Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Galactose metabolism (mmu00052)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
2010204N
08Rik
KLA  Compactin  Compactin+KLA
 124487274 RIKEN cDNA 2010204N08 gene KLA0.980 0.980 0.950 0.900 1.000 1.010 1.040
Compactin0.950 0.970 1.030 0.980 0.950 1.000 1.060
KLA/Compactin1.020 0.990 0.980 1.010 0.950 0.890 1.000
2010204N
08Rik
KLA  Compactin  Compactin+KLA
 NM_001081137 RIKEN cDNA 2010204N08 gene (2010204N08Rik), mRNA [NM_001081137] KLA1.030 0.890 0.980 0.960 1.020 0.960 0.950
Compactin0.980 0.910 1.160 0.970 1.020 1.010 1.040
KLA/Compactin0.980 0.970 0.980 0.950 0.970 0.910 0.980
2310005E
10Rik
KLA  Compactin  Compactin+KLA
 BC026843 RIKEN cDNA 2310005E10 gene, mRNA (cDNA clone IMAGE:4487182), complete cds. [BC026843] KLA0.820 0.450 0.680 0.730 0.840 0.940 0.840
Compactin0.910 1.060 0.980 0.870 1.030 0.930 0.970
KLA/Compactin0.800 0.460 0.670 0.680 0.730 0.700 0.820
2310005E
10Rik
KLA  Compactin  Compactin+KLA
 NM_172398 RIKEN cDNA 2310005E10 gene (2310005E10Rik), mRNA [NM_172398] KLA0.940 0.810 0.600 0.820 0.880 0.680 0.720
Compactin0.920 0.820 0.960 0.720 0.890 0.990 0.740
KLA/Compactin0.840 0.870 0.790 0.750 0.660 0.690 0.990
2310005E
10Rik
KLA  Compactin  Compactin+KLA
 NM_172398 RIKEN cDNA 2310005E10 gene (2310005E10Rik), mRNA [NM_172398] KLA1.000 0.880 0.990 0.960 0.690 0.880 0.960
Compactin1.020 1.020 1.080 0.970 1.040 0.870 0.830
KLA/Compactin1.040 0.930 0.770 0.870 0.840 0.970 1.020
AK209324
KLA  Compactin  Compactin+KLA
 AK209324 cDNA, clone:Y2G0114L23, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000060207, based on BLAT search. [AK209324] KLA0.880 0.650 1.030 0.930 1.150 0.940 0.680
Compactin1.180 1.090 1.030 0.970 1.050 0.980 0.980
KLA/Compactin0.950 0.650 0.990 0.860 1.040 0.700 0.560
Akr1b3
KLA  Compactin  Compactin+KLA
 AK054167 2 days pregnant adult female oviduct cDNA, RIKEN full-length enriched library, clone:E230024H01 product:unclassifiable, full insert sequence [AK054167] KLA0.990 0.960 1.020 0.990 1.030 0.990 1.030
Compactin1.000 0.980 0.980 1.000 1.020 0.980 0.960
KLA/Compactin0.980 0.980 1.000 0.990 1.030 0.950 1.030
Akr1b3
KLA  Compactin  Compactin+KLA
 NM_009658 aldo-keto reductase family 1, member B3 (aldose reductase) (Akr1b3), mRNA [NM_009658] KLA0.830 1.120 0.730 0.850 1.080 0.670 0.790
Compactin0.900 0.960 0.910 0.800 1.310 1.350 1.090
KLA/Compactin1.000 1.120 0.880 0.920 0.760 0.800 0.960
Akr1b3
KLA  Compactin  Compactin+KLA
 NM_009658 aldo-keto reductase family 1, member B3 (aldose reductase) (Akr1b3), mRNA [NM_009658] KLA0.990 0.950 0.930 0.990 0.750 0.750 0.680
Compactin1.040 0.980 1.130 1.210 0.900 1.180 1.080
KLA/Compactin0.990 0.920 0.910 0.950 0.840 0.990 0.750
Akr1b7
KLA  Compactin  Compactin+KLA
 NM_009731 aldo-keto reductase family 1, member B7 (Akr1b7), mRNA [NM_009731] KLA1.000 0.960 0.950 1.060 0.900 0.830 0.930
Compactin1.020 1.110 1.070 1.050 0.980 0.830 1.070
KLA/Compactin0.960 1.040 1.030 1.090 0.960 0.920 0.880
Akr1b8
