Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Glycosaminoglycan degradation (mmu00531)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
AK209324
KLA  Compactin  Compactin+KLA
 AK209324 cDNA, clone:Y2G0114L23, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000060207, based on BLAT search. [AK209324] KLA0.880 0.650 1.030 0.930 1.150 0.940 0.680
Compactin1.180 1.090 1.030 0.970 1.050 0.980 0.980
KLA/Compactin0.950 0.650 0.990 0.860 1.040 0.700 0.560
Arsb
KLA  Compactin  Compactin+KLA
 AK083309 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920003D12 product:arylsulfatase B structural, full insert sequence. [AK083309] KLA1.010 0.960 1.120 1.070 1.030 0.980 0.950
Compactin1.050 1.000 1.010 1.040 1.070 1.010 0.930
KLA/Compactin1.040 1.010 0.910 0.930 0.960 0.930 0.950
Arsb
KLA  Compactin  Compactin+KLA
 NM_009712 arylsulfatase B (Arsb), mRNA [NM_009712] KLA0.910 1.130 1.350 1.020 0.880 0.680 0.690
Compactin1.100 1.030 1.130 1.080 1.090 1.200 1.130
KLA/Compactin1.130 1.080 1.280 1.110 0.820 0.780 0.670
Arsb
KLA  Compactin  Compactin+KLA
 NM_009712 arylsulfatase B (Arsb), mRNA [NM_009712] KLA1.000 1.060 1.030 1.080 0.790 0.700 0.560
Compactin1.030 1.060 1.030 0.980 1.090 1.200 1.040
KLA/Compactin1.080 1.120 0.970 0.950 0.810 0.670 0.570
Galns
KLA  Compactin  Compactin+KLA
 NM_016722 galactosamine (N-acetyl)-6-sulfate sulfatase (Galns), mRNA [NM_016722] KLA0.970 1.020 0.940 1.000 1.000 1.090 2.180
Compactin0.980 0.920 1.020 0.830 1.020 0.970 1.080
KLA/Compactin1.020 1.000 1.040 0.900 0.910 1.310 2.730
Glb1
KLA  Compactin  Compactin+KLA
 NM_009752 galactosidase, beta 1 (Glb1), mRNA [NM_009752] KLA0.930 0.960 1.060 0.950 0.970 1.000 1.320
Compactin1.010 0.960 1.020 1.050 0.970 0.990 1.030
KLA/Compactin1.130 0.950 1.020 0.990 0.900 0.950 1.210
Glb1
KLA  Compactin  Compactin+KLA
 NM_009752 galactosidase, beta 1 (Glb1), mRNA [NM_009752] KLA1.130 1.140 1.090 1.050 0.940 1.080 1.350
Compactin1.220 1.150 1.170 1.250 0.990 1.110 1.160
KLA/Compactin1.290 1.170 1.160 0.940 0.940 1.050 1.180
Glb1
KLA  Compactin  Compactin+KLA
 NM_009752 galactosidase, beta 1 (Glb1), mRNA [NM_009752] KLA1.300 1.220 1.300 1.220 0.950 1.030 1.360
Compactin1.330 1.190 1.310 1.170 1.280 1.160 1.020
KLA/Compactin1.330 1.050 1.190 1.240 0.980 1.040 1.150
Gns
KLA  Compactin  Compactin+KLA
 AK040524 0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430105C13 product:glucosamine (N-acetyl)-6-sulfatase, full insert sequence. [AK040524] KLA0.820 0.760 0.820 1.020 1.050 1.000 0.940
Compactin0.940 1.020 0.860 0.830 0.990 0.940 0.910
KLA/Compactin0.740 0.830 0.810 0.930 0.980 0.940 1.040
Gns
KLA  Compactin  Compactin+KLA
 AK040524 0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430105C13 product:glucosamine (N-acetyl)-6-sulfatase, full insert sequence. [AK040524] KLA0.860 0.810 0.810 0.860 0.990 1.050 1.040
