Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Vitamin digestion and absorption (mmu04977)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
2310046K
01Rik
KLA  Compactin  Compactin+KLA
 NM_027172 RIKEN cDNA 2310046K01 gene (2310046K01Rik), mRNA [NM_027172] KLA0.970 1.000 0.970 1.160 1.160 1.150 0.890
Compactin0.990 1.020 0.970 1.000 0.970 1.070 1.500
KLA/Compactin0.980 1.000 0.920 1.190 1.330 1.330 0.940
2310046K
01Rik
KLA  Compactin  Compactin+KLA
 NM_027172 RIKEN cDNA 2310046K01 gene (2310046K01Rik), mRNA [NM_027172] KLA1.070 1.000 0.980 1.070 1.020 1.010 1.000
Compactin1.030 1.010 0.980 1.060 1.020 0.960 1.030
KLA/Compactin0.990 0.970 0.980 0.980 1.020 1.100 0.950
Abcc1
KLA  Compactin  Compactin+KLA
 NM_008576 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), mRNA [NM_008576] KLA1.080 0.990 1.360 0.960 1.460 2.110 2.750
Compactin1.040 1.030 0.990 0.960 0.940 1.040 1.270
KLA/Compactin1.050 1.110 1.220 1.150 1.490 2.820 3.380
Abcc1
KLA  Compactin  Compactin+KLA
 NM_008576 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), mRNA [NM_008576] KLA1.120 1.020 1.450 1.230 1.430 2.180 3.080
Compactin1.260 1.140 1.090 1.210 0.980 0.960 1.230
KLA/Compactin1.260 1.070 1.470 1.410 1.690 2.490 3.330
Abcc1
KLA  Compactin  Compactin+KLA
 NM_008576 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), mRNA [NM_008576] KLA1.190 1.090 1.420 1.470 1.550 1.940 2.340
Compactin1.130 1.170 1.060 1.160 0.910 1.110 1.390
KLA/Compactin1.120 1.130 1.440 1.430 1.610 2.530 2.880
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA0.950 1.000 1.000 1.070 0.990 0.960 1.180
Compactin1.000 0.990 0.970 1.020 1.000 0.920 0.990
KLA/Compactin1.060 1.000 0.960 0.950 1.020 1.000 0.970
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA0.970 1.010 0.930 0.940 0.980 1.000 1.020
Compactin0.970 1.000 1.050 0.950 0.990 0.990 1.020
KLA/Compactin0.990 1.060 1.050 1.050 0.980 1.040 1.040
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA0.970 1.010 1.070 0.970 1.020 1.490 0.990
Compactin1.020 0.980 1.280 1.080 0.990 0.910 1.000
KLA/Compactin0.960 0.990 1.010 1.020 1.000 0.970 1.020
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA0.970 1.050 0.960 1.020 1.020 0.920 0.970
Compactin1.000 0.990 1.010 1.000 1.090 1.000 0.980
KLA/Compactin0.970 1.070 0.990 1.000 0.970 1.050 0.980
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA0.980 0.960 0.930 1.030 1.070 1.050 1.010
Compactin0.940 0.970 1.040 1.050 0.900 1.040 1.020
KLA/Compactin0.990 1.020 0.990 1.010 1.050 1.020 1.010
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA0.980 1.020 0.980 0.950 1.210 1.000 1.000