KLA  Compactin  Compactin+KLA
 NM_008012 aldo-keto reductase family 1, member B8 (Akr1b8), mRNA [NM_008012] KLA1.180 0.850 1.070 0.900 0.930 1.560 3.590
Compactin1.200 0.990 1.130 1.180 1.200 1.300 1.960
KLA/Compactin1.150 0.970 1.110 0.900 1.160 2.390 3.670
B4galt1
KLA  Compactin  Compactin+KLA
 NM_022305 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (B4galt1), mRNA [NM_022305] KLA0.870 0.850 0.650 0.510 0.750 0.750 0.770
Compactin0.810 0.910 0.960 0.870 1.110 1.040 0.900
KLA/Compactin0.970 0.790 0.820 0.470 0.740 0.800 0.880
B4galt1
KLA  Compactin  Compactin+KLA
 NM_022305 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (B4galt1), mRNA [NM_022305] KLA0.890 0.790 0.820 0.480 0.930 0.680 0.920
Compactin0.970 0.920 0.810 0.850 1.400 1.020 0.880
KLA/Compactin0.940 0.840 0.620 0.450 0.760 1.040 1.200
B4galt1
KLA  Compactin  Compactin+KLA
 NM_022305 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (B4galt1), mRNA [NM_022305] KLA1.000 1.100 1.030 0.990 1.030 1.140 1.240
Compactin0.970 0.950 0.990 0.980 0.990 1.040 1.050
KLA/Compactin0.900 1.060 0.950 1.060 0.980 1.070 1.210
B4galt2
KLA  Compactin  Compactin+KLA
 NM_017377 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 (B4galt2), mRNA [NM_017377] KLA0.880 0.920 1.020 1.070 1.010 1.210 0.930
Compactin0.990 1.110 0.970 1.010 1.000 0.940 0.960
KLA/Compactin0.930 1.020 1.000 0.990 1.030 1.040 1.020
B4galt2
KLA  Compactin  Compactin+KLA
 NM_017377 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 (B4galt2), mRNA [NM_017377] KLA1.010 1.050 0.990 1.030 0.960 1.000 0.950
Compactin0.910 1.020 0.960 0.960 0.980 1.030 0.900
KLA/Compactin0.930 1.170 1.010 0.970 0.970 1.010 0.970
G6pc
KLA  Compactin  Compactin+KLA
 NM_008061 glucose-6-phosphatase, catalytic (G6pc), mRNA [NM_008061] KLA1.080 0.980 0.880 1.060 1.040 1.050 0.960
Compactin1.020 0.970 1.000 0.950 1.030 1.090 0.960
KLA/Compactin0.860 1.000 1.090 1.010 1.050 1.020 1.090
G6pc2
KLA  Compactin  Compactin+KLA
 NM_021331 glucose-6-phosphatase, catalytic, 2 (G6pc2), mRNA [NM_021331] KLA1.080 1.030 1.010 1.080 1.010 1.020 0.940
Compactin0.970 1.030 1.050 0.950 1.050 1.060 0.980
KLA/Compactin1.000 1.050 1.080 1.010 1.030 0.980 0.920
G6pc3
KLA  Compactin  Compactin+KLA
 NM_175935 glucose 6 phosphatase, catalytic, 3 (G6pc3), mRNA [NM_175935] KLA1.000 0.970 1.040 1.000 0.840 0.830 1.420
Compactin1.010 1.040 1.180 1.060 0.970 1.020 1.030
KLA/Compactin1.070 0.940 1.260 1.010 0.980 1.060 1.100
Gaa
KLA  Compactin  Compactin+KLA
 NM_008064 glucosidase, alpha, acid (Gaa), mRNA [NM_008064] KLA1.130 1.070 1.210 1.000 1.090 1.330 1.470
Compactin1.210 1.210 1.160 1.110 0.770 0.970 0.890
KLA/Compactin1.180 1.120 1.110 1.090 0.980 1.120 1.400
Gale
KLA  Compactin  Compactin+KLA
 NM_178389 galactose-4-epimerase, UDP (Gale), mRNA [NM_178389] KLA0.880 0.840 0.770 0.740 0.810 1.110 1.780
Compactin0.880 0.950 0.990 0.830 1.180 1.500 1.910
KLA/Compactin0.970 0.910 0.760 0.750 0.920 1.350 2.180
Galk1
KLA  Compactin  Compactin+KLA
