Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

Introduction | Search by fold change ratio | Search by KEGG pathway | Search by LIPID MAPS lipid pathway

Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Pantothenate and CoA biosynthesis (mmu00770)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Aasdhppt
KLA  Compactin  Compactin+KLA
 AK144671 lung RCB-0558 LLC cDNA, RIKEN full-length enriched library, clone:G730021M24 product:aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase, full insert sequence [AK144671] KLA0.980 0.990 1.050 0.970 0.630 0.530 0.540
Compactin1.140 1.060 1.070 1.070 1.030 1.000 0.960
KLA/Compactin1.050 0.920 1.010 0.980 0.670 0.510 0.490
Aasdhppt
KLA  Compactin  Compactin+KLA
 NM_026276 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (Aasdhppt), mRNA [NM_026276] KLA0.890 0.940 0.950 1.000 0.620 0.680 0.830
Compactin0.960 0.940 0.970 1.070 0.980 0.890 0.910
KLA/Compactin0.910 0.900 0.840 0.820 0.720 0.800 0.730
Aasdhppt
KLA  Compactin  Compactin+KLA
 NM_026276 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (Aasdhppt), mRNA [NM_026276] KLA1.000 0.920 0.970 0.980 0.590 0.550 0.540
Compactin1.080 1.000 1.060 1.190 0.900 0.960 0.990
KLA/Compactin1.060 0.960 0.980 0.990 0.690 0.590 0.480
Bcat1
KLA  Compactin  Compactin+KLA
 NM_001024468 branched chain aminotransferase 1, cytosolic (Bcat1), transcript variant 1, mRNA [NM_001024468] KLA0.940 0.970 1.050 1.110 1.300 1.350 1.170
Compactin1.000 1.030 1.040 1.130 1.040 1.010 0.990
KLA/Compactin0.980 1.090 1.300 1.320 1.440 1.190 1.100
Bcat1
KLA  Compactin  Compactin+KLA
 NM_001024468 branched chain aminotransferase 1, cytosolic (Bcat1), transcript variant 1, mRNA [NM_001024468] KLA1.030 1.060 1.080 1.300 1.770 1.550 1.210
Compactin1.000 1.080 1.130 1.180 1.030 0.970 1.440
KLA/Compactin1.040 1.070 1.100 1.630 1.600 1.160 1.000
Bcat2
KLA  Compactin  Compactin+KLA
 NM_009737 branched chain aminotransferase 2, mitochondrial (Bcat2), nuclear gene encoding mitochondrial protein, mRNA [NM_009737] KLA0.780 1.010 1.170 1.070 0.900 1.000 1.090
Compactin1.020 1.090 1.110 1.080 1.050 1.370 0.980
KLA/Compactin1.010 0.990 1.050 1.020 0.960 1.080 1.130
Bcat2
KLA  Compactin  Compactin+KLA
 NM_009737 branched chain aminotransferase 2, mitochondrial (Bcat2), nuclear gene encoding mitochondrial protein, mRNA [NM_009737] KLA0.860 1.010 1.000 1.020 0.950 0.970 1.050
Compactin1.030 1.040 0.960 1.130 1.120 1.240 0.990
KLA/Compactin0.960 1.040 0.880 0.980 1.000 1.050 1.130
Bcat2
KLA  Compactin  Compactin+KLA
 NM_009737 branched chain aminotransferase 2, mitochondrial (Bcat2), nuclear gene encoding mitochondrial protein, mRNA [NM_009737] KLA1.020 2.730 1.000 1.010 0.990 0.950 1.010