Compactin0.980 0.970 1.000 1.010 0.960 0.970 1.040
KLA/Compactin0.970 1.020 1.020 1.060 1.000 0.990 1.010
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA1.000 0.920 1.040 1.000 1.070 0.950 0.970
Compactin1.000 0.980 1.030 0.990 0.990 1.050 0.980
KLA/Compactin0.930 1.040 0.990 0.950 1.080 1.080 0.980
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA1.010 1.020 0.980 0.920 1.030 1.000 1.050
Compactin0.980 0.970 1.020 1.050 0.910 0.950 1.050
KLA/Compactin1.010 0.960 0.990 1.010 1.030 0.980 0.950
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA1.020 1.010 0.960 0.990 0.970 0.900 1.010
Compactin1.060 1.010 1.110 1.010 1.020 1.040 1.010
KLA/Compactin0.960 1.000 0.950 1.030 0.980 0.910 1.020
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA1.030 0.980 1.020 0.970 0.990 1.000 1.000
Compactin0.950 0.990 0.950 1.050 1.030 1.040 1.020
KLA/Compactin1.000 1.010 0.990 0.980 0.980 1.010 0.970
Apoa1
KLA  Compactin  Compactin+KLA
 NM_009692 apolipoprotein A-I (Apoa1), mRNA [NM_009692] KLA1.040 1.010 1.040 0.950 1.010 1.010 0.980
Compactin1.020 1.050 0.980 0.980 0.960 1.030 1.090
KLA/Compactin1.000 0.980 0.950 1.000 1.050 0.990 0.990
Apoa4
KLA  Compactin  Compactin+KLA
 NM_007468 apolipoprotein A-IV (Apoa4), mRNA [NM_007468] KLA0.970 0.980 0.960 1.040 1.020 1.070 1.000
Compactin1.040 1.000 0.960 0.930 1.020 0.990 1.060
KLA/Compactin1.000 0.950 0.990 0.960 1.040 1.140 1.090
Apob
KLA  Compactin  Compactin+KLA
 NM_009693 apolipoprotein B (Apob), mRNA [NM_009693] KLA0.960 0.950 0.950 0.920 1.000 1.020 0.970
Compactin0.930 0.980 1.020 0.980 1.030 1.000 0.930
KLA/Compactin0.950 0.950 1.030 0.950 1.090 0.840 1.010
Apob
KLA  Compactin  Compactin+KLA
 NM_009693 apolipoprotein B (Apob), mRNA [NM_009693] KLA0.990 0.970 1.070 1.010 1.010 1.120 1.020
Compactin0.990 0.980 0.980 0.990 0.970 1.080 1.080
KLA/Compactin1.020 0.970 1.050 0.980 1.040 1.000 1.000
Btd
KLA  Compactin  Compactin+KLA
 NM_025295 biotinidase (Btd), mRNA [NM_025295] KLA1.090 1.020 1.050 0.650 0.740 0.840 0.710
Compactin1.050 1.130 1.180 1.150 1.140 1.110 1.020
KLA/Compactin1.060 1.080 1.100 0.820 1.000 0.930 0.680
Cubn
KLA  Compactin  Compactin+KLA
 NM_001081084 cubilin (intrinsic factor-cobalamin receptor) (Cubn), mRNA [NM_001081084] KLA1.020 1.150 1.080 0.950 0.840 0.990 0.960
Compactin1.040 1.010 1.040 0.970 1.160 1.090 1.230
KLA/Compactin1.090 0.950 0.990 0.970 0.940 0.920 0.920
Cubn
KLA  Compactin  Compactin+KLA
 NM_001081084 cubilin (intrinsic factor-cobalamin receptor) (Cubn), mRNA [NM_001081084] KLA1.070 1.070 1.030 0.990 0.910 0.960 0.950
Compactin1.090 1.030 1.080 0.990 1.140 1.060 1.120
KLA/Compactin1.050 1.050 1.010 0.950 0.850 1.030 0.860