 NM_016905 galactokinase 1 (Galk1), mRNA [NM_016905] KLA1.080 1.030 1.010 1.060 0.960 0.950 0.810
Compactin0.980 1.180 1.100 1.080 0.920 1.140 1.080
KLA/Compactin0.990 1.170 1.070 1.060 0.840 0.860 0.830
Galk2
KLA  Compactin  Compactin+KLA
 NM_175154 galactokinase 2 (Galk2), mRNA [NM_175154] KLA0.910 0.990 0.860 0.770 0.790 0.870 0.740
Compactin0.790 0.890 0.910 0.810 0.810 0.910 0.780
KLA/Compactin0.810 0.880 0.870 0.890 0.690 0.810 0.780
Galt
KLA  Compactin  Compactin+KLA
 NM_016658 galactose-1-phosphate uridyl transferase (Galt), mRNA [NM_016658] KLA1.060 0.990 1.040 0.840 0.880 1.140 1.500
Compactin1.020 1.110 1.150 1.100 1.120 1.020 1.060
KLA/Compactin0.960 0.900 1.030 0.940 0.900 1.190 1.390
Ganc
KLA  Compactin  Compactin+KLA
 NM_172672 glucosidase, alpha; neutral C (Ganc), mRNA [NM_172672] KLA0.940 0.940 0.870 0.990 0.790 0.770 0.730
Compactin1.000 0.960 0.900 1.030 1.030 0.990 1.060
KLA/Compactin1.000 0.970 0.840 0.880 0.930 0.900 0.790
Ganc
KLA  Compactin  Compactin+KLA
 NM_172672 glucosidase, alpha; neutral C (Ganc), mRNA [NM_172672] KLA0.950 0.970 0.950 1.010 1.030 1.010 1.060
Compactin1.020 1.030 1.010 0.980 1.050 0.990 1.080
KLA/Compactin0.960 0.950 0.910 0.980 0.960 1.010 1.080
Ganc
KLA  Compactin  Compactin+KLA
 NM_172672 glucosidase, alpha; neutral C (Ganc), mRNA [NM_172672] KLA0.960 0.930 0.880 0.960 0.970 0.950 0.860
Compactin0.970 1.000 0.980 0.930 1.080 1.040 0.960
KLA/Compactin0.990 1.010 1.000 0.930 0.980 0.990 0.920
Gck
KLA  Compactin  Compactin+KLA
 NM_010292 glucokinase (Gck), mRNA [NM_010292] KLA1.000 0.990 1.040 0.930 1.030 1.070 1.020
Compactin0.950 1.000 1.010 0.990 0.950 1.030 1.090
KLA/Compactin0.980 0.960 1.040 0.990 1.040 0.760 0.860
Gck
KLA  Compactin  Compactin+KLA
 NM_010292 glucokinase (Gck), mRNA [NM_010292] KLA1.050 0.930 1.000 1.000 0.970 1.110 1.040
Compactin0.970 0.950 0.980 1.010 1.010 0.980 0.960
KLA/Compactin0.940 1.000 0.990 1.000 0.950 0.960 1.010
Gla
KLA  Compactin  Compactin+KLA
 NM_013463 galactosidase, alpha (Gla), mRNA [NM_013463] KLA1.050 1.070 1.090 0.940 0.920 1.260 1.400
Compactin1.080 1.050 0.980 1.050 0.780 0.650 0.640
KLA/Compactin1.080 1.000 1.030 0.850 0.720 1.000 1.090
Gla
KLA  Compactin  Compactin+KLA
 U34071 alpha-galactosidase A mRNA, complete cds. [U34071] KLA1.040 1.040 0.940 0.880 1.050 1.020 1.080
Compactin0.960 0.940 1.000 0.930 0.810 0.750 0.820
KLA/Compactin1.060 0.970 0.890 0.800 0.950 1.010 0.940
Glb1
KLA  Compactin  Compactin+KLA
 NM_009752 galactosidase, beta 1 (Glb1), mRNA [NM_009752] KLA0.930 0.960 1.060 0.950 0.970 1.000 1.320
Compactin1.010 0.960 1.020 1.050 0.970 0.990 1.030
KLA/Compactin1.130 0.950 1.020 0.990 0.900 0.950 1.210
Glb1
KLA  Compactin  Compactin+KLA
 NM_009752 galactosidase, beta 1 (Glb1), mRNA [NM_009752] KLA1.130 1.140 1.090 1.050 0.940 1.080 1.350
Compactin1.220 1.150 1.170 1.250 0.990 1.110 1.160
KLA/Compactin1.290 1.170 1.160 0.940 0.940 1.050 1.180
Glb1
KLA  Compactin  Compactin+KLA
 NM_009752 galactosidase, beta 1 (Glb1), mRNA [NM_009752] KLA1.300 1.220 1.300 1.220 0.950 1.030 1.360