Compactin0.980 1.020 0.930 0.900 0.920 0.930 0.940
KLA/Compactin0.870 0.710 0.770 0.920 0.970 0.870 1.050
Gns
KLA  Compactin  Compactin+KLA
 NM_029364 glucosamine (N-acetyl)-6-sulfatase (Gns), mRNA [NM_029364] KLA0.910 0.890 0.800 0.800 1.210 1.170 1.550
Compactin0.910 0.840 0.930 0.860 0.810 0.820 0.650
KLA/Compactin0.930 0.840 0.970 0.690 0.850 1.090 1.510
Gns
KLA  Compactin  Compactin+KLA
 NM_029364 glucosamine (N-acetyl)-6-sulfatase (Gns), mRNA [NM_029364] KLA1.020 0.880 1.060 0.850 1.140 1.190 1.860
Compactin1.040 1.010 0.970 1.090 0.850 0.810 0.680
KLA/Compactin1.110 0.940 1.020 0.790 0.990 1.140 1.630
Gns
KLA  Compactin  Compactin+KLA
 NM_029364 glucosamine (N-acetyl)-6-sulfatase (Gns), mRNA [NM_029364] KLA1.020 0.930 0.960 0.750 0.830 1.060 0.880
Compactin1.090 1.130 1.040 1.160 1.010 0.780 0.510
KLA/Compactin1.130 1.030 0.890 0.640 0.820 1.080 0.600
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA0.790 0.900 0.660 0.730 0.970 0.780 0.720
Compactin0.960 0.970 0.890 0.740 0.820 0.930 0.680
KLA/Compactin1.060 1.020 0.810 0.600 0.550 0.570 0.720
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA0.800 0.870 0.650 0.780 0.890 0.730 0.690
Compactin0.870 0.870 0.850 0.770 0.790 1.010 0.690
KLA/Compactin0.970 0.980 0.900 0.680 0.530 0.560 0.710
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA0.850 0.760 0.780 0.650 0.760 0.740 0.860
Compactin0.910 0.950 0.710 0.680 0.840 0.800 0.650
KLA/Compactin0.900 1.020 0.820 0.610 0.490 0.830 0.640
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA0.860 0.830 0.890 0.750 0.660 0.930 1.020
Compactin0.920 0.970 0.850 0.940 0.810 0.820 0.750
KLA/Compactin0.990 0.920 0.960 0.610 0.660 0.800 0.590
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA0.900 0.860 0.910 0.700 0.550 0.900 1.030
Compactin1.080 0.860 0.940 1.020 0.910 0.820 0.730
KLA/Compactin1.000 0.930 0.770 0.780 0.690 0.730 0.630
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA0.900 0.870 0.930 0.780 0.850 0.960 0.930
Compactin0.890 0.960 0.930 0.780 0.760 0.870 0.770
KLA/Compactin0.990 0.900 0.840 0.800 0.570 0.680 0.680
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA0.910 0.900 0.940 0.710 0.900 0.930 0.970
Compactin0.840 0.810 1.000 0.780 0.800 0.850 0.750
KLA/Compactin1.010 0.860 0.910 0.660 0.550 0.690 0.680
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA0.980 1.010 1.040 0.810 0.850 1.020 1.040
Compactin1.100 1.060 1.250 1.010 0.890 0.840 0.810
KLA/Compactin1.190 0.960 0.950 0.840 0.730 0.750 0.690
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA1.080 1.010 0.990 0.900 0.710 0.890 1.090
Compactin1.210 1.030 1.120 1.140 1.100 0.840 0.740
KLA/Compactin1.240 1.010 1.060 0.810 0.620 0.800 0.650
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA1.120 0.940 0.990 0.750 0.780 0.910 0.960