Dgat2l4
KLA  Compactin  Compactin+KLA
 NM_177746 diacylglycerol O-acyltransferase 2-like 4 (Dgat2l4), mRNA [NM_177746] KLA1.050 1.000 0.990 0.950 0.980 1.010 0.960
Compactin0.980 1.020 1.020 0.960 0.900 1.000 1.060
KLA/Compactin1.010 0.940 0.980 1.060 0.970 0.900 0.960
Folh1
KLA  Compactin  Compactin+KLA
 31980799 folate hydrolase KLA0.970 1.050 0.940 1.020 1.000 0.990 1.010
Compactin0.950 1.050 1.060 0.970 1.040 0.970 1.060
KLA/Compactin1.060 0.970 0.990 0.910 0.990 1.000 0.950
Folh1
KLA  Compactin  Compactin+KLA
 NM_016770 folate hydrolase (Folh1), mRNA [NM_016770] KLA1.020 1.000 0.970 1.000 1.030 0.960 1.050
Compactin0.990 1.050 1.020 0.980 1.060 1.000 0.940
KLA/Compactin1.030 0.980 1.030 0.950 1.020 0.970 1.030
Gif
KLA  Compactin  Compactin+KLA
 NM_008118 gastric intrinsic factor (Gif), mRNA [NM_008118] KLA1.000 0.970 0.990 0.990 1.050 0.920 1.030
Compactin0.980 0.990 0.950 0.910 1.030 0.980 0.980
KLA/Compactin1.000 1.000 0.980 1.000 0.970 1.020 1.020
Lmbrd1
KLA  Compactin  Compactin+KLA
 NM_026719 LMBR1 domain containing 1 (Lmbrd1), mRNA [NM_026719] KLA0.900 1.060 0.940 0.970 0.910 0.870 0.810
Compactin1.030 1.040 1.010 0.930 0.970 1.010 0.990
KLA/Compactin0.970 1.000 0.990 0.950 0.890 0.830 0.720
Lmbrd1
KLA  Compactin  Compactin+KLA
 NM_026719 LMBR1 domain containing 1 (Lmbrd1), mRNA [NM_026719] KLA0.920 0.930 0.940 0.960 0.930 0.820 0.750
Compactin1.010 1.010 0.970 0.870 0.970 1.000 1.000
KLA/Compactin0.890 0.930 0.970 1.000 0.870 0.880 0.750
Lmbrd1
KLA  Compactin  Compactin+KLA
 NM_026719 LMBR1 domain containing 1 (Lmbrd1), mRNA [NM_026719] KLA1.180 1.240 1.560 1.450 1.920 2.460 2.410
Compactin1.160 1.180 1.090 1.060 1.060 0.860 1.140
KLA/Compactin1.190 1.220 1.350 1.560 1.800 2.070 1.960
Lrat
KLA  Compactin  Compactin+KLA
 NM_023624 lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) (Lrat), mRNA [NM_023624] KLA0.980 1.000 0.990 1.000 0.990 0.960 0.940
Compactin1.020 0.960 0.970 0.970 1.010 1.040 1.060
KLA/Compactin0.980 0.960 1.000 0.970 0.970 1.060 0.980
Lrat
KLA  Compactin  Compactin+KLA
 NM_023624 lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) (Lrat), mRNA [NM_023624] KLA1.040 0.980 0.980 0.990 0.970 1.040 0.980
Compactin0.990 1.030 1.010 1.020 0.960 0.960 1.030
KLA/Compactin1.000 0.950 1.130 1.070 0.980 0.900 0.980
Mmachc
KLA  Compactin  Compactin+KLA
 NM_025962 methylmalonic aciduria cblC type, with homocystinuria (Mmachc), mRNA [NM_025962] KLA1.050 1.010 1.100 1.070 0.740 0.730 0.610
Compactin1.190 1.030 1.120 1.230 1.010 1.000 1.100
KLA/Compactin1.220 1.010 1.070 1.070 0.760 0.690 0.480
Plb1
KLA  Compactin  Compactin+KLA
