Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Vitamin B6 metabolism (mmu00750)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Aox1
KLA  Compactin  Compactin+KLA
 NM_009676 aldehyde oxidase 1 (Aox1), mRNA [NM_009676] KLA0.970 1.000 1.030 1.060 1.040 1.050 1.060
Compactin0.960 1.050 0.990 1.090 1.100 0.960 0.990
KLA/Compactin0.980 1.000 0.970 0.920 1.040 1.040 0.980
Aox3
KLA  Compactin  Compactin+KLA
 NM_023617 aldehyde oxidase 3 (Aox3), mRNA [NM_023617] KLA1.010 0.970 0.990 1.000 0.920 0.970 1.030
Compactin0.960 0.960 1.020 0.960 0.950 1.010 1.050
KLA/Compactin1.020 1.010 1.070 1.020 1.020 0.970 1.010
Aox4
KLA  Compactin  Compactin+KLA
 NM_023631 aldehyde oxidase 4 (Aox4), mRNA [NM_023631] KLA0.950 1.030 1.020 1.000 0.970 0.910 1.080
Compactin1.090 1.070 1.020 1.030 1.020 1.040 0.990
KLA/Compactin0.990 1.080 1.070 0.960 1.000 1.010 1.000
Pdxk
KLA  Compactin  Compactin+KLA
 NM_172134 pyridoxal (pyridoxine, vitamin B6) kinase (Pdxk), mRNA [NM_172134] KLA0.910 1.020 1.040 0.960 0.760 1.000 1.980
Compactin0.950 1.010 0.930 1.090 0.840 0.860 0.700
KLA/Compactin0.890 1.040 0.960 0.890 0.700 0.840 1.700
Pdxk
KLA  Compactin  Compactin+KLA
 NM_172134 pyridoxal (pyridoxine, vitamin B6) kinase (Pdxk), mRNA [NM_172134] KLA0.930 0.760 0.540 0.290 0.450 0.430 0.660
Compactin0.840 0.920 0.880 0.790 0.890 0.660 0.470
KLA/Compactin0.840 0.860 0.470 0.220 0.330 0.410 0.840
Pdxk
KLA  Compactin  Compactin+KLA
 NM_172134 pyridoxal (pyridoxine, vitamin B6) kinase (Pdxk), mRNA [NM_172134] KLA1.150 1.090 1.180 1.190 0.910 1.040 1.900
Compactin1.180 1.160 1.190 1.150 0.870 0.850 0.690
KLA/Compactin1.030 0.940 1.060 0.990 0.720 0.810 1.600
Pdxk
KLA  Compactin  Compactin+KLA
 NM_172134 pyridoxal (pyridoxine, vitamin B6) kinase (Pdxk), mRNA [NM_172134] KLA1.310 1.110 0.680 0.380 0.630 0.580 0.940
Compactin1.290 1.300 1.270 1.230 0.950 0.760 0.610
KLA/Compactin1.350 0.990 0.680 0.360 0.440 0.400 0.750
Pdxp
KLA  Compactin  Compactin+KLA
 85838507 pyridoxal (pyridoxine, vitamin B6) phosphatase KLA1.030 0.940 0.350 0.280 0.370 0.280 0.430
Compactin0.960 1.150 1.140 0.870 1.160 1.120 0.900
KLA/Compactin0.960 1.200 0.410 0.240 0.280 0.250 0.550
Pdxp
KLA  Compactin  Compactin+KLA
 NM_020271 pyridoxal (pyridoxine, vitamin B6) phosphatase (Pdxp), mRNA [NM_020271] KLA0.890 0.980 0.480 0.340 0.390 0.400 0.640
Compactin0.940 0.960 1.080 0.930 1.190 1.280 0.970
KLA/Compactin0.970 1.100 0.490 0.400 0.360 0.360 0.630
Phospho2
KLA  Compactin  Compactin+KLA
 AK010147 adult male tongue cDNA, RIKEN full-length enriched library, clone:2310074E15 product:unclassifiable, full insert sequence. [AK010147] KLA0.980 0.990 0.990 0.940 1.010 1.000 0.930
Compactin0.980 0.960 1.030 0.960 0.910 1.000 1.070
KLA/Compactin1.030 0.930 0.980 0.970 1.010 0.950 1.030
Phospho2
KLA  Compactin  Compactin+KLA
 NM_028521 phosphatase, orphan 2 (Phospho2), mRNA [NM_028521] KLA0.940 0.810 1.030 1.210 1.210 1.180 1.270
Compactin1.040 1.070 1.030 1.170 1.000 0.940 1.040
KLA/Compactin1.060 0.920 0.920 1.270 1.170 1.200 1.200
Pnpo
KLA  Compactin  Compactin+KLA
 NM_134021 pyridoxine 5-phosphate oxidase (Pnpo), mRNA [NM_134021] KLA1.140 1.090 0.910 0.820 0.790 0.940 1.080
Compactin1.050 1.190 1.220 1.100 1.150 0.880 0.930
KLA/Compactin1.040 0.980 0.970 0.870 0.700 0.740 0.750
Psat1
KLA  Compactin  Compactin+KLA
 NM_177420 phosphoserine aminotransferase 1 (Psat1), mRNA [NM_177420] KLA1.330 0.980 1.010 0.860 1.310 1.430 0.940
Compactin1.090 1.090 1.140 1.160 1.210 1.230 1.290
KLA/Compactin1.160 1.060 0.980 1.100 1.270 1.170 1.120