Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Mismatch repair (mmu03430)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
AK038264
KLA  Compactin  Compactin+KLA
 AK038264 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130091A22 product:unclassifiable, full insert sequence. [AK038264] KLA1.120 0.910 0.900 0.940 1.080 1.220 1.190
Compactin1.030 1.030 0.960 1.050 0.970 0.920 1.190
KLA/Compactin1.150 0.850 0.890 0.990 1.030 1.000 1.110
Exo1
KLA  Compactin  Compactin+KLA
 NM_012012 exonuclease 1 (Exo1), mRNA [NM_012012] KLA0.800 0.920 0.530 0.310 0.310 0.180 0.120
Compactin0.800 0.890 0.860 0.730 0.930 0.980 0.530
KLA/Compactin0.870 0.930 0.570 0.340 0.180 0.120 0.120
Lig1
KLA  Compactin  Compactin+KLA
 133892806 ligase I, DNA, ATP-dependent KLA1.030 1.040 0.960 0.720 0.410 0.390 0.360
Compactin0.950 0.970 0.930 1.130 0.930 0.960 0.660
KLA/Compactin1.030 1.120 0.950 0.810 0.380 0.330 0.360
Lig1
KLA  Compactin  Compactin+KLA
 NM_010715 ligase I, DNA, ATP-dependent (Lig1), transcript variant 2, mRNA [NM_010715] KLA1.070 0.960 0.830 0.730 0.430 0.400 0.440
Compactin0.960 0.990 1.040 0.990 0.800 0.980 0.580
KLA/Compactin0.950 1.000 0.890 0.780 0.350 0.380 0.490
Mlh1
KLA  Compactin  Compactin+KLA
 NM_026810 mutL homolog 1 (E. coli) (Mlh1), mRNA [NM_026810] KLA1.050 0.960 1.000 0.770 0.630 0.680 0.560
Compactin1.080 1.080 1.160 1.220 1.060 1.000 0.800
KLA/Compactin1.010 1.010 1.000 0.930 0.650 0.520 0.470
Mlh3
KLA  Compactin  Compactin+KLA
 NM_175337 mutL homolog 3 (E coli) (Mlh3), mRNA [NM_175337] KLA0.940 0.880 0.890 0.820 0.900 0.900 0.810
Compactin1.020 1.100 1.000 1.010 0.920 0.920 1.050
KLA/Compactin0.980 0.890 0.890 0.890 0.920 0.900 0.930
Mlh3
KLA  Compactin  Compactin+KLA
 NM_175337 mutL homolog 3 (E coli) (Mlh3), mRNA [NM_175337] KLA1.050 0.970 0.880 1.030 0.950 1.130 1.170
Compactin1.040 1.040 1.050 1.140 1.040 1.030 1.060
KLA/Compactin1.170 1.020 0.810 0.980 0.900 1.180 0.980
Msh2
KLA  Compactin  Compactin+KLA
 AK051960 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230024H20 product:mutS homolog 2 (E. coli), full insert sequence. [AK051960] KLA0.990 0.990 0.960 0.980 1.020 0.940 0.980
Compactin1.030 1.020 1.030 1.020 1.680 1.030 1.000
KLA/Compactin0.910 0.990 1.060 1.010 0.990 0.990 0.990
Msh2
KLA  Compactin  Compactin+KLA
 AK078775 15 days embryo male testis cDNA, RIKEN full-length enriched library, clone:8030473G08 product:mutS homolog 2 (E. coli), full insert sequence. [AK078775] KLA0.730 0.690 0.700 0.670 0.780 0.860 0.810
Compactin1.010 1.080 0.990 1.090 1.070 1.050 1.090
KLA/Compactin0.800 0.650 0.720 0.780 0.780 0.790 0.830
Msh2
KLA  Compactin  Compactin+KLA
 NM_008628 mutS homolog 2 (E. coli) (Msh2), mRNA [NM_008628] KLA0.890 0.980 0.830 0.390 0.250 0.310 0.220
Compactin0.920 1.000 0.930 0.910 0.880 0.950 0.770
