Gene/Proteome Database (LMPD)

LMPD ID
LMP000357
Gene ID
112406
Species
Mus musculus (Mouse)
Gene Name
egl-9 family hypoxia-inducible factor 2
Gene Symbol
Egln2
Synonyms
0610011A13Rik; C85656; Hif-p4h-1; Ier4; Phd1; SM-20
Chromosome
7
Map Location
7 A3|7 15.83 cM

Proteins

egl nine homolog 2
Refseq ID NP_444438
Protein GI 21450783
UniProt ID Q80X29
mRNA ID NM_053208
Length 419
RefSeq Status VALIDATED
MDSPCQPQALNQALPQLPGSVSESLESSRARMGVESYLPCPLLPAYHRPGASGEASAGNGTPRTTATATTTTASPLREGFGGQDGGELWPLQSEGAAALVTKECQRLAAQGARPEAPKRKWAKDGGDAPSPSKRPWARQENQEAKGESGMGCDSGASNSSSSSSNTTSSSGEASARLREEVQPSAPERLALDYIVPCMRYYGICVKDNFLGAVLGGRVLAEVEALKWGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGNYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAARDKYQLASGQKGVQVPVSQPTTPT

Gene Information

Entrez Gene ID
112406
Gene Name
egl-9 family hypoxia-inducible factor 2
Gene Symbol
Egln2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:Ensembl C cytosol
GO:0005634 ISS:UniProtKB C nucleus
GO:0031418 IEA:InterPro F L-ascorbic acid binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0016706 ISS:UniProtKB F oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0019826 ISS:UniProtKB F oxygen sensor activity
GO:0031545 IEA:Ensembl F peptidyl-proline 4-dioxygenase activity
GO:0045454 ISS:UniProtKB P cell redox homeostasis
GO:0018401 IEA:Ensembl P peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0045732 IEA:Ensembl P positive regulation of protein catabolic process
GO:0043523 IEA:Ensembl P regulation of neuron apoptotic process
GO:0001666 ISS:UniProtKB P response to hypoxia

Domain Information

InterPro Annotations

Accession Description
IPR005123 Oxoglutarate/iron-dependent dioxygenase
IPR006620 Prolyl 4-hydroxylase, alpha subunit

UniProt Annotations

Entry Information

Gene Name
egl-9 family hypoxia-inducible factor 2
Protein Entry
EGLN2_MOUSE
UniProt ID
Q80X29
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP000357 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
21450783 RefSeq NP_444438 419 egl nine homolog 2

Identical Sequences to LMP000357 proteins

Reference Database Accession Length Protein Name
GI:21450783 DBBJ BAE31050.1 419 unnamed protein product [Mus musculus]
GI:21450783 GenBank AAH23299.2 419 EGL nine homolog 2 (C. elegans) [Mus musculus]
GI:21450783 GenBank AAH86764.1 419 EGL nine homolog 2 (C. elegans) [Mus musculus]
GI:21450783 GenBank EDL24202.1 419 EGL nine homolog 2 (C. elegans), isoform CRA_a [Mus musculus]
GI:21450783 GenBank EDL24203.1 419 EGL nine homolog 2 (C. elegans), isoform CRA_a [Mus musculus]
GI:21450783 SwissProt Q91YE2.2 419 RecName: Full=Egl nine homolog 2; AltName: Full=Falkor; AltName: Full=Hypoxia-inducible factor prolyl hydroxylase 1; Short=HIF-PH1; Short=HIF-prolyl hydroxylase 1; Short=HPH-1; AltName: Full=Prolyl hydroxylase domain-containing protein 1; Short=PHD1 [Mus musculus]

Related Sequences to LMP000357 proteins

Reference Database Accession Length Protein Name
GI:21450783 DBBJ BAC35835.1 419 unnamed protein product [Mus musculus]
GI:21450783 DBBJ BAE34897.1 419 unnamed protein product [Mus musculus]
GI:21450783 DBBJ BAE30912.1 419 unnamed protein product [Mus musculus]
GI:21450783 EMBL CAC42516.1 419 EGLN2 protein [Mus musculus]
GI:21450783 GenBank AAK37525.1 419 cell growth regulator Falkor [Mus musculus]
GI:21450783 RefSeq XP_005371634.1 416 PREDICTED: egl nine homolog 2 isoform X2 [Microtus ochrogaster]