Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

Introduction | Search by fold change ratio | Search by KEGG pathway | Search by LIPID MAPS lipid pathway

Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: alpha-Linolenic acid metabolism (mmu00592)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Acaa1a
KLA  Compactin  Compactin+KLA
 NM_130864 acetyl-Coenzyme A acyltransferase 1A (Acaa1a), mRNA [NM_130864] KLA0.940 0.820 0.920 0.910 0.770 0.760 0.430
Compactin1.060 0.930 0.970 0.940 1.030 1.140 0.770
KLA/Compactin0.940 0.950 0.810 0.720 0.820 0.670 0.430
Acaa1a
KLA  Compactin  Compactin+KLA
 NM_130864 acetyl-Coenzyme A acyltransferase 1A (Acaa1a), mRNA [NM_130864] KLA1.080 0.910 0.980 0.920 0.690 0.730 0.430
Compactin1.050 1.020 1.010 1.150 0.930 1.130 0.760
KLA/Compactin1.030 0.930 0.900 0.890 0.780 0.860 0.400
Acaa1a
KLA  Compactin  Compactin+KLA
 NM_130864 acetyl-Coenzyme A acyltransferase 1A (Acaa1a), mRNA [NM_130864] KLA1.380 1.180 1.110 0.980 1.070 0.910 0.470
Compactin1.310 1.220 1.140 1.360 1.280 1.360 0.980
KLA/Compactin1.270 1.180 1.070 1.040 1.110 0.750 0.470
Acaa1b
KLA  Compactin  Compactin+KLA
 NM_146230 acetyl-Coenzyme A acyltransferase 1B (Acaa1b), mRNA [NM_146230] KLA1.220 1.210 1.050 1.140 0.910 0.840 0.570
Compactin1.260 1.090 1.250 1.250 1.160 1.140 0.800
KLA/Compactin1.280 0.760 1.190 1.140 0.930 0.770 0.550
Acox1
KLA  Compactin  Compactin+KLA
 NM_015729 acyl-Coenzyme A oxidase 1, palmitoyl (Acox1), mRNA [NM_015729] KLA0.850 1.000 0.960 0.910 1.320 1.320 1.570
Compactin0.980 1.050 0.990 0.970 0.980 1.060 1.020
KLA/Compactin1.020 0.930 0.970 1.050 1.180 1.510 2.020
Acox1
KLA  Compactin  Compactin+KLA
 NM_015729 acyl-Coenzyme A oxidase 1, palmitoyl (Acox1), mRNA [NM_015729] KLA0.950 0.890 0.850 0.660 1.220 1.090 0.790
Compactin0.960 1.060 1.070 1.120 1.060 0.960 0.930
KLA/Compactin0.980 0.870 0.820 0.660 1.170 1.180 0.800
Acox3
KLA  Compactin  Compactin+KLA
 34328333 acyl-Coenzyme A oxidase 3, pristanoyl KLA0.740 0.840 0.600 0.640 0.650 0.570 0.660
Compactin0.820 0.910 0.910 0.910 0.940 0.950 0.780
KLA/Compactin1.040 0.860 0.630 0.620 0.510 0.510 0.790
Acox3
KLA  Compactin  Compactin+KLA
 NM_030721 acyl-Coenzyme A oxidase 3, pristanoyl (Acox3), mRNA [NM_030721] KLA0.880 0.820 0.710 0.690 0.570 0.620 0.840
Compactin0.840 0.870 0.990 1.040 1.060 1.010 0.870
KLA/Compactin0.960 0.780 0.670 0.670 0.580 0.630 0.780
Fads2
KLA  Compactin  Compactin+KLA
 NM_019699 fatty acid desaturase 2 (Fads2), mRNA [NM_019699] KLA1.050 0.980 1.100 0.900 0.700 0.540 0.730
Compactin1.060 1.150 1.120 1.070 0.850 0.980 0.740
KLA/Compactin1.140 1.010 1.210 1.030 0.680 0.540 0.960
Hrasls3
KLA  Compactin  Compactin+KLA
 AK052657 0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630015C01 product:H-REV 107 PROTEIN homolog [Rattus norvegicus], full insert sequence. [AK052657] KLA1.040 1.020 0.990 1.050 0.990 0.960 1.020