KLA/Compactin0.960 0.890 0.780 0.420 0.270 0.270 0.200
Msh2
KLA  Compactin  Compactin+KLA
 NM_008628 mutS homolog 2 (E. coli) (Msh2), mRNA [NM_008628] KLA1.010 1.090 1.000 0.460 0.250 0.360 0.260
Compactin1.110 1.090 1.260 1.200 1.000 1.010 0.820
KLA/Compactin1.160 1.070 0.960 0.470 0.270 0.300 0.210
Msh3
KLA  Compactin  Compactin+KLA
 NM_010829 mutS homolog 3 (E. coli) (Msh3), mRNA [NM_010829] KLA0.920 0.980 0.800 0.690 0.970 1.150 1.620
Compactin0.960 0.930 0.920 0.980 0.890 0.830 1.160
KLA/Compactin0.960 0.940 0.650 0.580 0.750 0.940 1.070
Msh3
KLA  Compactin  Compactin+KLA
 NM_010829 mutS homolog 3 (E. coli) (Msh3), mRNA [NM_010829] KLA0.970 1.000 0.910 0.860 0.920 1.000 1.250
Compactin0.970 1.080 0.900 0.910 0.890 0.880 1.030
KLA/Compactin1.050 0.990 0.920 0.800 0.970 0.920 1.070
Msh3
KLA  Compactin  Compactin+KLA
 NM_010829 mutS homolog 3 (E. coli) (Msh3), mRNA [NM_010829] KLA0.980 0.900 0.840 0.780 1.000 1.040 1.210
Compactin1.020 1.020 0.920 0.980 0.910 0.840 1.040
KLA/Compactin0.960 0.960 0.840 0.680 0.860 0.950 0.970
Msh6
KLA  Compactin  Compactin+KLA
 NM_010830 mutS homolog 6 (E. coli) (Msh6), mRNA [NM_010830] KLA0.950 0.970 0.800 0.280 0.290 0.370 0.920
Compactin1.010 0.930 0.990 1.040 0.890 0.870 0.620
KLA/Compactin1.020 0.960 0.810 0.290 0.290 0.480 0.750
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA0.820 0.980 0.850 0.740 0.720 0.470 0.370
Compactin0.860 1.100 1.050 0.890 1.010 1.280 0.920
KLA/Compactin0.930 1.100 0.930 0.710 0.450 0.370 0.390
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA0.890 0.940 0.910 0.820 0.530 0.510 0.430
Compactin0.970 0.880 1.020 1.130 1.100 1.210 0.950
KLA/Compactin0.970 0.920 0.800 0.740 0.610 0.520 0.320
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA0.970 0.870 0.890 0.740 0.570 0.420 0.340
Compactin0.950 1.070 0.840 0.750 1.130 1.270 1.040
KLA/Compactin0.910 0.920 0.840 0.640 0.530 0.520 0.290
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA0.980 1.000 0.910 0.860 0.520 0.470 0.420
Compactin0.990 1.100 1.110 1.110 1.140 1.050 0.790
KLA/Compactin1.020 0.960 0.980 0.680 0.530 0.520 0.300
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA1.000 0.900 0.880 0.740 0.600 0.520 0.360
Compactin0.980 1.000 1.020 1.070 0.980 1.110 1.070
KLA/Compactin0.810 0.980 0.980 0.630 0.600 0.450 0.290
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA1.000 1.060 0.980 0.830 0.520 0.470 0.400
Compactin1.020 1.050 1.060 1.100 1.150 1.440 0.850
KLA/Compactin0.990 0.990 0.880 0.640 0.590 0.480 0.300
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA1.030 0.940 0.950 0.750 0.520 0.460 0.330
Compactin0.910 1.070 0.900 0.930 1.110 0.980 0.890
KLA/Compactin0.920 0.990 0.980 0.640 0.510 0.390 0.270
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA1.060 1.060 0.980 0.790 0.510 0.580 0.380
