Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Butirosin and neomycin biosynthesis (mmu00524)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Gck
KLA  Compactin  Compactin+KLA
 NM_010292 glucokinase (Gck), mRNA [NM_010292] KLA1.000 0.990 1.040 0.930 1.030 1.070 1.020
Compactin0.950 1.000 1.010 0.990 0.950 1.030 1.090
KLA/Compactin0.980 0.960 1.040 0.990 1.040 0.760 0.860
Gck
KLA  Compactin  Compactin+KLA
 NM_010292 glucokinase (Gck), mRNA [NM_010292] KLA1.050 0.930 1.000 1.000 0.970 1.110 1.040
Compactin0.970 0.950 0.980 1.010 1.010 0.980 0.960
KLA/Compactin0.940 1.000 0.990 1.000 0.950 0.960 1.010
Hk1
KLA  Compactin  Compactin+KLA
 J05277 gb|Mouse hexokinase mRNA, complete cds [J05277] KLA0.850 0.880 0.770 0.870 1.990 1.830 2.040
Compactin0.920 0.970 0.860 0.820 1.130 1.400 1.340
KLA/Compactin1.000 0.900 0.890 0.810 1.600 2.030 2.620
Hk1
KLA  Compactin  Compactin+KLA
 NM_010438 hexokinase 1 (Hk1), nuclear gene encoding mitochondrial protein, mRNA [NM_010438] KLA0.860 0.920 0.830 0.960 1.680 1.580 2.270
Compactin0.960 0.910 0.870 0.810 1.150 1.320 1.310
KLA/Compactin0.930 0.880 0.830 0.880 1.560 2.000 3.120
Hk1
KLA  Compactin  Compactin+KLA
 NM_010438 hexokinase 1 (Hk1), nuclear gene encoding mitochondrial protein, mRNA [NM_010438] KLA0.980 1.040 0.990 1.050 1.070 1.040 1.060
Compactin1.100 0.980 1.060 1.060 1.050 1.080 1.050
KLA/Compactin0.980 1.030 1.000 0.980 1.040 1.210 1.110
Hk1
KLA  Compactin  Compactin+KLA
 NM_010438 hexokinase 1 (Hk1), nuclear gene encoding mitochondrial protein, mRNA [NM_010438] KLA1.000 0.950 0.930 0.950 1.470 1.620 1.990
Compactin1.020 0.920 0.940 1.040 1.040 1.240 1.160
KLA/Compactin1.000 0.970 0.970 0.980 1.650 1.880 2.220
Hk1
KLA  Compactin  Compactin+KLA
 NM_010438 hexokinase 1 (Hk1), nuclear gene encoding mitochondrial protein, mRNA [NM_010438] KLA1.010 1.010 1.030 1.030 1.610 1.610 2.370
Compactin1.000 0.990 1.030 1.090 1.120 1.320 1.390
KLA/Compactin1.030 1.070 0.980 1.040 1.570 2.210 2.730
Hk2
KLA  Compactin  Compactin+KLA
 NM_013820 hexokinase 2 (Hk2), mRNA [NM_013820] KLA1.080 1.150 1.110 1.620 1.550 1.530 1.480
Compactin0.880 0.980 0.930 0.980 1.020 1.150 1.050
KLA/Compactin1.050 1.250 1.000 1.710 1.500 1.530 1.430
Hk3
KLA  Compactin  Compactin+KLA
 NM_001033245 hexokinase 3 (Hk3), nuclear gene encoding mitochondrial protein, mRNA [NM_001033245] KLA1.110 1.060 0.940 1.510 2.390 3.090 2.140
Compactin1.070 1.160 1.090 1.160 0.880 0.870 1.230
KLA/Compactin1.170 1.060 0.890 1.210 2.010 2.560 1.710
Hkdc1
KLA  Compactin  Compactin+KLA
 NM_145419 hexokinase domain containing 1 (Hkdc1), mRNA [NM_145419] KLA0.970 1.020 1.010 1.000 1.020 0.960 1.080
Compactin1.030 0.960 0.890 1.060 1.010 0.960 0.950
KLA/Compactin1.090 1.000 0.940 0.960 0.970 1.040 0.980