LMPD Database

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LMP012394

Gene Information

Entrez Gene ID24242
Gene Namecalmodulin 1
Gene SymbolCalm1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0034704 IEA:EnsemblCcalcium channel complex
GO:0005813 IEA:EnsemblCcentrosome
GO:0005737 IDA:RGDCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IEA:EnsemblCextracellular vesicular exosome
GO:0030426 IDA:RGDCgrowth cone
GO:0043005 IDA:RGDCneuron projection
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:RGDCnucleus
GO:0005886 IDA:RGDCplasma membrane
GO:0030017 IEA:EnsemblCsarcomere
GO:0005876 IEA:EnsemblCspindle microtubule
GO:0000922 IEA:EnsemblCspindle pole
GO:0008179 IDA:RGDFadenylate cyclase binding
GO:0005246 NAS:RGDFcalcium channel regulator activity
GO:0005509 IDA:RGDFcalcium ion binding
GO:0048306 IPI:RGDFcalcium-dependent protein binding
GO:0030234 IMP:RGDFenzyme regulator activity
GO:0044325 IDA:RGDFion channel binding
GO:0050998 IDA:RGDFnitric-oxide synthase binding
GO:0030235 IDA:RGDFnitric-oxide synthase regulator activity
GO:0043548 IPI:RGDFphosphatidylinositol 3-kinase binding
GO:0047485 IMP:RGDFprotein N-terminus binding
GO:0019904 IPI:RGDFprotein domain specific binding
GO:0072542 IEA:EnsemblFprotein phosphatase activator activity
GO:0031800 IPI:RGDFtype 3 metabotropic glutamate receptor binding
GO:0007190 IDA:RGDPactivation of adenylate cyclase activity
GO:0019722 IMP:RGDPcalcium-mediated signaling
GO:0005513 IEA:EnsemblPdetection of calcium ion
GO:0051343 IEA:EnsemblPpositive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051000 IDA:RGDPpositive regulation of nitric-oxide synthase activity
GO:0032516 IEA:EnsemblPpositive regulation of phosphoprotein phosphatase activity
GO:0035307 IEA:EnsemblPpositive regulation of protein dephosphorylation
GO:0060316 IEA:EnsemblPpositive regulation of ryanodine-sensitive calcium-release channel activity
GO:0055117 IEA:EnsemblPregulation of cardiac muscle contraction
GO:0032465 IEA:EnsemblPregulation of cytokinesis
GO:0002027 IEA:EnsemblPregulation of heart rate
GO:1901841 IMP:RGDPregulation of high voltage-gated calcium channel activity
GO:0010880 IEA:EnsemblPregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0060314 IDA:RGDPregulation of ryanodine-sensitive calcium-release channel activity
GO:1901339 IC:RGDPregulation of store-operated calcium channel activity
GO:0001975 IEP:RGDPresponse to amphetamine
GO:0051412 IEP:RGDPresponse to corticosterone
GO:0021762 IEA:EnsemblPsubstantia nigra development
KEGG Pathway Links
KEGG Pathway IDDescription
ko04261Adrenergic signaling in cardiomyocytes
rno04261Adrenergic signaling in cardiomyocytes
ko05034Alcoholism
rno05034Alcoholism
ko05010Alzheimer's disease
rno05010Alzheimer's disease
ko05031Amphetamine addiction
rno05031Amphetamine addiction
ko04020Calcium signaling pathway
rno04020Calcium signaling pathway
ko04713Circadian entrainment
rno04713Circadian entrainment
ko04728Dopaminergic synapse
rno04728Dopaminergic synapse
ko04915Estrogen signaling pathway
rno04915Estrogen signaling pathway
ko04971Gastric acid secretion
rno04971Gastric acid secretion
ko05214Glioma
rno05214Glioma
ko04912GnRH signaling pathway
rno04912GnRH signaling pathway
ko04750Inflammatory mediator regulation of TRP channels
rno04750Inflammatory mediator regulation of TRP channels
ko04910Insulin signaling pathway
rno04910Insulin signaling pathway
ko04720Long-term potentiation
rno04720Long-term potentiation
ko04916Melanogenesis
rno04916Melanogenesis
ko04722Neurotrophin signaling pathway
rno04722Neurotrophin signaling pathway
ko04740Olfactory transduction
rno04740Olfactory transduction
ko04114Oocyte meiosis
rno04114Oocyte meiosis
ko04921Oxytocin signaling pathway
rno04921Oxytocin signaling pathway
ko05133Pertussis
