFSLGFSKNMRQVFGDEKKYWLLPVFSSQGDGCSFPTCLVNQDPEQPSTPAGLNSTVKNPENHQFPAKPLRESQSHLLKDSQTWTESSANPGKGKAGMSNPALTMENET

Gene Information

Entrez Gene ID
70546
Gene Name
zinc finger, DHHC domain containing 2
Gene Symbol
Zdhhc2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:Ensembl C Golgi apparatus
GO:0005783 IEA:Ensembl C endoplasmic reticulum
GO:0005887 IDA:MGI C integral component of plasma membrane
GO:0055038 IDA:MGI C recycling endosome membrane
GO:0016409 IDA:MGI F palmitoyltransferase activity
GO:0019706 IEA:UniProtKB-EC F protein-cysteine S-palmitoyltransferase activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0018345 IDA:MGI P protein palmitoylation

Domain Information

InterPro Annotations

Accession Description
IPR001594 Zinc finger, DHHC-type, palmitoyltransferase

UniProt Annotations

Entry Information

Gene Name
zinc finger, DHHC domain containing 2
Protein Entry
ZDHC2_MOUSE
UniProt ID
P59267
Species
Mouse

Comments

Comment Type Description
Catalytic Activity Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
Domain The DHHC domain is required for palmitoyltransferase activity. {ECO:0000250}.
Function Palmitoyltransferase specific for GAP43 and DLG4/PSD95. {ECO:0000269|PubMed:15603741}.
Similarity Belongs to the DHHC palmitoyltransferase family. {ECO:0000305}.
Similarity Contains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in all brain regions. {ECO:0000269|PubMed:15603741}.

Identical and Related Proteins

Unique RefSeq proteins for LMP000470 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
30409974 RefSeq NP_848482 366 palmitoyltransferase ZDHHC2

Identical Sequences to LMP000470 proteins

Reference Database Accession Length Protein Name
GI:30409974 DBBJ BAC27068.1 366 unnamed protein product [Mus musculus]
GI:30409974 EMBL CBY79707.1 366 unnamed protein product [Mus musculus]
GI:30409974 RefSeq XP_006509548.1 366 PREDICTED: palmitoyltransferase ZDHHC2 isoform X1 [Mus musculus]
GI:30409974 RefSeq XP_006509549.1 366 PREDICTED: palmitoyltransferase ZDHHC2 isoform X2 [Mus musculus]
GI:30409974 SwissProt P59267.1 366 RecName: Full=Palmitoyltransferase ZDHHC2; AltName: Full=Zinc finger DHHC domain-containing protein 2; Short=DHHC-2 [Mus musculus]

Related Sequences to LMP000470 proteins

Reference Database Accession Length Protein Name
GI:30409974 DBBJ BAF37828.1 366 DHHC2 [Rattus norvegicus]
GI:30409974 GenBank AAF43032.1 366 small rec [Rattus norvegicus]
GI:30409974 GenBank AAI27157.1 366 Zinc finger, DHHC domain containing 2 [Mus musculus]
GI:30409974 RefSeq XP_005066698.1 371 PREDICTED: palmitoyltransferase ZDHHC2 [Mesocricetus auratus]
GI:30409974 RefSeq XP_005362596.1 366 PREDICTED: palmitoyltransferase ZDHHC2 [Microtus ochrogaster]
GI:30409974 SwissProt Q9JKR5.1 366 RecName: Full=Palmitoyltransferase ZDHHC2; AltName: Full=Zinc finger DHHC domain-containing protein 2; Short=DHHC-2 [Rattus norvegicus]