Compactin1.050 0.960 0.960 0.990 0.950 0.950 0.990
KLA/Compactin1.030 1.000 1.030 1.000 0.970 0.920 0.980
Coasy
KLA  Compactin  Compactin+KLA
 NM_027896 Coenzyme A synthase (Coasy), mRNA [NM_027896] KLA0.880 0.930 0.830 0.620 0.870 1.380 1.380
Compactin0.880 0.900 1.090 0.960 0.980 0.900 1.050
KLA/Compactin0.900 0.910 0.910 0.700 0.890 1.300 1.230
Dpyd
KLA  Compactin  Compactin+KLA
 NM_170778 dihydropyrimidine dehydrogenase (Dpyd), mRNA [NM_170778] KLA1.080 0.980 0.940 0.970 1.000 1.040 1.030
Compactin0.890 1.070 0.960 1.050 0.920 0.970 0.990
KLA/Compactin0.930 0.940 1.010 1.010 0.980 0.980 1.020
Dpys
KLA  Compactin  Compactin+KLA
 NM_022722 dihydropyrimidinase (Dpys), mRNA [NM_022722] KLA0.980 1.000 1.020 1.030 1.020 1.020 1.100
Compactin1.050 0.960 0.990 0.930 1.020 1.020 0.960
KLA/Compactin0.990 1.030 0.880 0.970 1.080 1.040 1.040
Enpp1
KLA  Compactin  Compactin+KLA
 NM_008813 ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1), mRNA [NM_008813] KLA1.000 0.960 0.990 1.020 1.000 1.060 1.050
Compactin0.990 0.960 1.020 1.040 1.030 0.970 0.900
KLA/Compactin0.980 0.920 1.010 0.980 1.030 0.940 1.040
Enpp3
KLA  Compactin  Compactin+KLA
 BC005527 ectonucleotide pyrophosphatase [BC005527] KLA0.920 1.020 1.040 1.060 1.020 0.930 0.960
Compactin1.020 0.990 1.060 1.000 1.040 0.970 0.970
KLA/Compactin1.050 1.030 1.030 0.950 0.980 1.050 0.940
Enpp3
KLA  Compactin  Compactin+KLA
 BC006944 ectonucleotide pyrophosphatase/phosphodiesterase 3, mRNA (cDNA clone IMAGE:2655671), complete cds. [BC006944] KLA0.960 1.010 0.990 1.000 1.010 1.090 1.040
Compactin0.960 1.020 1.010 1.020 0.970 1.010 1.070
KLA/Compactin0.990 1.020 1.060 1.020 1.030 1.040 1.040
Enpp3
KLA  Compactin  Compactin+KLA
 BC006944 ectonucleotide pyrophosphatase/phosphodiesterase 3, mRNA (cDNA clone IMAGE:2655671), complete cds. [BC006944] KLA1.030 1.010 1.010 0.980 1.050 1.050 1.040
Compactin1.030 1.030 0.970 0.980 1.020 0.970 0.940
KLA/Compactin0.970 1.010 0.960 1.090 1.040 1.110 1.090
Enpp3
KLA  Compactin  Compactin+KLA
 NM_134005 ectonucleotide pyrophosphatase/phosphodiesterase 3 (Enpp3), mRNA [NM_134005] KLA0.970 1.000 0.950 0.970 0.990 1.090 1.010
Compactin0.970 1.040 1.000 1.000 1.010 1.000 1.080
KLA/Compactin1.020 0.990 1.000 1.020 0.980 0.960 1.050
Pank1
KLA  Compactin  Compactin+KLA
 AK019493 0 day neonate skin cDNA, RIKEN full-length enriched library, clone:4632412I06 product:hypothetical protein, full insert sequence. [AK019493] KLA1.000 1.000 1.030 0.970 1.040 1.030 0.990
Compactin0.870 1.030 0.990 1.020 0.920 0.970 1.070
KLA/Compactin1.020 0.960 1.030 1.030 1.040 1.000 0.920
Pank1
KLA  Compactin  Compactin+KLA
 NM_023792 pantothenate kinase 1 (Pank1), transcript variant 2, mRNA [NM_023792] KLA1.160 1.130 0.970 0.800 0.690 0.780 0.850
