Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Histidine metabolism (mmu00340)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
1700055N
04Rik
KLA  Compactin  Compactin+KLA
 94405716 RIKEN cDNA 1700055N04 gene KLA0.910 0.920 1.020 1.030 0.920 0.840 1.020
Compactin1.040 1.010 0.940 0.990 0.910 1.010 0.910
KLA/Compactin0.940 1.020 1.010 1.020 0.940 1.030 1.080
1700055N
04Rik
KLA  Compactin  Compactin+KLA
 AK081788 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130077J09 product:weakly similar to ALDEHYDE DEHYDROGENASE 7 (EC 1.2.1.5) [Homo sapiens], full insert sequence [AK081788] KLA0.980 0.950 0.940 0.960 0.990 1.020 1.030
Compactin1.050 0.970 0.970 1.020 1.050 1.010 0.880
KLA/Compactin1.000 1.010 0.970 1.010 1.020 0.980 1.000
Abp1
KLA  Compactin  Compactin+KLA
 NM_029638 amiloride binding protein 1 (amine oxidase, copper-containing) (Abp1), mRNA [NM_029638] KLA0.990 0.990 1.010 1.040 1.010 0.930 0.930
Compactin1.050 0.990 0.990 1.050 0.980 0.980 0.990
KLA/Compactin1.030 1.000 0.930 0.970 0.950 0.950 1.010
Acy3
KLA  Compactin  Compactin+KLA
 NM_027857 aspartoacylase (aminoacylase) 3 (Acy3), mRNA [NM_027857] KLA1.040 0.940 1.030 1.030 0.910 0.970 1.150
Compactin0.950 1.050 0.970 0.950 0.870 0.960 1.030
KLA/Compactin0.960 0.960 0.980 0.970 0.940 1.080 1.240
AI790298
KLA  Compactin  Compactin+KLA
 AK129347 mRNA for mKIAA1394 protein [AK129347] KLA1.010 0.990 0.990 1.040 1.010 1.070 1.020
Compactin1.030 1.010 0.960 1.030 0.970 0.980 1.010
KLA/Compactin0.940 1.010 1.050 1.020 1.000 0.950 0.930
Aldh1a3
KLA  Compactin  Compactin+KLA
 AK086764 15 days embryo head cDNA, RIKEN full-length enriched library, clone:D930050B08 product:aldehyde dehydrogenase family 1, subfamily A3, full insert sequence. [AK086764] KLA1.000 1.030 0.980 1.000 1.020 1.060 0.940
Compactin1.020 1.020 1.060 1.050 1.010 0.980 1.040
KLA/Compactin0.990 1.270 0.990 1.080 1.020 0.970 1.030
Aldh1a3
KLA  Compactin  Compactin+KLA
 NM_053080 aldehyde dehydrogenase family 1, subfamily A3 (Aldh1a3), mRNA [NM_053080] KLA1.010 1.070 1.000 0.950 1.090 1.020 1.050
Compactin0.910 1.000 1.050 0.970 0.920 1.020 1.020
KLA/Compactin0.980 0.940 1.020 1.000 0.970 0.930 1.040
Aldh1b1
KLA  Compactin  Compactin+KLA
 NM_028270 aldehyde dehydrogenase 1 family, member B1 (Aldh1b1), nuclear gene encoding mitochondrial protein, mRNA [NM_028270] KLA0.990 0.930 1.090 2.540 4.350 5.420 5.340
Compactin1.030 0.980 1.040 1.190 0.880 0.810 1.090
KLA/Compactin0.970 0.900 1.030 2.940 5.190 6.900 5.710
Aldh2
KLA  Compactin  Compactin+KLA
 AK163452 adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230105J09 product:aldehyde dehydrogenase 2, mitochondrial, full insert sequence [AK163452] KLA0.980 1.050 1.010 0.980 1.000 1.030 1.060
Compactin1.050 1.010 1.010 1.030 1.070 1.030 0.970
KLA/Compactin0.990 1.000 1.030 0.950 1.030 0.960 1.050
Aldh2