Compactin1.030 0.990 1.010 0.960 0.980 0.970 0.970
KLA/Compactin1.000 1.020 1.020 1.000 1.030 0.980 0.970
Hrasls3
KLA  Compactin  Compactin+KLA
 NM_139269 HRAS like suppressor 3 (Hrasls3), mRNA [NM_139269] KLA0.910 1.050 1.000 1.220 1.000 0.780 0.890
Compactin1.030 1.010 0.970 0.990 1.030 1.020 1.280
KLA/Compactin0.950 0.990 0.960 1.180 1.110 1.040 0.900
Pla2g10
KLA  Compactin  Compactin+KLA
 NM_011987 phospholipase A2, group X (Pla2g10), mRNA [NM_011987] KLA0.970 0.980 1.040 1.030 1.030 0.990 1.020
Compactin0.980 0.920 1.060 0.910 0.980 1.020 1.000
KLA/Compactin0.970 0.930 0.960 0.990 0.990 0.950 1.000
Pla2g10
KLA  Compactin  Compactin+KLA
 NM_011987 phospholipase A2, group X (Pla2g10), mRNA [NM_011987] KLA1.010 0.910 0.980 0.980 1.060 1.010 0.960
Compactin0.990 1.010 0.990 0.920 1.090 1.060 0.950
KLA/Compactin1.070 1.040 1.000 1.050 1.040 0.970 1.010
Pla2g12a
KLA  Compactin  Compactin+KLA
 NM_023196 phospholipase A2, group XIIA (Pla2g12a), transcript variant 1, mRNA [NM_023196] KLA1.090 1.060 1.100 1.160 1.110 1.150 2.510
Compactin1.150 1.210 1.130 1.290 1.060 1.140 1.070
KLA/Compactin0.950 1.160 0.990 1.260 1.090 1.430 2.730
Pla2g12a
KLA  Compactin  Compactin+KLA
 NM_183423 phospholipase A2, group XIIA (Pla2g12a), transcript variant 2, mRNA [NM_183423] KLA1.140 1.180 1.080 1.210 1.150 1.300 2.370
Compactin1.130 1.290 1.180 1.180 1.150 1.080 1.080
KLA/Compactin1.040 1.120 1.180 1.200 1.200 1.490 2.800
Pla2g12b
KLA  Compactin  Compactin+KLA
 NM_023530 phospholipase A2, group XIIB (Pla2g12b), mRNA [NM_023530] KLA0.940 1.050 0.970 1.050 0.970 1.010 0.990
Compactin0.980 1.040 1.030 1.050 1.010 0.990 1.130
KLA/Compactin0.960 1.030 0.990 1.050 1.030 0.940 1.040
Pla2g1b
KLA  Compactin  Compactin+KLA
 NM_011107 phospholipase A2, group IB, pancreas (Pla2g1b), mRNA [NM_011107] KLA1.050 1.000 0.970 0.930 1.000 1.000 1.080
Compactin1.200 1.030 1.050 0.980 1.010 1.000 0.960
KLA/Compactin0.930 1.010 0.950 1.040 1.020 0.940 1.000
Pla2g2a
KLA  Compactin  Compactin+KLA
 NM_001082531 phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), mRNA [NM_001082531] KLA1.040 1.000 1.030 1.020 0.970 0.910 1.000
Compactin0.960 0.970 1.010 0.940 0.980 1.010 0.890
KLA/Compactin1.020 0.990 1.000 0.940 1.010 1.030 0.990
Pla2g2c
KLA  Compactin  Compactin+KLA
 NM_008868 phospholipase A2, group IIC (Pla2g2c), mRNA [NM_008868] KLA1.030 0.970 1.000 0.990 0.960 1.080 0.990
Compactin1.030 0.970 0.930 0.950 0.930 0.980 1.040
KLA/Compactin0.990 0.940 1.020 1.040 0.960 0.900 1.020
Pla2g2d
KLA  Compactin  Compactin+KLA
 118130231 phospholipase A2, group IID KLA0.980 1.040 1.050 0.990 1.060 1.050 1.000
Compactin0.920 1.080 1.000 0.960 1.000 1.000 1.140