 124487226 phospholipase B1 KLA0.990 1.000 1.020 1.000 0.970 1.070 1.020
Compactin0.950 0.990 1.050 1.000 0.950 1.030 1.070
KLA/Compactin1.030 0.980 0.950 0.940 0.940 0.910 0.970
Plb1
KLA  Compactin  Compactin+KLA
 AK015993 adult male testis cDNA, RIKEN full-length enriched library, clone:4930539A06 product:weakly similar to PHOSPHOLIPASE B [Rattus norvegicus], full insert sequence. [AK015993] KLA0.960 0.940 1.030 1.030 0.990 0.930 0.990
Compactin1.060 1.000 0.950 0.950 1.080 1.010 1.000
KLA/Compactin1.000 1.050 1.090 1.020 1.000 0.980 1.030
Plb1
KLA  Compactin  Compactin+KLA
 NM_001081407 phospholipase B1 (Plb1), mRNA [NM_001081407] KLA0.970 0.960 0.930 1.050 0.960 1.000 1.030
Compactin0.960 0.950 1.010 0.960 0.960 1.030 0.890
KLA/Compactin0.860 0.990 1.010 1.000 0.940 1.020 1.020
Plb1
KLA  Compactin  Compactin+KLA
 NM_001081407 phospholipase B1 (Plb1), mRNA [NM_001081407] KLA1.070 1.010 1.080 1.030 0.960 1.020 1.030
Compactin1.000 1.030 1.030 0.990 1.020 0.950 0.980
KLA/Compactin1.020 1.010 1.020 1.020 1.030 1.060 0.930
Pnlip
KLA  Compactin  Compactin+KLA
 AK007357 10 day old male pancreas cDNA, RIKEN full-length enriched library, clone:1810007A24 product:PANCREATIC TRIGLYCERIDE LIPASE (FRAGMENT) homolog [Rattus norvegicus], full insert sequence. [AK007357] KLA0.980 0.930 1.010 1.050 0.950 1.040 1.100
Compactin1.040 0.960 1.050 1.000 1.030 1.010 1.020
KLA/Compactin1.040 1.040 1.010 0.980 1.080 1.020 1.020
Pnlip
KLA  Compactin  Compactin+KLA
 NM_026925 pancreatic lipase (Pnlip), mRNA [NM_026925] KLA1.030 1.020 1.050 1.040 1.060 1.000 0.970
Compactin1.050 1.010 1.010 1.010 1.040 0.970 1.000
KLA/Compactin1.000 1.040 0.980 0.970 0.960 1.040 1.060
Rbp2
KLA  Compactin  Compactin+KLA
 NM_009034 retinol binding protein 2, cellular (Rbp2), mRNA [NM_009034] KLA0.990 0.960 1.040 0.970 1.010 0.950 0.940
Compactin1.000 0.980 1.020 0.980 1.090 1.010 0.970
KLA/Compactin0.970 0.970 0.960 0.990 1.010 1.060 0.930
Rbp2
KLA  Compactin  Compactin+KLA
 NM_009034 retinol binding protein 2, cellular (Rbp2), mRNA [NM_009034] KLA1.020 0.990 0.990 0.980 0.970 0.970 0.970
Compactin1.000 1.030 1.030 1.000 1.020 1.030 0.980
KLA/Compactin0.960 1.040 1.030 1.000 1.030 1.000 1.040
Scarb1
KLA  Compactin  Compactin+KLA
 NM_016741 scavenger receptor class B, member 1 (Scarb1), mRNA [NM_016741] KLA0.940 0.950 0.910 0.640 0.620 0.870 1.010
Compactin0.980 0.990 0.960 1.070 1.040 1.340 1.380
KLA/Compactin1.040 0.850 0.790 0.610 0.820 0.950 1.320
Slc19a1
KLA  Compactin  Compactin+KLA
 NM_031196 solute carrier family 19 (sodium/hydrogen exchanger), member 1 (Slc19a1), mRNA [NM_031196] KLA0.920 0.970 1.030 0.750 0.680 0.720 0.780