KLA  Compactin  Compactin+KLA
 NM_009656 aldehyde dehydrogenase 2, mitochondrial (Aldh2), nuclear gene encoding mitochondrial protein, mRNA [NM_009656] KLA0.940 0.930 0.960 0.980 0.830 0.900 0.880
Compactin1.080 0.910 0.930 1.150 1.580 1.000 0.840
KLA/Compactin1.050 1.030 1.050 0.790 1.020 0.880 0.860
Aldh3a1
KLA  Compactin  Compactin+KLA
 NM_007436 aldehyde dehydrogenase family 3, subfamily A1 (Aldh3a1), transcript variant 1, mRNA [NM_007436] KLA1.010 1.050 1.100 0.970 0.990 1.000 0.960
Compactin0.980 1.010 1.010 0.980 1.050 0.970 1.040
KLA/Compactin1.000 1.000 0.960 1.070 1.020 1.020 1.040
Aldh3a2
KLA  Compactin  Compactin+KLA
 NM_007437 aldehyde dehydrogenase family 3, subfamily A2 (Aldh3a2), mRNA [NM_007437] KLA1.040 0.900 0.840 0.840 1.130 1.330 1.150
Compactin1.020 1.070 0.990 1.170 1.000 0.960 1.110
KLA/Compactin1.110 0.870 0.880 0.930 1.320 1.440 1.120
Aldh3b1
KLA  Compactin  Compactin+KLA
 NM_026316 aldehyde dehydrogenase 3 family, member B1 (Aldh3b1), mRNA [NM_026316] KLA0.990 1.030 1.100 1.000 0.840 1.250 1.060
Compactin1.120 1.100 1.310 1.250 0.960 1.020 0.850
KLA/Compactin1.170 1.050 1.070 1.040 0.980 1.140 0.940
Aldh3b2
KLA  Compactin  Compactin+KLA
 94405693 aldehyde dehydrogenase 3 family, member B2 KLA1.010 1.010 0.960 0.970 0.940 1.030 0.980
Compactin1.050 1.080 0.980 1.010 1.150 0.980 1.020
KLA/Compactin0.980 0.950 1.000 1.020 0.980 1.000 1.050
Aldh3b2
KLA  Compactin  Compactin+KLA
 XM_129134 gb|PREDICTED: Mus musculus aldehyde dehydrogenase 3 family, member B2 (Aldh3b2), mRNA [XM_129134] KLA0.900 0.870 0.920 0.990 1.040 1.080 1.040
Compactin0.860 0.950 0.900 0.930 0.920 0.950 0.850
KLA/Compactin0.940 0.880 0.890 1.040 0.880 1.010 1.150
Aldh7a1
KLA  Compactin  Compactin+KLA
 NM_138600 aldehyde dehydrogenase family 7, member A1 (Aldh7a1), mRNA [NM_138600] KLA0.970 0.980 0.980 1.060 1.020 1.080 1.220
Compactin1.000 1.070 0.990 1.010 0.950 0.980 0.990
KLA/Compactin1.000 1.020 1.010 1.150 1.070 1.060 1.260
Aldh7a1
KLA  Compactin  Compactin+KLA
 NM_138600 aldehyde dehydrogenase family 7, member A1 (Aldh7a1), mRNA [NM_138600] KLA1.000 0.990 1.000 1.070 1.060 1.000 1.010
Compactin0.990 0.950 1.010 0.990 0.970 0.950 1.000
KLA/Compactin1.060 1.010 0.990 0.990 0.920 1.020 0.960
Aldh9a1
KLA  Compactin  Compactin+KLA
 NM_019993 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA [NM_019993] KLA0.900 0.880 0.920 0.850 0.780 0.700 0.750
Compactin0.890 0.960 0.920 0.920 1.080 1.090 0.980
KLA/Compactin0.840 0.950 0.950 0.850 0.750 0.710 0.870
Aldh9a1
KLA  Compactin  Compactin+KLA
 NM_019993 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA [NM_019993] KLA0.930 0.840 0.770 0.830 0.740 0.590 0.640
Compactin0.870 0.870 0.910 0.930 0.990 0.980 0.980
KLA/Compactin0.890 0.960 0.890 0.710 0.660 0.600 0.630
Aldh9a1
KLA  Compactin  Compactin+KLA