KLA/Compactin0.950 0.880 0.950 0.990 1.010 1.010 1.000
Pla2g2d
KLA  Compactin  Compactin+KLA
 NM_011109 phospholipase A2, group IID (Pla2g2d), mRNA [NM_011109] KLA1.000 0.970 0.980 0.930 0.970 0.940 0.950
Compactin0.940 0.960 0.990 0.950 1.040 0.980 0.980
KLA/Compactin1.000 0.990 1.040 0.940 0.950 0.970 1.000
Pla2g2e
KLA  Compactin  Compactin+KLA
 NM_012044 phospholipase A2, group IIE (Pla2g2e), mRNA [NM_012044] KLA0.870 0.940 0.930 1.020 0.970 0.980 1.200
Compactin1.010 0.950 0.980 0.950 0.960 0.890 0.870
KLA/Compactin0.990 1.000 0.930 0.950 0.970 0.910 0.880
Pla2g2f
KLA  Compactin  Compactin+KLA
 NM_012045 phospholipase A2, group IIF (Pla2g2f), mRNA [NM_012045] KLA1.070 0.930 0.990 1.050 0.970 1.010 0.980
Compactin1.040 0.990 1.030 1.020 1.050 1.010 1.020
KLA/Compactin0.930 0.990 0.980 1.020 1.030 1.050 1.020
Pla2g3
KLA  Compactin  Compactin+KLA
 NM_172791 phospholipase A2, group III (Pla2g3), mRNA [NM_172791] KLA1.060 0.950 0.980 1.030 1.000 0.990 1.060
Compactin0.890 0.900 0.970 0.960 0.980 1.010 0.960
KLA/Compactin0.990 0.990 0.970 0.980 0.980 1.190 1.010
Pla2g4a
KLA  Compactin  Compactin+KLA
 NM_008869 phospholipase A2, group IVA (cytosolic, calcium-dependent) (Pla2g4a), mRNA [NM_008869] KLA1.050 0.920 0.600 0.730 2.040 1.590 1.240
Compactin0.860 1.020 0.940 0.740 1.140 1.460 1.320
KLA/Compactin0.950 0.960 0.880 0.840 1.120 2.120 2.150
Pla2g4a
KLA  Compactin  Compactin+KLA
 NM_008869 phospholipase A2, group IVA (cytosolic, calcium-dependent) (Pla2g4a), mRNA [NM_008869] KLA1.310 1.200 0.950 0.960 1.630 1.580 1.570
Compactin1.230 1.110 1.090 1.290 1.160 1.120 1.290
KLA/Compactin1.300 1.220 0.900 0.950 1.940 1.960 1.850
Pla2g4b
KLA  Compactin  Compactin+KLA
 NM_145378 phospholipase A2, group IVB (cytosolic) (Pla2g4b), mRNA [NM_145378] KLA0.910 0.840 0.840 1.320 1.150 1.460 1.400
Compactin0.990 1.020 1.060 1.010 1.170 1.010 1.080
KLA/Compactin0.980 0.870 0.700 1.500 1.320 1.350 1.320
Pla2g4b
KLA  Compactin  Compactin+KLA
 NM_145378 phospholipase A2, group IVB (cytosolic) (Pla2g4b), mRNA [NM_145378] KLA1.030 0.840 0.890 1.040 0.970 1.050 1.180
Compactin0.930 0.940 1.050 1.000 1.080 1.030 1.080
KLA/Compactin1.000 0.910 0.950 1.160 1.020 1.070 1.090
Pla2g4c
KLA  Compactin  Compactin+KLA
 AK145339 1 cell embryo 1 cell cDNA, RIKEN full-length enriched library, clone:I0C0013F18 product:weakly similar to Cytosolic phospholipase A2 gamma [Homo sapiens], full insert sequence [AK145339] KLA1.090 1.010 1.020 1.060 1.100 1.100 1.110
Compactin0.930 1.020 0.960 0.960 1.090 0.970 1.090
KLA/Compactin1.010 1.090 1.070 1.040 1.160 1.020 1.120
Pla2g4c
KLA  Compactin  Compactin+KLA
 NM_001004762 phospholipase A2, group IVC (cytosolic, calcium-independent) (Pla2g4c), mRNA [NM_001004762] KLA1.070 1.100 1.160 0.890 1.000 1.140 0.970
Compactin0.910 0.990 0.970 0.960 0.890 1.020 1.110
