Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Cyanoamino acid metabolism (mmu00460)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Ggt1
KLA  Compactin  Compactin+KLA
 NM_008116 gamma-glutamyltransferase 1 (Ggt1), mRNA [NM_008116] KLA0.970 0.980 0.940 0.950 1.000 1.030 1.030
Compactin1.000 1.010 0.960 0.950 1.020 0.990 0.970
KLA/Compactin1.060 0.940 1.080 1.120 0.990 1.010 1.000
Ggt1
KLA  Compactin  Compactin+KLA
 NM_008116 gamma-glutamyltransferase 1 (Ggt1), mRNA [NM_008116] KLA0.990 1.070 1.020 0.980 1.030 0.980 0.980
Compactin0.990 1.000 0.970 0.950 0.960 0.990 1.000
KLA/Compactin0.950 1.020 0.940 1.010 0.980 1.030 1.000
Ggt5
KLA  Compactin  Compactin+KLA
 NM_011820 gamma-glutamyltransferase 5 (Ggt5), mRNA [NM_011820] KLA1.040 1.000 1.010 0.980 0.990 0.990 1.000
Compactin1.110 1.100 0.960 1.030 1.550 0.980 0.960
KLA/Compactin0.930 1.010 1.040 0.960 0.980 1.050 0.960
Ggt5
KLA  Compactin  Compactin+KLA
 NM_011820 gamma-glutamyltransferase 5 (Ggt5), mRNA [NM_011820] KLA1.060 1.040 0.950 0.990 1.000 0.970 1.000
Compactin1.020 0.980 0.970 1.020 0.980 1.060 0.960
KLA/Compactin0.910 0.930 1.050 1.050 0.960 0.990 0.970
Ggt6
KLA  Compactin  Compactin+KLA
 NM_027819 gamma-glutamyltransferase 6 (Ggt6), mRNA [NM_027819] KLA1.110 1.000 1.000 1.010 0.960 0.970 0.940
Compactin0.980 1.030 0.980 0.980 0.960 1.040 1.000
KLA/Compactin1.040 1.000 0.970 1.000 0.940 0.950 0.960
Ggt7
KLA  Compactin  Compactin+KLA
 NM_144786 gamma-glutamyltransferase 7 (Ggt7), mRNA [NM_144786] KLA1.000 1.020 1.030 1.060 0.960 1.000 1.040
Compactin0.950 1.010 0.930 0.970 1.010 1.040 0.940
KLA/Compactin1.010 0.980 0.990 1.030 0.980 1.070 1.010
Ggt7
KLA  Compactin  Compactin+KLA
 NM_144786 gamma-glutamyltransferase 7 (Ggt7), mRNA [NM_144786] KLA1.010 0.980 0.930 1.000 0.990 1.040 1.130
Compactin1.110 1.040 1.050 0.960 1.050 1.020 0.980
KLA/Compactin0.960 0.960 1.000 1.020 1.020 1.000 1.090
Shmt1
KLA  Compactin  Compactin+KLA
 NM_009171 serine hydroxymethyltransferase 1 (soluble) (Shmt1), mRNA [NM_009171] KLA0.870 1.060 0.980 0.760 0.850 0.700 0.740
Compactin1.130 0.900 0.960 0.870 0.850 1.120 0.770
KLA/Compactin0.780 1.050 0.850 0.830 0.560 0.610 0.870
Shmt1
KLA  Compactin  Compactin+KLA
 NM_009171 serine hydroxymethyltransferase 1 (soluble) (Shmt1), mRNA [NM_009171] KLA0.990 0.970 1.060 0.850 0.520 0.540 0.430
Compactin1.020 1.030 1.020 1.010 0.940 0.950 0.690
KLA/Compactin0.910 1.120 0.910 0.680 0.480 0.410 0.430
Shmt1
KLA  Compactin  Compactin+KLA
 NM_009171 serine hydroxymethyltransferase 1 (soluble) (Shmt1), mRNA [NM_009171] KLA1.140 1.210 1.160 0.930 0.780 0.800 0.720
Compactin1.150 1.090 1.100 1.120 0.960 0.980 0.840
KLA/Compactin1.110 1.220 1.230 1.010 0.700 0.580 0.810
Shmt2
KLA  Compactin  Compactin+KLA
 NM_028230 serine hydroxymethyltransferase 2 (mitochondrial) (Shmt2), nuclear gene encoding mitochondrial protein, mRNA [NM_028230] KLA1.030 1.060 0.880 0.810 0.840 0.990 0.910
Compactin1.070 1.050 1.140 1.090 1.070 0.950 1.020
KLA/Compactin1.070 1.050 1.090 0.860 0.780 1.010 0.690