Compactin1.330 1.190 1.310 1.170 1.280 1.160 1.020
KLA/Compactin1.330 1.050 1.190 1.240 0.980 1.040 1.150
Hk1
KLA  Compactin  Compactin+KLA
 J05277 gb|Mouse hexokinase mRNA, complete cds [J05277] KLA0.850 0.880 0.770 0.870 1.990 1.830 2.040
Compactin0.920 0.970 0.860 0.820 1.130 1.400 1.340
KLA/Compactin1.000 0.900 0.890 0.810 1.600 2.030 2.620
Hk1
KLA  Compactin  Compactin+KLA
 NM_010438 hexokinase 1 (Hk1), nuclear gene encoding mitochondrial protein, mRNA [NM_010438] KLA0.860 0.920 0.830 0.960 1.680 1.580 2.270
Compactin0.960 0.910 0.870 0.810 1.150 1.320 1.310
KLA/Compactin0.930 0.880 0.830 0.880 1.560 2.000 3.120
Hk1
KLA  Compactin  Compactin+KLA
 NM_010438 hexokinase 1 (Hk1), nuclear gene encoding mitochondrial protein, mRNA [NM_010438] KLA0.980 1.040 0.990 1.050 1.070 1.040 1.060
Compactin1.100 0.980 1.060 1.060 1.050 1.080 1.050
KLA/Compactin0.980 1.030 1.000 0.980 1.040 1.210 1.110
Hk1
KLA  Compactin  Compactin+KLA
 NM_010438 hexokinase 1 (Hk1), nuclear gene encoding mitochondrial protein, mRNA [NM_010438] KLA1.000 0.950 0.930 0.950 1.470 1.620 1.990
Compactin1.020 0.920 0.940 1.040 1.040 1.240 1.160
KLA/Compactin1.000 0.970 0.970 0.980 1.650 1.880 2.220
Hk1
KLA  Compactin  Compactin+KLA
 NM_010438 hexokinase 1 (Hk1), nuclear gene encoding mitochondrial protein, mRNA [NM_010438] KLA1.010 1.010 1.030 1.030 1.610 1.610 2.370
Compactin1.000 0.990 1.030 1.090 1.120 1.320 1.390
KLA/Compactin1.030 1.070 0.980 1.040 1.570 2.210 2.730
Hk2
KLA  Compactin  Compactin+KLA
 NM_013820 hexokinase 2 (Hk2), mRNA [NM_013820] KLA1.080 1.150 1.110 1.620 1.550 1.530 1.480
Compactin0.880 0.980 0.930 0.980 1.020 1.150 1.050
KLA/Compactin1.050 1.250 1.000 1.710 1.500 1.530 1.430
Hk3
KLA  Compactin  Compactin+KLA
 NM_001033245 hexokinase 3 (Hk3), nuclear gene encoding mitochondrial protein, mRNA [NM_001033245] KLA1.110 1.060 0.940 1.510 2.390 3.090 2.140
Compactin1.070 1.160 1.090 1.160 0.880 0.870 1.230
KLA/Compactin1.170 1.060 0.890 1.210 2.010 2.560 1.710
Hkdc1
KLA  Compactin  Compactin+KLA
 NM_145419 hexokinase domain containing 1 (Hkdc1), mRNA [NM_145419] KLA0.970 1.020 1.010 1.000 1.020 0.960 1.080
Compactin1.030 0.960 0.890 1.060 1.010 0.960 0.950
KLA/Compactin1.090 1.000 0.940 0.960 0.970 1.040 0.980
Lalba
KLA  Compactin  Compactin+KLA
 NM_010679 lactalbumin, alpha (Lalba), mRNA [NM_010679] KLA1.210 1.080 1.090 1.080 1.070 1.020 1.090
Compactin1.070 1.010 1.120 1.050 1.120 1.100 1.000
KLA/Compactin1.030 1.110 1.190 1.180 1.090 1.090 1.140
Lct
KLA  Compactin  Compactin+KLA
 124487296 lactase KLA1.030 1.070 1.100 1.050 0.960 0.950 1.180
Compactin1.080 1.010 1.170 1.120 1.150 1.130 1.220
KLA/Compactin1.070 1.040 1.120 1.130 0.880 0.990 1.070
Lct
KLA  Compactin  Compactin+KLA
 NM_001081078 lactase (Lct), mRNA [NM_001081078] KLA0.990 1.000 0.940 1.020 0.990 0.970 1.010
Compactin1.070 1.090 0.970 0.980 1.080 1.000 1.030
KLA/Compactin0.970 0.940 1.000 0.980 1.000 0.990 0.990
Mgam
KLA  Compactin  Compactin+KLA
 149255058 maltase-glucoamylase KLA0.970 0.950 1.010 1.030 0.990 1.020 1.010