KLA/Compactin1.030 1.010 0.960 0.990 0.990 0.890 1.010
Pla2g4d
KLA  Compactin  Compactin+KLA
 67906182 phospholipase A2, group IVD KLA1.010 0.980 0.990 1.010 0.990 1.280 1.030
Compactin1.000 1.060 0.940 1.050 0.990 1.030 1.020
KLA/Compactin0.930 0.970 0.970 1.010 0.990 1.090 1.020
Pla2g4e
KLA  Compactin  Compactin+KLA
 AK049063 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230096D22 product:hypothetical Lysophospholipase catalytic domain containing protein, full insert sequence. [AK049063] KLA1.020 1.040 1.050 1.800 1.020 0.990 1.120
Compactin1.060 1.020 1.070 1.000 0.970 0.990 0.970
KLA/Compactin1.000 1.030 1.030 1.020 1.020 1.030 0.980
Pla2g4e
KLA  Compactin  Compactin+KLA
 NM_177845 phospholipase A2, group IVE (Pla2g4e), mRNA [NM_177845] KLA0.900 1.000 1.080 0.940 0.990 1.000 1.020
Compactin0.910 1.000 0.940 0.960 1.070 1.030 1.010
KLA/Compactin1.080 1.040 1.060 0.960 0.970 0.990 1.070
Pla2g4f
KLA  Compactin  Compactin+KLA
 NM_001024145 phospholipase A2, group IVF (Pla2g4f), mRNA [NM_001024145] KLA1.100 0.980 1.030 1.020 1.000 0.970 1.010
Compactin1.050 0.990 0.980 1.040 1.000 1.000 0.990
KLA/Compactin1.020 0.960 0.940 1.030 1.040 1.030 0.990
Pla2g5
KLA  Compactin  Compactin+KLA
 NM_011110 phospholipase A2, group V (Pla2g5), transcript variant 2, mRNA [NM_011110] KLA0.950 1.620 2.030 2.680 3.750 5.560 13.250
Compactin0.930 1.020 1.030 0.900 0.780 0.870 1.960
KLA/Compactin0.970 1.540 1.900 2.870 3.370 5.780 11.040
Pla2g6
KLA  Compactin  Compactin+KLA
 NM_016915 phospholipase A2, group VI (Pla2g6), mRNA [NM_016915] KLA0.840 1.270 1.160 0.930 1.740 1.510 1.310
Compactin0.900 0.920 0.960 0.880 0.940 1.080 1.040
KLA/Compactin0.930 1.320 1.260 1.020 1.390 1.500 1.260
Plb1
KLA  Compactin  Compactin+KLA
 124487226 phospholipase B1 KLA0.990 1.000 1.020 1.000 0.970 1.070 1.020
Compactin0.950 0.990 1.050 1.000 0.950 1.030 1.070
KLA/Compactin1.030 0.980 0.950 0.940 0.940 0.910 0.970
Plb1
KLA  Compactin  Compactin+KLA
 AK015993 adult male testis cDNA, RIKEN full-length enriched library, clone:4930539A06 product:weakly similar to PHOSPHOLIPASE B [Rattus norvegicus], full insert sequence. [AK015993] KLA0.960 0.940 1.030 1.030 0.990 0.930 0.990
Compactin1.060 1.000 0.950 0.950 1.080 1.010 1.000
KLA/Compactin1.000 1.050 1.090 1.020 1.000 0.980 1.030
Plb1
KLA  Compactin  Compactin+KLA
 NM_001081407 phospholipase B1 (Plb1), mRNA [NM_001081407] KLA0.970 0.960 0.930 1.050 0.960 1.000 1.030
Compactin0.960 0.950 1.010 0.960 0.960 1.030 0.890
KLA/Compactin0.860 0.990 1.010 1.000 0.940 1.020 1.020
Plb1
KLA  Compactin  Compactin+KLA
 NM_001081407 phospholipase B1 (Plb1), mRNA [NM_001081407] KLA1.070 1.010 1.080 1.030 0.960 1.020 1.030
Compactin1.000 1.030 1.030 0.990 1.020 0.950 0.980
KLA/Compactin1.020 1.010 1.020 1.020 1.030 1.060 0.930