Compactin0.950 1.060 1.010 0.880 0.860 0.860 0.740
KLA/Compactin1.180 0.970 1.250 0.760 0.550 0.830 0.740
Gusb
KLA  Compactin  Compactin+KLA
 NM_010368 glucuronidase, beta (Gusb), mRNA [NM_010368] KLA1.140 1.030 0.810 0.900 0.770 1.070 0.980
Compactin0.910 1.090 1.280 0.980 0.850 0.860 0.750
KLA/Compactin1.230 1.020 1.020 0.790 0.580 0.830 0.650
Hexa
KLA  Compactin  Compactin+KLA
 NM_010421 hexosaminidase A (Hexa), mRNA [NM_010421] KLA1.110 0.990 0.970 0.990 0.880 0.850 0.780
Compactin1.180 1.110 1.120 1.170 0.940 0.890 0.700
KLA/Compactin1.180 1.030 0.950 0.980 0.740 0.730 0.680
Hexb
KLA  Compactin  Compactin+KLA
 NM_010422 hexosaminidase B (Hexb), mRNA [NM_010422] KLA1.110 1.030 1.020 0.940 0.600 0.580 0.730
Compactin1.150 1.100 1.100 1.130 1.100 1.040 0.950
KLA/Compactin1.270 1.070 0.920 0.930 0.670 0.590 0.610
Hgsnat
KLA  Compactin  Compactin+KLA
 NM_029884 heparan-alpha-glucosaminide N-acetyltransferase (Hgsnat), mRNA [NM_029884] KLA0.960 1.180 1.230 1.030 1.010 1.380 1.660
Compactin1.090 1.030 1.050 1.090 0.990 1.270 1.800
KLA/Compactin1.040 1.250 1.110 1.000 1.050 1.840 2.340
Hpse
KLA  Compactin  Compactin+KLA
 NM_152803 heparanase (Hpse), mRNA [NM_152803] KLA0.960 0.970 0.970 1.060 0.990 0.880 0.750
Compactin0.990 1.010 0.990 0.990 0.960 0.960 0.770
KLA/Compactin0.950 0.980 0.980 1.030 1.050 1.090 0.840
Hyal1
KLA  Compactin  Compactin+KLA
 145966880 hyaluronoglucosaminidase 1 KLA0.730 0.480 0.400 0.380 0.560 0.500 0.510
Compactin0.970 1.010 0.930 0.830 0.950 0.630 0.530
KLA/Compactin0.880 0.460 0.380 0.430 0.400 0.430 0.480
Hyal1
KLA  Compactin  Compactin+KLA
 NM_008317 hyaluronoglucosaminidase 1 (Hyal1), mRNA [NM_008317] KLA0.750 0.540 0.380 0.460 0.670 0.510 0.430
Compactin0.910 1.030 0.840 0.720 1.080 0.810 0.520
KLA/Compactin0.780 0.560 0.410 0.460 0.480 0.510 0.550
Hyal2
KLA  Compactin  Compactin+KLA
 NM_010489 hyaluronoglucosaminidase 2 (Hyal2), mRNA [NM_010489] KLA0.860 0.760 0.770 0.790 0.940 0.820 0.660
Compactin0.880 0.830 0.900 0.760 0.910 0.910 0.950
KLA/Compactin0.900 0.850 0.700 0.700 0.760 0.760 0.810
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA0.980 0.930 1.000 0.920 0.910 0.900 1.160
Compactin1.030 1.070 1.020 1.050 1.030 0.940 0.910
KLA/Compactin0.970 0.990 1.070 0.880 0.910 0.870 1.140
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA0.980 0.970 0.990 1.000 0.940 0.890 1.030
Compactin1.020 1.090 1.030 1.000 0.950 0.950 0.920
KLA/Compactin1.000 0.950 0.970 1.040 0.960 0.950 1.030
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA0.990 1.020 0.960 1.040 0.930 0.910 1.150
Compactin1.080 1.000 1.040 0.930 0.920 0.950 0.890
KLA/Compactin0.990 1.020 1.030 0.990 0.960 0.900 1.110
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA0.990 1.100 0.940 0.940 1.240 0.870 1.030
Compactin0.930 0.990 1.010 0.910 0.870 0.920 0.920
