Gene/Proteome Database (LMPD)

LMPD ID
LMP000409
Gene ID
16329
Species
Mus musculus (Mouse)
Gene Name
inositol polyphosphate-1-phosphatase
Gene Symbol
Inpp1
Synonyms
2300002C06Rik; AV137389
Alternate Names
inositol polyphosphate 1-phosphatase; IPP; IPPase
Chromosome
1
Map Location
1 C1.1|1 26.99 cM
EC Number
3.1.3.57

Proteins

inositol polyphosphate 1-phosphatase
Refseq ID NP_032410
Protein GI 170650609
UniProt ID P49442
mRNA ID NM_008384
Length 396
RefSeq Status VALIDATED
MSDILLELLCVSEKAANIARACRQQETLFQLLIEEKKGAEKNKKFAADFKTLADVLVQEVIKQNMENKFPGLGKKVFGEESNEFTNDLGEKITVELQSTEEETAELLSKVLNGNMPASEALAQVVHEDVDLTDPTLESLDISIPHESLGIWVDPIDSTYQYIKGSANVKSNQGIFPSGLQCVTILIGVYDLQTGLPLMGVINQPFASQNLTTLRWKGQCYWGLSYMGTNIHSLQLAISKSDSETQTENSDREFSSPFSAVISTSEKDTIKAALSRVCGGSVFPAAGAGYKSLCVIQGLADIYIFSEDTTYKWDSCAAHAILRAMGGGIVDMKECLERSPDTGLDLPQLLYHVENKGASGVELWANKGGLIAYRSRNRLDTFLSRLIQNLGPVKTQA

Gene Information

Entrez Gene ID
16329
Gene Name
inositol polyphosphate-1-phosphatase
Gene Symbol
Inpp1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0004441 IEA:UniProtKB-EC F inositol-1,4-bisphosphate 1-phosphatase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0046854 IEA:InterPro P phosphatidylinositol phosphorylation

KEGG Pathway Links

KEGG Pathway ID Description
mmu00562 Inositol phosphate metabolism
mmu01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
5894027 Synthesis of IP2, IP, and Ins in the cytosol

Domain Information

InterPro Annotations

Accession Description
IPR020550 Inositol monophosphatase, conserved site
IPR020583 Inositol monophosphatase, metal-binding site
IPR000760 Inositol_monophosphatase

UniProt Annotations

Entry Information

Gene Name
inositol polyphosphate-1-phosphatase
Protein Entry
INPP_MOUSE
UniProt ID
P49442
Species
Mouse

Comments

Comment Type Description
Catalytic Activity 1D-myo-inositol 1,4-bisphosphate + H(2)O = 1D- myo-inositol 4-phosphate + phosphate.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
Enzyme Regulation Inhibited by Li(+). {ECO:0000250}.
Pathway Signal transduction; phosphatidylinositol signaling pathway.
Similarity Belongs to the inositol monophosphatase family. {ECO:0000305}.
Subunit Monomer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP000409 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
170650609 RefSeq NP_032410 396 inositol polyphosphate 1-phosphatase

Identical Sequences to LMP000409 proteins

Reference Database Accession Length Protein Name
GI:170650609 DBBJ BAC37245.1 396 unnamed protein product [Mus musculus]
GI:170650609 GenBank AAH25072.1 396 Inositol polyphosphate-1-phosphatase [Mus musculus]
GI:170650609 GenBank EDK99980.1 396 inositol polyphosphate-1-phosphatase [Mus musculus]
GI:170650609 RefSeq XP_006495798.1 396 PREDICTED: inositol polyphosphate 1-phosphatase isoform X1 [Mus musculus]
GI:170650609 RefSeq XP_006495799.1 396 PREDICTED: inositol polyphosphate 1-phosphatase isoform X2 [Mus musculus]
GI:170650609 SwissProt P49442.2 396 RecName: Full=Inositol polyphosphate 1-phosphatase; Short=IPP; Short=IPPase [Mus musculus]

Related Sequences to LMP000409 proteins

Reference Database Accession Length Protein Name
GI:170650609 GenBank AAA97574.1 396 inositol polyphosphate 1-phosphatase [Mus musculus]
GI:170650609 GenBank AAH86600.1 396 Inositol polyphosphate-1-phosphatase [Rattus norvegicus]
GI:170650609 GenBank EDL99104.1 396 rCG22563 [Rattus norvegicus]
GI:170650609 RefSeq NP_001012131.1 396 inositol polyphosphate 1-phosphatase [Rattus norvegicus]
GI:170650609 RefSeq XP_008765313.1 396 PREDICTED: inositol polyphosphate 1-phosphatase isoform X1 [Rattus norvegicus]
GI:170650609 RefSeq XP_008765314.1 396 PREDICTED: inositol polyphosphate 1-phosphatase isoform X1 [Rattus norvegicus]