Compactin1.060 0.970 1.050 1.220 1.090 1.090 0.940
KLA/Compactin1.050 1.100 1.000 0.690 0.550 0.480 0.300
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA1.060 1.170 1.030 0.930 0.560 0.550 0.380
Compactin1.030 1.200 1.080 1.420 1.180 1.190 0.890
KLA/Compactin1.080 1.110 1.090 0.750 0.670 0.590 0.330
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA1.070 1.180 1.020 0.900 0.520 0.560 0.360
Compactin0.950 1.010 0.980 1.050 1.070 1.190 1.020
KLA/Compactin0.970 0.990 0.930 0.720 0.550 0.470 0.320
Pcna
KLA  Compactin  Compactin+KLA
 NM_011045 proliferating cell nuclear antigen (Pcna), mRNA [NM_011045] KLA1.420 1.280 1.260 0.860 0.540 0.590 0.360
Compactin1.150 1.180 1.190 1.110 1.210 1.070 0.930
KLA/Compactin1.320 0.990 1.090 0.910 0.550 0.460 0.300
Pms2
KLA  Compactin  Compactin+KLA
 121583909 postmeiotic segregation increased 2 (S. cerevisiae) KLA0.990 0.970 0.850 0.850 0.860 0.860 0.870
Compactin1.060 1.020 1.050 0.940 0.950 1.080 0.940
KLA/Compactin1.030 0.960 0.910 0.820 0.840 0.850 0.780
Pms2
KLA  Compactin  Compactin+KLA
 NM_008886 postmeiotic segregation increased 2 (S. cerevisiae) (Pms2), mRNA [NM_008886] KLA0.810 0.770 0.520 0.560 0.730 0.500 0.450
Compactin0.840 0.970 0.960 0.700 0.980 1.070 0.730
KLA/Compactin0.900 0.780 0.650 0.480 0.450 0.420 0.540
Pms2
KLA  Compactin  Compactin+KLA
 NM_008886 postmeiotic segregation increased 2 (S. cerevisiae) (Pms2), mRNA [NM_008886] KLA0.810 0.840 0.510 0.500 0.680 0.520 0.520
Compactin0.890 0.970 0.910 0.880 1.040 0.990 0.660
KLA/Compactin0.850 0.850 0.620 0.520 0.500 0.430 0.510
Pold1
KLA  Compactin  Compactin+KLA
 NM_011131 polymerase (DNA directed), delta 1, catalytic subunit (Pold1), mRNA [NM_011131] KLA0.730 0.890 0.640 0.430 0.410 0.340 0.380
Compactin0.850 1.010 0.940 0.760 0.940 1.020 0.700
KLA/Compactin0.910 1.020 0.780 0.380 0.330 0.440 0.540
Pold1
KLA  Compactin  Compactin+KLA
 NM_011131 polymerase (DNA directed), delta 1, catalytic subunit (Pold1), mRNA [NM_011131] KLA0.820 0.790 0.680 0.420 0.400 0.340 0.560
Compactin0.880 0.930 0.770 0.720 1.050 1.010 0.640
KLA/Compactin0.930 0.880 0.630 0.350 0.340 0.450 0.420
Pold1
KLA  Compactin  Compactin+KLA
 NM_011131 polymerase (DNA directed), delta 1, catalytic subunit (Pold1), mRNA [NM_011131] KLA1.000 0.950 0.830 0.460 0.350 0.440 0.500
Compactin1.020 0.900 0.970 1.020 0.930 1.000 0.760
KLA/Compactin1.010 0.970 0.720 0.460 0.420 0.470 0.500
Pold2
KLA  Compactin  Compactin+KLA
 NM_008894 polymerase (DNA directed), delta 2, regulatory subunit (Pold2), mRNA [NM_008894] KLA0.960 0.960 0.920 0.750 0.810 0.710 0.750
Compactin0.920 0.970 1.010 0.860 0.980 0.950 0.920
KLA/Compactin0.850 0.930 0.990 0.780 0.590 0.600 0.880
Pold2
KLA  Compactin  Compactin+KLA
 NM_008894 polymerase (DNA directed), delta 2, regulatory subunit (Pold2), mRNA [NM_008894] KLA1.490 1.070 1.290 1.130 0.760 0.760 0.890