KLA/Compactin0.970 0.970 0.960 0.940 0.940 0.900 1.110
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA1.000 1.110 0.930 0.980 0.960 0.840 1.130
Compactin1.110 0.990 1.040 1.040 1.000 0.980 0.900
KLA/Compactin1.090 1.010 1.040 0.960 1.050 0.940 1.170
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA1.010 1.040 1.020 0.980 0.990 0.890 1.130
Compactin1.030 1.000 0.970 1.010 1.050 0.950 0.950
KLA/Compactin1.020 1.080 1.020 0.940 0.970 0.890 1.050
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA1.020 1.000 1.030 0.970 0.960 0.880 1.140
Compactin1.070 1.020 0.950 0.890 1.050 0.930 0.940
KLA/Compactin1.000 1.010 0.980 0.940 0.970 0.890 1.080
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA1.050 0.960 1.000 0.980 0.980 1.010 0.950
Compactin1.060 0.900 0.950 0.990 1.040 1.020 0.950
KLA/Compactin0.970 0.890 1.020 0.990 0.990 0.960 0.960
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA1.050 1.010 0.970 1.090 0.950 0.890 1.090
Compactin1.010 1.030 1.000 0.940 1.060 0.900 0.910
KLA/Compactin1.090 1.020 1.070 0.950 0.940 0.910 1.170
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA1.050 1.010 0.990 0.980 0.980 0.940 1.080
Compactin0.970 1.020 1.040 1.010 1.010 0.970 0.850
KLA/Compactin0.980 0.990 1.070 1.030 0.930 0.880 1.110
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA1.060 0.970 1.000 0.980 0.980 0.950 1.130
Compactin0.980 0.970 0.960 0.980 0.960 0.930 1.010
KLA/Compactin0.990 0.970 1.000 1.000 0.990 0.910 1.080
Hyal3
KLA  Compactin  Compactin+KLA
 NM_178020 hyaluronoglucosaminidase 3 (Hyal3), mRNA [NM_178020] KLA1.060 0.990 0.950 1.040 1.020 0.910 1.050
Compactin1.040 1.020 1.000 0.970 0.970 1.010 0.970
KLA/Compactin0.970 1.020 1.000 0.930 0.910 0.890 1.150
Hyal4
KLA  Compactin  Compactin+KLA
 AK014599 0 day neonate skin cDNA, RIKEN full-length enriched library, clone:4632428M18 product:similar to HYALURONIDASE 4 [Homo sapiens], full insert sequence [AK014599] KLA1.080 0.950 0.930 1.030 0.950 0.900 0.880
Compactin0.960 1.010 0.950 1.010 0.960 1.000 1.000
KLA/Compactin1.020 1.020 0.990 0.980 1.040 0.940 1.030
Hyal5
KLA  Compactin  Compactin+KLA
 NM_028957 hyaluronoglucosaminidase 5 (Hyal5), mRNA [NM_028957] KLA0.990 0.960 0.970 1.000 1.050 1.030 1.010
Compactin0.950 0.990 1.010 0.990 0.980 0.950 1.030
KLA/Compactin0.940 0.600 0.930 1.020 0.990 1.050 1.030
Hyal6
KLA  Compactin  Compactin+KLA
 NM_028920 hyaluronoglucosaminidase 6 (Hyal6), mRNA [NM_028920] KLA0.970 1.000 0.980 0.950 0.970 1.070 1.040
Compactin0.940 0.990 1.010 0.990 0.970 1.010 1.030
KLA/Compactin0.980 1.030 0.960 0.980 0.980 1.000 1.020
Ids
KLA  Compactin  Compactin+KLA
 NM_010498 iduronate 2-sulfatase (Ids), transcript variant 1, mRNA [NM_010498] KLA0.930 0.960 1.010 1.000 1.000 1.040 1.010
Compactin0.990 0.940 1.010 1.080 1.150 1.050 0.970
