Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Riboflavin metabolism (mmu00740)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Acp1
KLA  Compactin  Compactin+KLA
 159032061 acid phosphatase 1, soluble KLA0.920 0.970 1.020 1.040 1.030 0.880 1.010
Compactin1.060 1.080 1.020 1.010 1.010 0.970 0.980
KLA/Compactin1.020 0.970 0.940 0.990 1.090 1.010 1.020
Acp1
KLA  Compactin  Compactin+KLA
 NM_001110239 acid phosphatase 1, soluble (Acp1), transcript variant 1, mRNA [NM_001110239] KLA0.920 0.940 1.020 1.050 0.900 0.940 1.480
Compactin0.940 0.950 1.030 1.140 0.890 0.910 0.850
KLA/Compactin1.020 0.950 0.980 0.990 0.930 0.990 1.420
Acp2
KLA  Compactin  Compactin+KLA
 AK170658 NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630113A07 product:acid phosphatase 2, lysosomal, full insert sequence [AK170658] KLA1.140 0.960 1.030 0.920 1.030 0.870 0.730
Compactin1.100 1.040 0.980 1.030 0.910 0.880 0.950
KLA/Compactin1.190 1.020 0.980 0.960 0.950 0.850 0.670
Acp2
KLA  Compactin  Compactin+KLA
 NM_007387 acid phosphatase 2, lysosomal (Acp2), mRNA [NM_007387] KLA0.940 1.110 1.210 1.140 1.060 1.310 1.000
Compactin0.950 1.050 0.900 0.970 0.930 0.940 1.060
KLA/Compactin1.010 0.980 1.040 1.230 1.220 1.340 1.280
Acp2
KLA  Compactin  Compactin+KLA
 NM_007387 acid phosphatase 2, lysosomal (Acp2), mRNA [NM_007387] KLA0.950 0.970 1.110 1.110 1.110 1.110 1.050
Compactin0.970 0.990 0.950 1.020 1.000 1.010 1.030
KLA/Compactin1.070 1.020 1.100 1.080 1.180 1.200 1.070
Acp5
KLA  Compactin  Compactin+KLA
 NM_007388 acid phosphatase 5, tartrate resistant (Acp5), transcript variant 3, mRNA [NM_007388] KLA1.090 1.250 1.470 1.510 1.220 1.110 1.120
Compactin1.090 1.040 1.090 1.140 0.930 0.730 0.640
KLA/Compactin1.180 1.320 1.340 1.290 0.940 0.810 0.610
Acp6
KLA  Compactin  Compactin+KLA
 NM_019800 acid phosphatase 6, lysophosphatidic (Acp6), mRNA [NM_019800] KLA0.860 0.950 0.910 0.710 0.540 0.690 1.000
Compactin1.100 1.000 1.440 1.050 1.270 1.170 0.920
KLA/Compactin1.000 0.940 0.980 0.780 0.620 0.770 0.700
Acpp
KLA  Compactin  Compactin+KLA
 NM_019807 acid phosphatase, prostate (Acpp), transcript variant 2, mRNA [NM_019807] KLA1.030 1.020 1.060 1.130 1.130 1.260 1.180
Compactin0.960 0.970 1.040 1.030 1.080 1.050 1.060
KLA/Compactin0.910 1.110 0.990 1.100 1.240 1.230 1.240
Acpp
KLA  Compactin  Compactin+KLA
 NM_207668 acid phosphatase, prostate (Acpp), transcript variant 1, mRNA [NM_207668] KLA1.020 1.000 1.020 1.040 0.940 1.010 1.040
Compactin1.020 1.040 1.010 0.950 1.040 1.030 0.950
KLA/Compactin1.030 0.990 1.000 0.980 1.050 1.050 1.140
AK134499
KLA  Compactin  Compactin+KLA
 AK134499 11 days embryo head cDNA, RIKEN full-length enriched library, clone:6230419C23 product:unclassifiable, full insert sequence [AK134499] KLA1.060 1.000 0.970 0.970 1.040 1.040 1.010
Compactin1.030 1.020 0.940 1.020 0.940 0.990 1.000
KLA/Compactin1.030 0.940 0.950 1.000 0.910 0.940 1.040
Blvrb
KLA  Compactin  Compactin+KLA
 NM_144923 biliverdin reductase B (flavin reductase (NADPH)) (Blvrb), mRNA [NM_144923] KLA0.850 0.870 0.990 1.040 1.380 2.250 3.970
Compactin0.870 0.910 0.960 0.980 0.990 1.130 1.310
KLA/Compactin0.920 0.820 0.990 1.040 1.670 2.970 4.980
Enpp1
KLA  Compactin  Compactin+KLA
 NM_008813 ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1), mRNA [NM_008813] KLA1.000 0.960 0.990 1.020 1.000 1.060 1.050
Compactin0.990 0.960 1.020 1.040 1.030 0.970 0.900
KLA/Compactin0.980 0.920 1.010 0.980 1.030 0.940 1.040
Enpp3
KLA  Compactin  Compactin+KLA
 BC005527 ectonucleotide pyrophosphatase [BC005527] KLA0.920 1.020 1.040 1.060 1.020 0.930 0.960
Compactin1.020 0.990 1.060 1.000 1.040 0.970 0.970
KLA/Compactin1.050 1.030 1.030 0.950 0.980 1.050 0.940
Enpp3
KLA  Compactin  Compactin+KLA
 BC006944 ectonucleotide pyrophosphatase/phosphodiesterase 3, mRNA (cDNA clone IMAGE:2655671), complete cds. [BC006944] KLA0.960 1.010 0.990 1.000 1.010 1.090 1.040
Compactin0.960 1.020 1.010 1.020 0.970 1.010 1.070
KLA/Compactin0.990 1.020 1.060 1.020 1.030 1.040 1.040
Enpp3
KLA  Compactin  Compactin+KLA