 NM_019993 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA [NM_019993] KLA1.020 0.950 0.990 0.900 0.680 0.660 0.630
Compactin1.180 1.040 1.120 1.230 1.070 1.030 0.960
KLA/Compactin1.110 0.940 1.000 0.880 0.670 0.650 0.700
Amdhd1
KLA  Compactin  Compactin+KLA
 XM_125854 gb|PREDICTED: Mus musculus amidohydrolase domain containing 1 (Amdhd1), mRNA [XM_125854] KLA0.990 0.980 1.020 0.980 1.040 0.990 1.030
Compactin0.990 1.030 0.940 1.430 1.080 1.040 0.950
KLA/Compactin0.990 0.990 0.930 0.980 1.050 0.940 0.970
Amdhd1
KLA  Compactin  Compactin+KLA
 XM_125854 gb|PREDICTED: Mus musculus amidohydrolase domain containing 1 (Amdhd1), mRNA [XM_125854] KLA1.010 1.060 1.020 1.060 1.110 1.050 0.970
Compactin0.920 1.010 1.020 1.030 0.920 1.030 1.010
KLA/Compactin1.010 0.990 0.980 1.010 0.990 1.020 1.040
Aspa
KLA  Compactin  Compactin+KLA
 NM_023113 aspartoacylase (Aspa), mRNA [NM_023113] KLA1.040 0.980 1.070 1.050 0.980 0.930 0.990
Compactin1.050 0.970 0.970 1.020 1.060 1.020 1.030
KLA/Compactin1.070 0.980 1.020 0.980 1.000 0.990 0.950
Aspa
KLA  Compactin  Compactin+KLA
 NM_023113 aspartoacylase (Aspa), mRNA [NM_023113] KLA1.100 0.940 1.060 1.190 1.190 1.270 1.170
Compactin1.030 0.880 1.070 1.020 1.020 1.090 0.990
KLA/Compactin1.070 0.920 1.010 1.090 1.280 1.150 1.120
Cndp1
KLA  Compactin  Compactin+KLA
 NM_177450 carnosine dipeptidase 1 (metallopeptidase M20 family) (Cndp1), mRNA [NM_177450] KLA1.040 0.990 0.970 0.990 1.020 1.000 0.970
Compactin1.030 1.020 1.050 1.060 1.000 1.020 0.920
KLA/Compactin1.000 0.980 0.960 0.950 1.050 1.050 0.950
Cndp2
KLA  Compactin  Compactin+KLA
 NM_023149 CNDP dipeptidase 2 (metallopeptidase M20 family) (Cndp2), mRNA [NM_023149] KLA1.220 1.120 1.350 1.810 3.020 3.910 3.700
Compactin1.140 1.120 1.160 1.120 1.050 1.070 1.230
KLA/Compactin1.130 1.050 1.270 1.740 3.210 2.930 3.450
Ddc
KLA  Compactin  Compactin+KLA
 NM_016672 dopa decarboxylase (Ddc), mRNA [NM_016672] KLA1.070 0.970 0.960 1.000 1.050 0.990 0.990
Compactin0.960 0.980 1.000 0.940 1.060 1.000 0.960
KLA/Compactin0.990 1.030 0.970 1.050 0.930 0.960 0.990
Ddc
KLA  Compactin  Compactin+KLA
 NM_016672 dopa decarboxylase (Ddc), mRNA [NM_016672] KLA1.090 1.020 0.920 0.990 1.040 0.940 1.020
Compactin1.030 1.030 1.060 0.950 1.000 1.040 0.990
KLA/Compactin0.940 0.930 0.990 0.960 0.960 1.090 0.980
Ftcd
KLA  Compactin  Compactin+KLA
 NM_080845 formiminotransferase cyclodeaminase (Ftcd), mRNA [NM_080845] KLA1.070 1.020 0.990 1.030 0.930 0.960 0.940
Compactin1.050 0.950 1.020 0.960 1.050 1.040 0.990
KLA/Compactin0.980 1.030 1.030 0.990 0.910 1.060 0.940
Hal
KLA  Compactin  Compactin+KLA
 NM_010401 histidine ammonia lyase (Hal), mRNA [NM_010401] KLA0.980 0.980 0.910 0.820 0.760 0.550 0.330
Compactin0.970 1.000 0.930 0.980 0.930 0.860 1.470
KLA/Compactin0.980 0.960 0.840 0.810 0.730 0.510 0.290
Hdc
KLA  Compactin  Compactin+KLA