KLA/Compactin1.040 0.990 0.950 0.990 1.120 1.100 1.170
Ids
KLA  Compactin  Compactin+KLA
 NM_010498 iduronate 2-sulfatase (Ids), transcript variant 1, mRNA [NM_010498] KLA0.930 1.000 0.970 0.930 0.940 1.070 0.960
Compactin0.950 0.980 0.960 1.090 0.960 0.960 0.990
KLA/Compactin1.000 0.960 1.010 1.020 1.050 1.310 1.100
Ids
KLA  Compactin  Compactin+KLA
 NM_010498 iduronate 2-sulfatase (Ids), transcript variant 1, mRNA [NM_010498] KLA0.980 0.980 0.780 1.040 0.930 1.050 0.650
Compactin0.890 1.000 0.930 1.000 1.110 1.140 1.130
KLA/Compactin0.930 0.860 0.880 1.070 1.320 1.530 0.980
Ids
KLA  Compactin  Compactin+KLA
 NM_010498 iduronate 2-sulfatase (Ids), transcript variant 1, mRNA [NM_010498] KLA0.990 1.050 1.000 1.090 1.080 1.010 0.990
Compactin1.030 1.060 1.070 1.140 0.930 1.000 1.030
KLA/Compactin0.940 1.010 1.020 1.090 1.040 1.090 1.120
Idua
KLA  Compactin  Compactin+KLA
 NM_008325 iduronidase, alpha-L- (Idua), mRNA [NM_008325] KLA1.020 0.950 0.940 0.860 0.940 0.950 1.300
Compactin1.050 1.080 1.070 0.980 1.010 0.880 0.910
KLA/Compactin1.090 1.030 0.990 1.080 0.880 1.140 1.220
Naglu
KLA  Compactin  Compactin+KLA
 AK158045 adult inner ear cDNA, RIKEN full-length enriched library, clone:F930021C23 product:alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB), full insert sequence [AK158045] KLA0.930 1.030 1.140 0.920 0.940 1.020 0.960
Compactin0.880 0.970 0.990 0.970 0.940 1.010 1.020
KLA/Compactin0.940 0.970 0.950 1.080 0.990 0.980 1.080
Naglu
KLA  Compactin  Compactin+KLA
 NM_013792 alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) (Naglu), mRNA [NM_013792] KLA1.100 0.990 1.050 0.870 0.760 1.010 1.330
Compactin1.170 1.170 1.110 1.250 1.040 0.980 0.870
KLA/Compactin1.240 1.120 0.990 0.950 0.770 1.200 1.110
Sgsh
KLA  Compactin  Compactin+KLA
 NM_018822 N-sulfoglucosamine sulfohydrolase (sulfamidase) (Sgsh), mRNA [NM_018822] KLA0.950 0.920 0.910 0.940 0.840 0.920 0.800
Compactin1.050 1.010 0.990 1.000 0.990 0.950 0.950
KLA/Compactin1.050 0.980 1.000 0.920 0.870 0.940 0.790
Sgsh
KLA  Compactin  Compactin+KLA
 NM_018822 N-sulfoglucosamine sulfohydrolase (sulfamidase) (Sgsh), mRNA [NM_018822] KLA0.970 1.050 0.990 0.890 0.830 0.910 0.820
Compactin1.050 1.010 1.100 1.020 0.950 1.060 0.920
KLA/Compactin1.030 1.070 0.950 0.880 0.900 0.880 0.810
Sgsh
KLA  Compactin  Compactin+KLA
 NM_018822 N-sulfoglucosamine sulfohydrolase (sulfamidase) (Sgsh), mRNA [NM_018822] KLA1.050 0.840 0.600 0.230 0.320 0.410 0.250
Compactin1.060 1.120 1.090 1.130 0.970 0.910 0.680
KLA/Compactin1.120 0.890 0.670 0.320 0.300 0.330 0.230
Spam1
KLA  Compactin  Compactin+KLA
 NM_001079875 sperm adhesion molecule 1 (Spam1), transcript variant 1, mRNA [NM_001079875] KLA1.000 1.000 1.020 1.000 0.970 0.970 1.040
Compactin0.970 1.020 1.040 1.070 0.960 0.980 1.040
KLA/Compactin1.010 1.030 0.980 0.970 0.990 0.960 0.960