rno05133Pertussis
ko04070Phosphatidylinositol signaling system
rno04070Phosphatidylinositol signaling system
ko04744Phototransduction
rno04744Phototransduction
ko04015Rap1 signaling pathway
rno04015Rap1 signaling pathway
rno04014Ras signaling pathway
ko04970Salivary secretion
rno04970Salivary secretion
ko05152Tuberculosis
rno05152Tuberculosis
ko04270Vascular smooth muscle contraction
rno04270Vascular smooth muscle contraction
ko04024cAMP signaling pathway
rno04024cAMP signaling pathway
ko04022cGMP-PKG signaling pathway
rno04022cGMP-PKG signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
5954317Activation of Ca-permeable Kainate Receptor
5953602Activation of CaMK IV
5954319Activation of Kainate Receptors upon glutamate binding
5953605Activation of NMDA receptor upon glutamate binding and postsynaptic events
5953415Adaptive Immune System
5953413Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
5954296CREB phosphorylation through the activation of CaMKII
5953603CREB phosphorylation through the activation of CaMKK
5954295CREB phosphorylation through the activation of Ras
5953387Ca-dependent events
5953801Ca2+ pathway
5953386CaM pathway
5953597CaMK IV-mediated phosphorylation of CREB
5953598Calmodulin induced events
5953615Cam-PDE 1 activation
5953392DAG and IP3 signaling
5953408DAP12 interactions
5953407DAP12 signaling
5953612DARPP-32 events
5953253Disease
5953382Diseases associated with visual transduction
5953396Downstream signal transduction
5953399Downstream signaling of activated FGFR
5953402EGFR interacts with phospholipase C-gamma
5953416FCERI mediated Ca+2 mobilization
5953417Fc epsilon receptor (FCERI) signaling
5953389G-protein mediated events
5953248Glucose metabolism
5953266Glycogen breakdown (glycogenolysis)
5953252Glycogen storage diseases
5953645Hemostasis
5953410Immune System
5953378Inactivation, recovery and regulation of the phototransduction cascade
5953409Innate Immune System
5954515Inositol phosphate metabolism
5954318Ionotropic activity of Kainate Receptors
5953916Membrane Trafficking
5953250Metabolism
5953249Metabolism of carbohydrates
5954034Metabolism of nitric oxide
5953600Mitochondrial biogenesis
5953412Muscle contraction
5953251Myoclonic epilepsy of Lafora
5953394NGF signalling via TRKA from the plasma membrane
5953277Neuronal System
5953606Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
5953390Opioid Signalling
5953601Organelle biogenesis and maintenance
5953388PLC beta mediated events
5953393PLC-gamma1 signalling
5953405PLCG1 events in ERBB2 signaling
5953398Phospholipase C-mediated cascade
5953644Platelet activation, signaling and aggregation
5954102Platelet degranulation
5953604Post NMDA receptor activation events
5954297Ras activation uopn Ca2+ infux through NMDA receptor
5953646Response to elevated platelet cytosolic Ca2+
5953381Signal Transduction
5953403Signaling by EGFR
5953404Signaling by EGFR in Cancer
5953406Signaling by ERBB2
5953400Signaling by FGFR
5953401Signaling by FGFR in disease
5953391Signaling by GPCR
5953397Signaling by PDGF
5953420Signaling by VEGF
5953803Signaling by Wnt
5953414Signaling by the B Cell Receptor (BCR)
5953395Signalling by NGF
5953411Smooth Muscle Contraction
5954514Synthesis of IP3 and IP4 in the cytosol
5954461Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
5953379The phototransduction cascade
5953599Transcriptional activation of mitochondrial biogenesis
5954455Translocation of GLUT4 to the plasma membrane
5953276Transmission across Chemical Synapses
5953419VEGFA-VEGFR2 Pathway
5953418VEGFR2 mediated cell proliferation
5953999VEGFR2 mediated vascular permeability
5953380Visual phototransduction
5953802beta-catenin independent WNT signaling
5954032eNOS activation
5954033eNOS activation and regulation