Compactin0.940 0.880 0.920 0.920 0.810 0.920 0.990
KLA/Compactin0.960 0.930 0.880 0.700 0.660 0.630 0.710
Slc19a1
KLA  Compactin  Compactin+KLA
 NM_031196 solute carrier family 19 (sodium/hydrogen exchanger), member 1 (Slc19a1), mRNA [NM_031196] KLA1.140 1.060 1.180 1.010 0.970 0.990 0.880
Compactin1.120 1.180 1.150 1.160 0.960 1.000 0.910
KLA/Compactin1.180 1.080 1.250 1.030 0.900 0.800 1.010
Slc19a2
KLA  Compactin  Compactin+KLA
 NM_054087 solute carrier family 19 (thiamine transporter), member 2 (Slc19a2), mRNA [NM_054087] KLA0.890 0.950 0.770 0.330 0.460 0.590 0.820
Compactin0.830 0.830 0.920 0.870 0.950 0.930 0.850
KLA/Compactin0.900 0.970 0.820 0.380 0.470 0.730 0.830
Slc19a3
KLA  Compactin  Compactin+KLA
 AK098112 cDNA fis, clone TRACH2007674,weakly similar to FOLATE-LIKE TRANSPORTER [AK098112] KLA1.020 0.990 1.030 0.950 0.980 1.040 1.030
Compactin0.880 1.010 0.950 0.930 0.920 1.030 1.060
KLA/Compactin1.020 0.910 0.970 1.050 0.960 0.870 0.970
Slc19a3
KLA  Compactin  Compactin+KLA
 NM_030556 solute carrier family 19 (sodium/hydrogen exchanger), member 3 (Slc19a3), mRNA [NM_030556] KLA0.950 0.990 1.060 1.000 0.980 0.900 1.020
Compactin1.050 1.010 0.960 0.950 1.030 1.090 0.940
KLA/Compactin1.030 1.000 1.090 0.940 1.010 0.950 1.010
Slc23a1
KLA  Compactin  Compactin+KLA
 NM_011397 solute carrier family 23 (nucleobase transporters), member 1 (Slc23a1), mRNA [NM_011397] KLA1.010 1.060 1.010 1.020 0.960 0.990 0.920
Compactin1.020 0.970 0.980 1.020 1.040 0.970 1.010
KLA/Compactin0.930 0.980 1.070 0.960 1.000 1.030 0.920
Slc23a1
KLA  Compactin  Compactin+KLA
 NM_011397 solute carrier family 23 (nucleobase transporters), member 1 (Slc23a1), mRNA [NM_011397] KLA1.080 0.980 0.980 0.980 0.990 1.050 0.970
Compactin0.950 0.970 1.030 0.950 0.970 1.090 1.010
KLA/Compactin1.020 0.980 1.030 1.020 1.040 1.030 1.040
Slc46a1
KLA  Compactin  Compactin+KLA
 NM_026740 solute carrier family 46, member 1 (Slc46a1), mRNA [NM_026740] KLA1.040 0.990 0.920 0.860 0.660 0.960 1.100
Compactin1.020 1.120 1.070 1.070 1.000 1.030 1.120
KLA/Compactin1.070 1.030 0.920 0.860 0.770 0.870 0.930
Slc5a6
KLA  Compactin  Compactin+KLA
 NM_177870 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 (Slc5a6), mRNA [NM_177870] KLA1.050 1.010 0.940 0.640 0.650 0.660 0.720
Compactin1.100 1.090 1.060 1.050 0.940 0.930 0.870
KLA/Compactin1.110 0.970 1.000 0.640 0.620 0.570 0.670
Tcn2
KLA  Compactin  Compactin+KLA
 NM_015749 transcobalamin 2 (Tcn2), mRNA [NM_015749] KLA1.000 0.920 0.960 0.920 0.840 1.040 2.270
Compactin0.920 0.900 1.040 1.100 0.950 0.960 1.120
KLA/Compactin1.040 0.960 0.970 0.890 0.870 0.970 1.760