 NM_008230 histidine decarboxylase (Hdc), mRNA [NM_008230] KLA0.750 1.590 5.090 15.990 14.030 15.480 13.600
Compactin0.700 0.920 0.950 0.890 0.810 0.820 1.770
KLA/Compactin0.790 1.330 4.020 15.410 19.230 17.410 12.810
Hemk1
KLA  Compactin  Compactin+KLA
 NM_133984 HemK methyltransferase family member 1 (Hemk1), mRNA [NM_133984] KLA0.920 1.030 1.030 1.110 1.040 1.000 1.430
Compactin1.020 1.030 1.030 1.110 1.010 0.990 1.180
KLA/Compactin1.130 0.980 1.020 1.220 1.080 1.140 1.280
Hemk1
KLA  Compactin  Compactin+KLA
 NM_133984 HemK methyltransferase family member 1 (Hemk1), mRNA [NM_133984] KLA0.940 1.080 1.090 1.090 1.010 1.010 1.270
Compactin1.050 1.080 1.040 1.140 1.010 0.980 1.190
KLA/Compactin0.990 1.080 1.050 1.140 1.110 1.120 1.230
Hnmt
KLA  Compactin  Compactin+KLA
 NM_080462 histamine N-methyltransferase (Hnmt), mRNA [NM_080462] KLA1.030 0.960 1.000 1.070 1.080 0.960 0.970
Compactin1.040 0.970 1.050 1.030 1.020 0.990 0.900
KLA/Compactin0.990 1.060 0.940 0.980 0.980 0.970 1.060
Maoa
KLA  Compactin  Compactin+KLA
 NM_173740 monoamine oxidase A (Maoa), nuclear gene encoding mitochondrial protein, mRNA [NM_173740] KLA0.940 1.000 1.120 1.210 1.160 0.950 1.190
Compactin0.870 0.940 0.870 0.820 0.970 0.940 1.020
KLA/Compactin0.920 1.050 1.160 0.990 0.950 1.030 1.460
Maob
KLA  Compactin  Compactin+KLA
 NM_172778 monoamine oxidase B (Maob), nuclear gene encoding mitochondrial protein, mRNA [NM_172778] KLA1.000 0.950 0.970 0.940 0.970 1.010 1.030
Compactin0.930 1.020 0.970 1.020 0.930 1.030 1.060
KLA/Compactin0.970 0.900 1.040 1.070 0.980 0.980 1.030
Mettl2
KLA  Compactin  Compactin+KLA
 NM_172567 methyltransferase like 2 (Mettl2), mRNA [NM_172567] KLA0.950 1.200 1.350 1.340 1.000 0.880 0.660
Compactin1.080 1.070 1.030 1.120 0.990 0.950 0.950
KLA/Compactin1.080 1.230 1.240 1.150 0.940 0.840 0.570
Mettl6
KLA  Compactin  Compactin+KLA
 NM_025907 methyltransferase like 6 (Mettl6), mRNA [NM_025907] KLA0.930 1.060 1.130 1.220 2.220 1.990 2.280
Compactin0.890 0.940 0.850 0.870 1.090 1.040 0.890
KLA/Compactin0.950 1.100 1.070 1.240 1.890 2.550 2.300
Mettl6
KLA  Compactin  Compactin+KLA
 NM_025907 methyltransferase like 6 (Mettl6), mRNA [NM_025907] KLA0.950 1.180 1.420 1.610 2.120 2.100 2.310
Compactin0.860 1.020 1.060 1.170 0.990 0.930 1.030
KLA/Compactin0.940 1.090 1.260 1.600 2.300 2.480 2.120
Uroc1
KLA  Compactin  Compactin+KLA
 NM_144940 urocanase domain containing 1 (Uroc1), mRNA [NM_144940] KLA0.990 0.960 1.040 1.090 1.000 0.930 1.000
Compactin1.090 1.000 0.990 0.990 1.120 1.070 0.920
KLA/Compactin0.950 1.170 0.950 1.000 1.030 1.060 0.990
Wbscr22
KLA  Compactin  Compactin+KLA
 NM_025375 Williams Beuren syndrome chromosome region 22 (Wbscr22), mRNA [NM_025375] KLA1.020 0.930 0.830 1.020 1.220 0.990 0.940
Compactin0.980 1.100 0.930 0.860 0.980 1.180 1.110
KLA/Compactin0.860 0.960 1.120 0.910 0.890 0.890 1.240