Microarray analysis of RAW 264.7 cells treated with Kdo₂-lipid A (KLA) and compactin (full time course)

Kdo₂-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Fatty acid biosynthesis (mmu00061)

Legend: : View data/graphs for replicates

Gene symbol	Time course plot	Accession	Description	Treatment	30min	1hr	2hr	4hr	8hr	12hr	24hr
Acaca	KLA  Compactin  Compactin+KLA	NM_133360	acetyl-Coenzyme A carboxylase alpha (Acaca), mRNA [NM_133360]	KLA	0.930	1.050	1.000	1.010	0.940	0.990	0.990
				Compactin	1.050	1.020	1.010	1.030	1.060	0.980	0.980
				KLA/Compactin	1.050	1.070	0.940	1.010	0.970	0.990	0.980
Acaca	KLA  Compactin  Compactin+KLA	NM_133360	acetyl-Coenzyme A carboxylase alpha (Acaca), mRNA [NM_133360]	KLA	1.120	1.080	1.020	0.980	0.960	1.040	1.070
				Compactin	1.070	1.010	0.960	0.980	1.100	1.010	1.040
				KLA/Compactin	1.050	1.030	0.960	1.010	0.950	0.980	1.090
Acacb	KLA  Compactin  Compactin+KLA	NM_133904	acetyl-Coenzyme A carboxylase beta (Acacb), mRNA [NM_133904]	KLA	1.030	1.080	0.970	0.960	0.920	0.980	0.950
				Compactin	1.020	1.020	1.060	0.980	1.030	1.050	1.000
				KLA/Compactin	1.160	0.930	1.030	0.990	0.930	0.950	0.950
Fasn	KLA  Compactin  Compactin+KLA	NM_007988	fatty acid synthase (Fasn), mRNA [NM_007988]	KLA	1.060	1.270	1.190	0.650	0.580	0.350	0.150
				Compactin	0.990	1.000	1.010	0.880	0.980	1.020	0.670
				KLA/Compactin	1.100	1.060	1.140	0.640	0.400	0.300	0.110
Fasn	KLA  Compactin  Compactin+KLA	NM_007988	fatty acid synthase (Fasn), mRNA [NM_007988]	KLA	1.290	1.260	1.260	0.860	0.790	0.680	0.550
				Compactin	1.250	1.140	1.190	1.190	1.010	0.960	0.790
				KLA/Compactin	1.410	1.220	1.160	0.860	0.650	0.490	0.500
Mcat	KLA  Compactin  Compactin+KLA	NM_001030014	malonyl CoA:ACP acyltransferase (mitochondrial) (Mcat), nuclear gene encoding mitochondrial protein, mRNA [NM_001030014]	KLA	1.100	0.920	0.850	1.030	0.980	1.240	1.110
				Compactin	1.120	1.060	1.130	1.130	1.070	1.050	1.000
				KLA/Compactin	1.100	0.910	0.850	1.090	1.000	1.120	1.320
Olah	KLA  Compactin  Compactin+KLA	NM_145921	oleoyl-ACP hydrolase (Olah), mRNA [NM_145921]	KLA	0.950	1.400	0.940	0.880	1.470	1.040	0.950
				Compactin	0.900	1.010	1.020	0.990	0.920	0.990	1.080
				KLA/Compactin	0.970	0.890	1.020	0.980	0.980	0.910	1.080
Oxsm	KLA  Compactin  Compactin+KLA	NM_027695	3-oxoacyl-ACP synthase, mitochondrial (Oxsm), nuclear gene encoding mitochondrial protein, mRNA [NM_027695]	KLA	0.940	0.910	0.850	0.960	0.870	0.960	0.750
				Compactin	1.040	1.000	1.110	1.040	0.980	1.010	0.930
				KLA/Compactin	1.070	0.930	0.900	0.950	1.010	1.050	0.720
Oxsm	KLA  Compactin  Compactin+KLA	NM_027695	3-oxoacyl-ACP synthase, mitochondrial (Oxsm), nuclear gene encoding mitochondrial protein, mRNA [NM_027695]	KLA	1.010	0.970	0.840	0.860	0.840	0.800	0.630
				Compactin	0.930	1.050	0.970	0.950	1.010	0.850	0.950
				KLA/Compactin	1.010	0.920	0.840	0.870	0.980	0.800	0.590