Compactin1.060 0.980 0.990 1.000 1.000 1.070 0.990
KLA/Compactin0.990 1.100 1.010 0.960 0.990 1.020 0.980
Mgam
KLA  Compactin  Compactin+KLA
 AK033548 adult male colon cDNA, RIKEN full-length enriched library, clone:9030616M21 product:hypothetical protein, full insert sequence. [AK033548] KLA0.920 0.970 0.950 0.940 0.930 0.810 0.850
Compactin1.000 0.980 1.010 1.060 1.030 0.960 1.040
KLA/Compactin0.990 0.960 0.940 1.000 0.970 0.870 0.780
Mgam
KLA  Compactin  Compactin+KLA
 XM_001481277 gb|PREDICTED: Mus musculus maltase-glucoamylase (Mgam), mRNA [XM_001481277] KLA1.020 0.990 1.010 1.000 1.000 1.000 0.960
Compactin1.120 1.010 0.930 1.150 1.040 0.960 0.950
KLA/Compactin1.030 0.940 1.000 0.910 1.000 0.930 0.950
Pfkl
KLA  Compactin  Compactin+KLA
 NM_008826 phosphofructokinase, liver, B-type (Pfkl), mRNA [NM_008826] KLA0.830 1.080 0.730 0.910 0.960 0.670 0.660
Compactin0.890 0.960 0.920 0.790 1.180 1.300 0.970
KLA/Compactin0.870 1.220 0.910 1.040 0.800 0.680 0.800
Pfkm
KLA  Compactin  Compactin+KLA
 NM_021514 phosphofructokinase, muscle (Pfkm), mRNA [NM_021514] KLA0.940 0.740 0.850 0.790 0.560 0.440 0.440
Compactin0.980 0.990 0.970 0.880 1.070 1.010 0.800
KLA/Compactin0.900 0.910 0.810 0.790 0.500 0.510 0.360
Pfkp
KLA  Compactin  Compactin+KLA
 BC050264 gb|Mus musculus, clone IMAGE:4503748, mRNA [BC050264] KLA1.130 1.530 1.950 1.130 1.270 1.120 0.440
Compactin0.880 0.990 0.920 0.690 1.390 1.250 1.490
KLA/Compactin1.240 1.470 2.070 1.360 0.910 0.740 0.580
Pfkp
KLA  Compactin  Compactin+KLA
 NM_019703 phosphofructokinase, platelet (Pfkp), mRNA [NM_019703] KLA0.960 0.990 1.280 1.510 1.710 1.280 1.370
Compactin0.910 0.940 1.020 0.820 1.130 1.180 1.370
KLA/Compactin0.920 1.130 1.160 1.400 1.750 1.500 1.740
Pfkp
KLA  Compactin  Compactin+KLA
 NM_019703 phosphofructokinase, platelet (Pfkp), mRNA [NM_019703] KLA1.040 1.090 1.150 1.120 0.980 0.780 0.740
Compactin1.050 1.120 1.010 1.130 1.030 1.000 1.100
KLA/Compactin1.100 1.100 1.120 1.160 1.040 0.790 0.690
Pgm1
KLA  Compactin  Compactin+KLA
 NM_025700 phosphoglucomutase 1 (Pgm1), mRNA [NM_025700] KLA0.960 1.160 1.330 1.370 1.200 1.250 1.940
Compactin0.920 0.990 1.020 0.870 0.950 1.080 1.130
KLA/Compactin0.950 1.210 1.480 1.380 1.420 1.670 2.270
Pgm2
KLA  Compactin  Compactin+KLA
 NM_028132 phosphoglucomutase 2 (Pgm2), mRNA [NM_028132] KLA1.030 1.070 0.940 1.090 1.170 1.320 1.680
Compactin1.180 1.190 1.030 1.140 1.080 1.010 0.980
KLA/Compactin1.260 1.150 0.980 1.050 1.300 1.580 1.820
Ugp2
KLA  Compactin  Compactin+KLA
 NM_139297 UDP-glucose pyrophosphorylase 2 (Ugp2), mRNA [NM_139297] KLA0.790 0.860 0.900 0.960 0.870 1.290 2.530
Compactin0.850 0.920 0.840 1.000 0.960 1.040 1.300
KLA/Compactin0.870 0.930 0.950 0.860 1.160 1.640 2.410
Ugp2
KLA  Compactin  Compactin+KLA
 NM_139297 UDP-glucose pyrophosphorylase 2 (Ugp2), mRNA [NM_139297] KLA1.060 1.060 1.070 1.020 0.970 1.010 1.320
Compactin1.170 1.030 1.100 1.130 1.020 0.960 1.260
KLA/Compactin1.090 0.960 1.120 1.080 1.040 0.990 1.310