Compactin1.190 1.130 1.120 1.270 1.040 0.960 0.950
KLA/Compactin1.210 1.230 0.980 0.750 0.740 0.770 0.780
Pank2
KLA  Compactin  Compactin+KLA
 23943833 pantothenate kinase 2 (Hallervorden-Spatz syndrome) KLA0.990 0.980 1.010 1.090 1.000 1.140 1.100
Compactin1.040 1.060 0.970 1.210 0.930 1.040 1.020
KLA/Compactin1.040 1.020 1.050 1.140 1.080 1.140 1.140
Pank2
KLA  Compactin  Compactin+KLA
 NM_153501 pantothenate kinase 2 (Hallervorden-Spatz syndrome) (Pank2), nuclear gene encoding mitochondrial protein, mRNA [NM_153501] KLA0.920 0.960 0.990 0.970 0.990 1.160 1.210
Compactin0.890 0.980 0.950 0.970 0.970 1.070 1.000
KLA/Compactin0.870 0.890 0.950 1.060 1.090 1.300 1.290
Pank3
KLA  Compactin  Compactin+KLA
 NM_145962 pantothenate kinase 3 (Pank3), mRNA [NM_145962] KLA1.030 1.050 1.210 0.890 0.760 0.960 1.070
Compactin1.050 0.990 0.880 1.100 0.890 0.940 0.960
KLA/Compactin1.010 1.060 1.270 0.770 0.910 0.940 1.130
Pank4
KLA  Compactin  Compactin+KLA
 NM_172990 pantothenate kinase 4 (Pank4), mRNA [NM_172990] KLA1.250 1.060 0.990 0.820 0.780 1.050 1.100
Compactin1.230 1.170 1.200 1.170 1.110 0.990 0.880
KLA/Compactin1.310 1.180 0.970 1.060 0.850 0.850 0.990
Ppcdc
KLA  Compactin  Compactin+KLA
 NM_176831 phosphopantothenoylcysteine decarboxylase (Ppcdc), mRNA [NM_176831] KLA0.920 0.900 0.790 0.750 0.740 0.690 0.650
Compactin1.110 1.060 1.000 1.000 1.010 1.020 1.000
KLA/Compactin0.940 0.880 0.780 0.700 0.660 0.650 0.640
Ppcdc
KLA  Compactin  Compactin+KLA
 NM_176831 phosphopantothenoylcysteine decarboxylase (Ppcdc), mRNA [NM_176831] KLA1.310 0.960 0.940 0.600 0.590 0.870 0.730
Compactin1.070 1.270 1.220 1.030 0.870 0.920 1.110
KLA/Compactin1.070 0.850 0.920 0.710 0.520 0.690 0.460
Ppcs
KLA  Compactin  Compactin+KLA
 NM_026494 phosphopantothenoylcysteine synthetase (Ppcs), mRNA [NM_026494] KLA1.040 0.760 0.710 0.750 0.870 0.840 0.500
Compactin1.150 1.200 1.300 1.310 1.020 0.990 0.870
KLA/Compactin0.970 0.700 0.810 0.840 0.870 0.620 0.450
Upb1
KLA  Compactin  Compactin+KLA
 NM_133995 ureidopropionase, beta (Upb1), mRNA [NM_133995] KLA0.940 0.990 1.060 0.960 1.000 1.070 0.990
Compactin0.930 0.970 1.070 1.070 1.010 1.000 1.010
KLA/Compactin1.000 0.980 1.020 1.050 0.980 0.990 1.000
Upb1
KLA  Compactin  Compactin+KLA
 NM_133995 ureidopropionase, beta (Upb1), mRNA [NM_133995] KLA0.960 1.020 1.020 1.060 0.990 1.010 1.040
Compactin0.970 1.040 0.970 1.030 1.010 0.950 1.070
KLA/Compactin0.970 1.040 1.040 1.060 1.050 1.000 1.020
Vnn1
KLA  Compactin  Compactin+KLA
 NM_011704 vanin 1 (Vnn1), mRNA [NM_011704] KLA1.010 1.050 1.070 1.000 0.990 0.950 1.040
Compactin1.030 1.020 1.030 1.050 1.080 1.080 1.030
KLA/Compactin0.970 1.040 0.990 0.990 1.030 0.990 0.980