LMPD Database

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LMP012736

Record overview

LMPD IDLMP012736
Gene ID78959
SpeciesMacaca mulata (Rhesus monkey)
Gene Namealdo-keto reductase family 1, member A1 (aldehyde reductase)
Gene SymbolAkr1a1
SynonymsAkr1a4;
Alternate namesalcohol dehydrogenase [NADP(+)]; aldehyde reductase; 3-DG-reducing enzyme; alcohol dehydrogenase; aldo-keto reductase family 1 member A1;
Chromosome5
Map Location5q36
EC Number1.1.1.2
Summaryenzyme that catalyzes the NADPH-dependent reduction of 3-deoxyglucosone; important for detoxifying 3-deoxyglucosone when it is formed through the Maillard reaction in vivo [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Akr1a1

Proteins

alcohol dehydrogenase [NADP(+)]
Refseq ID:NP_112262
Protein GI:13591894
UniProt ID:P51635
mRNA ID:NM_031000
Length:325
RefSeq Status:
MTASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPREELFVTSKLWNTKHHPEDVEPAVRKTLA
DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVKYDSTHYKETWKALEALVAKGLVKALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHC
QARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSITPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIV
PMITVDGKRVPRDAGHPLYPFNDPY