Compactin1.160 1.200 1.180 1.350 1.290 0.950 0.810
KLA/Compactin1.180 1.140 1.220 1.060 0.760 0.640 0.820
Pold3
KLA  Compactin  Compactin+KLA
 NM_133692 polymerase (DNA-directed), delta 3, accessory subunit (Pold3), mRNA [NM_133692] KLA0.870 1.050 0.900 1.140 1.120 1.220 1.860
Compactin0.900 0.880 0.970 0.840 1.040 1.220 0.970
KLA/Compactin0.970 1.060 1.040 1.010 0.950 1.500 1.900
Pold3
KLA  Compactin  Compactin+KLA
 NM_133692 polymerase (DNA-directed), delta 3, accessory subunit (Pold3), mRNA [NM_133692] KLA1.120 1.010 0.930 0.820 0.680 0.680 0.690
Compactin1.240 1.090 1.070 0.900 0.930 0.940 0.800
KLA/Compactin1.000 1.350 1.000 0.900 0.660 0.790 0.750
Pold3
KLA  Compactin  Compactin+KLA
 NM_133692 polymerase (DNA-directed), delta 3, accessory subunit (Pold3), mRNA [NM_133692] KLA1.400 1.180 1.190 1.270 1.070 1.430 2.060
Compactin1.110 1.100 1.090 1.230 1.080 0.930 0.890
KLA/Compactin1.110 1.080 1.170 1.270 1.120 1.260 1.960
Pold4
KLA  Compactin  Compactin+KLA
 NM_027196 polymerase (DNA-directed), delta 4 (Pold4), mRNA [NM_027196] KLA1.110 1.170 1.190 1.270 1.260 1.360 1.600
Compactin1.270 1.060 1.110 1.200 1.170 1.120 1.370
KLA/Compactin1.100 1.050 1.160 1.340 1.480 1.520 2.040
Rfc1
KLA  Compactin  Compactin+KLA
 NM_011258 replication factor C (activator 1) 1 (Rfc1), mRNA [NM_011258] KLA0.890 0.930 0.780 0.520 0.530 0.560 0.490
Compactin1.020 1.010 1.210 1.050 1.020 0.900 0.740
KLA/Compactin0.990 0.920 0.850 0.550 0.580 0.600 0.440
Rfc2
KLA  Compactin  Compactin+KLA
 NM_020022 replication factor C (activator 1) 2 (Rfc2), mRNA [NM_020022] KLA1.010 0.910 0.890 0.610 0.400 0.450 0.630
Compactin1.100 1.070 1.090 0.990 1.140 0.820 0.590
KLA/Compactin1.110 0.980 0.850 0.740 0.490 0.470 0.550
Rfc2
KLA  Compactin  Compactin+KLA
 NM_020022 replication factor C (activator 1) 2 (Rfc2), mRNA [NM_020022] KLA1.120 0.950 0.920 0.680 0.460 0.550 0.640
Compactin1.010 1.080 1.030 1.090 1.050 1.000 0.640
KLA/Compactin0.970 0.990 1.000 0.700 0.470 0.510 0.730
Rfc3
KLA  Compactin  Compactin+KLA
 NM_027009 replication factor C (activator 1) 3 (Rfc3), mRNA [NM_027009] KLA1.120 1.060 0.990 0.890 0.650 0.680 0.780
Compactin1.170 1.110 1.030 1.190 0.970 0.870 0.700
KLA/Compactin1.120 1.090 1.060 1.020 0.740 0.650 0.710
Rfc4
KLA  Compactin  Compactin+KLA
 21703947 replication factor C (activator 1) 4 KLA0.900 0.900 0.790 0.700 0.430 0.330 0.340
Compactin0.920 1.020 1.040 0.910 0.880 0.960 0.720
KLA/Compactin0.900 1.140 0.920 0.610 0.410 0.330 0.330
Rfc4
KLA  Compactin  Compactin+KLA
 NM_145480 replication factor C (activator 1) 4 (Rfc4), mRNA [NM_145480] KLA0.940 0.930 0.880 0.720 0.360 0.370 0.420
Compactin0.950 1.020 0.840 1.060 0.860 0.880 0.760
KLA/Compactin0.900 1.020 0.930 0.600 0.440 0.350 0.330
Rfc5
KLA  Compactin  Compactin+KLA