 BC006944 ectonucleotide pyrophosphatase/phosphodiesterase 3, mRNA (cDNA clone IMAGE:2655671), complete cds. [BC006944] KLA1.030 1.010 1.010 0.980 1.050 1.050 1.040
Compactin1.030 1.030 0.970 0.980 1.020 0.970 0.940
KLA/Compactin0.970 1.010 0.960 1.090 1.040 1.110 1.090
Enpp3
KLA  Compactin  Compactin+KLA
 NM_134005 ectonucleotide pyrophosphatase/phosphodiesterase 3 (Enpp3), mRNA [NM_134005] KLA0.970 1.000 0.950 0.970 0.990 1.090 1.010
Compactin0.970 1.040 1.000 1.000 1.010 1.000 1.080
KLA/Compactin1.020 0.990 1.000 1.020 0.980 0.960 1.050
Flad1
KLA  Compactin  Compactin+KLA
 NM_177041 RFad1, flavin adenine dinucleotide synthetase, homolog (yeast) (Flad1), mRNA [NM_177041] KLA0.960 1.090 1.100 0.910 0.920 1.480 1.720
Compactin1.090 1.120 1.070 1.150 1.000 1.020 0.930
KLA/Compactin1.040 1.020 1.130 1.020 1.040 1.550 1.590
Rfk
KLA  Compactin  Compactin+KLA
 NM_019437 riboflavin kinase (Rfk), mRNA [NM_019437] KLA0.770 0.920 0.790 0.900 0.980 0.780 0.920
Compactin0.930 0.910 0.810 0.820 0.960 1.050 1.050
KLA/Compactin0.750 0.940 0.840 0.840 0.720 0.820 1.080
Rfk
KLA  Compactin  Compactin+KLA
 NM_019437 riboflavin kinase (Rfk), mRNA [NM_019437] KLA0.890 0.930 1.050 1.240 1.140 1.240 1.720
Compactin1.080 0.980 1.000 1.220 1.050 0.990 1.000
KLA/Compactin1.040 0.970 1.020 1.190 1.150 1.320 1.590
Rfk
KLA  Compactin  Compactin+KLA
 NM_019437 riboflavin kinase (Rfk), mRNA [NM_019437] KLA0.970 0.960 1.000 1.040 0.770 0.910 1.050
Compactin1.020 1.050 0.960 1.020 0.950 1.010 1.120
KLA/Compactin0.920 0.930 0.960 0.890 0.930 0.920 0.900
Tyr
KLA  Compactin  Compactin+KLA
 168823498 tyrosinase KLA1.080 0.990 1.030 0.910 0.980 0.960 1.020
Compactin1.060 1.010 1.000 1.020 1.000 1.020 1.030
KLA/Compactin1.030 1.050 0.960 0.970 1.010 1.000 0.980
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA0.930 0.950 1.000 0.890 1.010 1.020 1.010
Compactin0.960 0.930 1.020 0.940 0.960 1.090 1.040
KLA/Compactin1.020 0.940 0.950 1.000 1.030 0.940 0.990
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA0.940 1.000 1.020 0.930 0.980 1.110 0.940
Compactin0.930 1.030 1.000 1.000 0.950 0.960 1.080
KLA/Compactin0.930 1.030 1.010 0.930 0.970 0.960 1.030
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA0.970 0.970 0.990 0.990 1.050 1.040 1.000
Compactin0.920 1.050 1.020 1.000 0.970 0.900 1.020
KLA/Compactin0.980 0.970 0.990 0.980 0.990 0.990 0.980
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA0.970 1.050 0.950 1.010 1.000 1.040 1.040
Compactin1.020 1.000 1.020 1.020 0.990 1.030 1.060
KLA/Compactin0.980 1.020 0.970 0.950 0.990 1.020 0.980
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA0.980 0.970 0.950 1.060 0.970 0.980 1.010
Compactin0.980 0.990 1.040 1.050 0.960 1.030 0.980
KLA/Compactin1.020 1.030 1.030 0.980 1.070 0.940 0.980
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA0.990 1.030 0.990 0.910 1.010 1.100 1.000
Compactin0.970 0.960 0.990 1.040 0.960 1.020 1.020
KLA/Compactin1.040 1.000 1.020 0.940 0.950 0.970 1.040
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA0.990 1.030 0.990 0.960 1.020 1.000 1.060
Compactin1.000 1.010 0.940 1.020 0.950 1.030 0.990
KLA/Compactin0.960 1.060 1.010 0.950 1.020 1.000 1.000
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA0.990 1.040 1.040 1.050 1.050 0.990 0.950
Compactin1.000 1.000 1.040 1.010 1.040 0.970 0.970
KLA/Compactin1.060 1.050 0.970 1.010 0.990 0.970 0.960
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA1.010 1.040 0.980 1.000 0.940 1.020 1.010
Compactin1.070 0.970 1.120 1.010 1.000 1.030 1.030
KLA/Compactin0.990 1.050 1.000 0.940 0.990 1.030 1.000
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA1.020 0.960 1.030 0.990 1.020 0.990 1.060
Compactin0.980 1.000 1.020 1.010 1.070 1.020 0.940
KLA/Compactin1.070 0.990 1.020 1.050 1.030 0.940 1.050
Tyr
KLA  Compactin  Compactin+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA1.050 0.970 0.980 0.950 0.980 1.080 0.970
Compactin0.940 1.030 1.010 1.010 0.960 0.970 1.060
KLA/Compactin1.000 0.900 0.990 0.990 0.950 0.950 1.040