Gene/Proteome Database (LMPD)

LMPD ID
LMP000181
Gene ID
20181
Species
Mus musculus (Mouse)
Gene Name
retinoid X receptor alpha
Gene Symbol
Rxra
Synonyms
9530071D11Rik; Nr2b1; RXRalpha1
Chromosome
2
Map Location
2 A3|2 19.38 cM

Proteins

retinoic acid receptor RXR-alpha isoform 1
Refseq ID NP_035435
Protein GI 6755384
UniProt ID Q3UMU4
mRNA ID NM_011305
Length 467
RefSeq Status VALIDATED
MDTKHFLPLDFSTQVNSSSLNSPTGRGSMAVPSLHPSLGPGIGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT
retinoic acid receptor RXR-alpha isoform 2
Refseq ID NP_001277411
Protein GI 594190946
UniProt ID Q6LC96
mRNA ID NM_001290482
Length 439
RefSeq Status VALIDATED
MAVPSLHPSLGPGIGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT
retinoic acid receptor RXR-alpha isoform 2
Refseq ID NP_001277410
Protein GI 594191033
UniProt ID Q6LC96
mRNA ID NM_001290481
Length 439
RefSeq Status VALIDATED
Protein sequence is identical to GI:594190946 (mRNA isoform)

Gene Information

Entrez Gene ID
20181
Gene Name
retinoid X receptor alpha
Gene Symbol
Rxra
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0000790 IEA:Ensembl C nuclear chromatin
GO:0005634 IDA:MGI C nucleus
GO:0004886 IDA:MGI F 9-cis retinoic acid receptor activity
GO:0003677 IDA:MGI F DNA binding
GO:0000977 IEA:Ensembl F RNA polymerase II regulatory region sequence-specific DNA binding
GO:0031490 IDA:MGI F chromatin DNA binding
GO:0004879 IDA:MGI F ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0044323 IEA:Ensembl F retinoic acid-responsive element binding
GO:0043565 IGI:MGI F sequence-specific DNA binding
GO:0003700 IGI:MGI F sequence-specific DNA binding transcription factor activity
GO:0003707 IEA:InterPro F steroid hormone receptor activity
GO:0070644 IEA:Ensembl F vitamin D response element binding
GO:0008270 IEA:InterPro F zinc ion binding
GO:0043010 IGI:MGI P camera-type eye development
GO:0060038 IMP:MGI P cardiac muscle cell proliferation
GO:0007566 IGI:MGI P embryo implantation
GO:0007507 IMP:MGI P heart development
GO:0001701 IGI:MGI P in utero embryonic development
GO:0001893 IGI:MGI P maternal placenta development
GO:0019048 IEA:Ensembl P modulation by virus of host morphology or physiology
GO:0000122 IGI:MGI P negative regulation of transcription from RNA polymerase II promoter
GO:0035357 IEA:Ensembl P peroxisome proliferator activated receptor signaling pathway
GO:0001890 IMP:MGI P placenta development
GO:0045944 IDA:MGI P positive regulation of transcription from RNA polymerase II promoter
GO:1901522 IDA:MGI P positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GO:0045893 IGI:MGI P positive regulation of transcription, DNA-templated
GO:0045994 IGI:MGI P positive regulation of translational initiation by iron
GO:0051289 IEA:Ensembl P protein homotetramerization
GO:0060687 IMP:MGI P regulation of branching involved in prostate gland morphogenesis
GO:0006357 IGI:MGI P regulation of transcription from RNA polymerase II promoter
GO:0006355 IDA:MGI P regulation of transcription, DNA-templated
GO:0032526 IEA:Ensembl P response to retinoic acid
GO:0048384 IDA:MGI P retinoic acid receptor signaling pathway
GO:0060528 IMP:MGI P secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0055012 IMP:MGI P ventricular cardiac muscle cell differentiation
GO:0055010 IMP:MGI P ventricular cardiac muscle tissue morphogenesis

Domain Information

InterPro Annotations

Accession Description
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR021780 Nuclear/hormone receptor activator site AF-1
IPR000003 Retinoid X receptor/HNF4
IPR001723 Steroid hormone receptor
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
retinoid X receptor alpha
Protein Entry
A2AJP1_MOUSE
UniProt ID
Q6LC96
Species
Mouse

Comments

Comment Type Description
Similarity Belongs to the nuclear hormone receptor family.
Similarity Contains nuclear receptor DNA-binding domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP000181 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6755384 RefSeq NP_035435 467 retinoic acid receptor RXR-alpha isoform 1
594190946 RefSeq NP_001277411 439 retinoic acid receptor RXR-alpha isoform 2

Identical Sequences to LMP000181 proteins

Reference Database Accession Length Protein Name
GI:594190946 GenBank AAB36777.1 439 RXR alpha 2 [Mus musculus]
GI:594190946 GenBank AAB36778.1 439 RXR alpha 3 [Mus musculus]
GI:6755384 GenBank AAI38803.1 467 Retinoid X receptor alpha [Mus musculus]
GI:6755384 GenBank AAI38801.1 467 Retinoid X receptor alpha [Mus musculus]
GI:6755384 GenBank ACP80942.1 467 Sequence 4 from patent US 7501487
GI:6755384 GenBank ADS25914.1 467 Sequence 54 from patent US 7776587
GI:6755384 GenBank ADS61812.1 467 Sequence 54 from patent US 7807417
GI:6755384 GenBank AFN93447.1 467 Sequence 54 from patent US 8202718
GI:594190946 RefSeq XP_006497868.1 439 PREDICTED: retinoic acid receptor RXR-alpha isoform X5 [Mus musculus]
GI:594190946 RefSeq NP_001277410.1 439 retinoic acid receptor RXR-alpha isoform 2 [Mus musculus]

Related Sequences to LMP000181 proteins

Reference Database Accession Length Protein Name
GI:6755384 DBBJ BAE26004.1 467 unnamed protein product [Mus musculus]
GI:6755384 EMBL CAL25727.1 467 retinoid X receptor alpha [Rattus norvegicus]
GI:6755384 EMBL CAL25728.1 467 retinoid X receptor alpha [Rattus norvegicus]
GI:6755384 EMBL CAL36079.1 467 retinoid X receptor alpha [Rattus norvegicus]
GI:594190946 GenBank AAA40080.1 467 retinoid X receptor alpha [Mus musculus]
GI:594190946 GenBank ABJ25768.1 467 Sequence 63 from patent US 7091038
GI:6755384 GenBank EDL93429.1 467 retinoid X receptor alpha, isoform CRA_a [Rattus norvegicus]
GI:594190946 GenBank AAI38803.1 467 Retinoid X receptor alpha [Mus musculus]
GI:594190946 GenBank AAI38801.1 467 Retinoid X receptor alpha [Mus musculus]
GI:594190946 GenBank ADS25914.1 467 Sequence 54 from patent US 7776587
GI:6755384 RefSeq NP_036937.2 467 retinoic acid receptor RXR-alpha [Rattus norvegicus]
GI:594190946 SwissProt P28700.1 467 RecName: Full=Retinoic acid receptor RXR-alpha; AltName: Full=Nuclear receptor subfamily 2 group B member 1; AltName: Full=Retinoid X receptor alpha [Mus musculus]