 NM_028128 replication factor C (activator 1) 5 (Rfc5), mRNA [NM_028128] KLA0.870 0.900 0.920 0.900 0.410 0.310 0.240
Compactin1.010 0.990 1.020 1.170 0.950 0.780 0.560
KLA/Compactin1.000 0.880 0.880 0.800 0.470 0.320 0.210
Rpa1
KLA  Compactin  Compactin+KLA
 NM_026653 replication protein A1 (Rpa1), mRNA [NM_026653] KLA0.720 0.810 0.650 0.540 0.440 0.350 0.470
Compactin0.810 0.880 0.840 0.820 0.890 0.950 0.700
KLA/Compactin0.790 0.880 0.810 0.500 0.290 0.330 0.580
Rpa1
KLA  Compactin  Compactin+KLA
 NM_026653 replication protein A1 (Rpa1), mRNA [NM_026653] KLA0.900 0.830 0.770 0.560 0.340 0.450 0.480
Compactin0.840 0.970 0.900 0.870 0.940 1.090 0.860
KLA/Compactin0.920 0.920 0.870 0.580 0.310 0.360 0.500
Rpa2
KLA  Compactin  Compactin+KLA
 D00812 mRNA for 30-kDa subunit of replication protein A, complete cds. [D00812] KLA0.790 0.880 0.560 0.400 0.510 0.310 0.390
Compactin0.960 0.950 0.850 0.820 0.910 1.180 0.670
KLA/Compactin0.800 0.800 0.650 0.410 0.300 0.230 0.390
Rpa2
KLA  Compactin  Compactin+KLA
 NM_011284 replication protein A2 (Rpa2), mRNA [NM_011284] KLA0.940 0.870 0.720 0.430 0.450 0.390 0.410
Compactin0.900 0.990 0.880 1.060 0.950 1.040 0.760
KLA/Compactin0.910 0.970 0.690 0.460 0.390 0.310 0.370
Rpa3
KLA  Compactin  Compactin+KLA
 146141223 replication protein A3 KLA0.900 0.900 0.700 0.910 0.450 0.440 0.570
Compactin1.020 0.990 0.950 0.930 0.980 1.000 0.760
KLA/Compactin0.770 0.850 0.750 0.680 0.560 0.450 0.460
Rpa3
KLA  Compactin  Compactin+KLA
 NM_026632 replication protein A3 (Rpa3), mRNA [NM_026632] KLA0.950 0.990 0.810 1.030 0.550 0.490 0.580
Compactin1.090 1.090 0.980 1.210 1.040 0.960 0.850
KLA/Compactin1.020 0.990 0.830 0.870 0.550 0.520 0.490
Ssbp1
KLA  Compactin  Compactin+KLA
 NM_028358 single-stranded DNA binding protein 1 (Ssbp1), transcript variant 2, mRNA [NM_028358] KLA0.880 0.830 0.840 0.960 0.720 0.700 0.630
Compactin0.870 0.910 0.830 0.830 0.880 0.890 1.030
KLA/Compactin0.770 0.830 0.860 0.900 0.790 0.610 0.480
Ssbp1
KLA  Compactin  Compactin+KLA
 NM_028358 single-stranded DNA binding protein 1 (Ssbp1), transcript variant 2, mRNA [NM_028358] KLA0.990 0.940 0.990 1.020 0.740 0.650 0.570
Compactin1.080 1.030 1.040 1.120 1.040 1.100 0.920
KLA/Compactin0.940 0.990 0.930 1.020 0.770 0.770 0.470
Ssbp1
KLA  Compactin  Compactin+KLA
 NM_212468 single-stranded DNA binding protein 1 (Ssbp1), transcript variant 1, mRNA [NM_212468] KLA0.930 0.980 0.980 1.000 0.890 0.840 0.860
Compactin1.000 1.010 1.010 1.090 1.050 0.970 1.010
KLA/Compactin0.940 0.920 1.000 0.960 0.920 0.770 0.790
Ssbp1
KLA  Compactin  Compactin+KLA
 NM_212468 single-stranded DNA binding protein 1 (Ssbp1), transcript variant 1, mRNA [NM_212468] KLA1.000 0.970 1.000 0.930 0.960 0.870 0.840
Compactin0.980 0.990 0.970 0.960 0.970 0.970 0.930
KLA/Compactin0.900 0.920 0.990 0.930 0.960 0.730 0.780