LIPID MAPS

LMPD ID

LMP000185

Gene ID

13110

Species

Mus musculus (Mouse)

Gene Name

cytochrome P450, family 2, subfamily j, polypeptide 6

Gene Symbol

Cyp2j6

Synonyms

-

Alternate Names

cytochrome P450 2J6; CYPIIJ6; cytochrome P450, 2j6; arachidonic acid epoxygenase

Chromosome

4

Map Location

4 C5|4 44.62 cM

EC Number

1.14.14.1

cytochrome P450 2J6
Refseq ID	NP_034138
Protein GI	160948618
UniProt ID	O54750
mRNA ID	NM_010008
Length	501
RefSeq Status	VALIDATED
MLAATGSLLATIWAALHPRTLLVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQPHLSIQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDDHRKDWNPDEPRDFIDAFLKEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINEKLSPKFRNGLTLSPVSHRICAVPRQ

Entrez Gene ID

13110

Gene Name

cytochrome P450, family 2, subfamily j, polypeptide 6

Gene Symbol

Cyp2j6

Species

Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005783	IDA:MGI	C	endoplasmic reticulum
GO:0016020	IEA:UniProtKB-KW	C	membrane
GO:0003958	IEA:Ensembl	F	NADPH-hemoprotein reductase activity
GO:0008392	IMP:MGI	F	arachidonic acid epoxygenase activity
GO:0070330	IEA:UniProtKB-EC	F	aromatase activity
GO:0020037	IEA:InterPro	F	heme binding
GO:0005506	IEA:InterPro	F	iron ion binding
GO:0019369	IEA:Ensembl	P	arachidonic acid metabolic process
GO:0007565	IEA:Ensembl	P	female pregnancy
GO:0014070	IEA:Ensembl	P	response to organic cyclic compound
GO:0001523	IEA:Ensembl	P	retinoid metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
mmu04750	Inflammatory mediator regulation of TRP channels
mmu00591	Linoleic acid metabolism
mmu04913	Ovarian steroidogenesis
mmu04726	Serotonergic synapse

InterPro Annotations

Accession	Description
IPR001128	Cytochrome P450
IPR002401	Cytochrome P450, E-class, group I
IPR008071	Cytochrome P450, E-class, group I, CYP2J-like
IPR017972	Cytochrome P450, conserved site

Entry Information

Gene Name

cytochrome P450, family 2, subfamily j, polypeptide 6

Protein Entry

CP2J6_MOUSE

UniProt ID

O54750

Species

Mouse

Comments

Comment Type	Description
Catalytic Activity	RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.
Cofactor	Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Similarity	Belongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular Location	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Unique RefSeq proteins for LMP000185 (as displayed in Record Overview)

Protein GI	Database	Accession	Length	Protein Name
160948618	RefSeq	NP_034138	501	cytochrome P450 2J6

Identical Sequences to LMP000185 proteins

Reference	Database	Accession	Length	Protein Name
GI:160948618	DBBJ	BAC32356.1	501	unnamed protein product [Mus musculus]
GI:160948618	DBBJ	BAE38325.1	501	unnamed protein product [Mus musculus]
GI:160948618	GenBank	AAH50832.1	501	Cytochrome P450, family 2, subfamily j, polypeptide 6 [Mus musculus]
GI:160948618	GenBank	EDL30913.1	501	cytochrome P450, family 2, subfamily j, polypeptide 6 [Mus musculus]
GI:160948618	SwissProt	O54750.2	501	RecName: Full=Cytochrome P450 2J6; AltName: Full=Arachidonic acid epoxygenase; AltName: Full=CYPIIJ6 [Mus musculus]

Related Sequences to LMP000185 proteins

Reference	Database	Accession	Length	Protein Name
GI:160948618	DBBJ	BAC28391.1	501	unnamed protein product [Mus musculus]
GI:160948618	GenBank	AAB87636.1	501	cytochrome P450 monooxygenase [Mus musculus]
GI:160948618	GenBank	AAF21133.1	501	CYP2J4 [Rattus norvegicus]
GI:160948618	GenBank	AAH91149.1	501	Cytochrome P450, family 2, subfamily J, polypeptide 4 [Rattus norvegicus]
GI:160948618	GenBank	EDL97781.1	501	rCG53393 [Rattus norvegicus]
GI:160948618	RefSeq	NP_075414.2	501	cytochrome P450, family 2, subfamily j, polypeptide 4 [Rattus norvegicus]